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NIH has no active Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) Notices of Funding Opportunity (NOFOs); therefore, there is no April 5, 2026 receipt date (see NOT-OD-26-006). Any future NOFOs will be forecasted at Grants.gov prior to opening for applications.
Learn if your company is eligible for NIH SBIR or STTR funding, how to apply, and what to expect during each step of the application process. Multiple registrations are required to prepare your application and apply for funding.
The NIH is actively turning discovery into health by helping small businesses develop innovative technologies that improve health and save lives. See how.
SiVEC Biotechnologies aims to revolutionize the delivery of nucleic acids and other biologically active cargo to enable the development of safer and more effective therapies. SiVEC is a biopharma partnering company with a mission to provide a novel delivery platform that will support the translation of innovative nucleic acid and gene therapies from the R&D phase to the clinic and finally into the market. The company is focused on developing a drug delivery platform that is characterized as non-pathogenic bacteria that constitutively generate therapeutic nucleic acids for targeted intracellular delivery to mucosal epithelial cells. The bacterial delivery system is currently being used as a vehicle for delivery of an siRNA-based influenza antiviral in preclinical development.