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[Omnibus Solicitations] [Specific Opportunities]

SBIR and STTR grant funding opportunities offer small business entrepreneurs a chance to obtain non-dilutive funding for early-stage research and development. Applications are accepted three times a year. Read on to explore your options.

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Omnibus Solicitations (Parent Announcements)

Researcher-initiated ideas are proposed via the SBIR and STTR Omnibus grant solicitations. These FOAs do not specify a topic, though they link to identified topics of interest for each participating awarding component. Most small business applications to NIH are submitted to the Omnibus solicitations.

Read the Program Descriptions and Research Topics to understand the awarding components, their topics of interest, and staff contacts. For topics that require additional funding to reach the marketplace, please refer to our list of SBA approved waiver eligible topics.

Standard Application Due Dates: September 5, January 5, and April 5. Due dates that fall on weekends or Federal holidays move to the next business day.
 

Title Notice/FOA Number Organization Release Date Due Date(s) Expiration Date Clinical Trials
PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-22-177 OD 06/02/2022 Standard dates apply ...(see announcement for full details) 04/06/2023 Required
PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-22-178 OD 06/02/2022 Standard dates apply...(see announcement for full details) 04/06/2023 Not Allowed
PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PA-22-179 OD 06/02/2022 Standard dates apply...(see announcement for full details) 04/06/2023 Required
PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-22-176 OD 06/02/2022 Standard dates apply ...(see announcement for full details) 04/06/2023 Not Allowed

Specific Funding Opportunities

Some SBIR/STTR grant solicitations are focused on specific research areas. Some specific FOAs, identified as RFAs (Requests for Applications) or PASs (Program Announcements with Set-aside funds), have funding set-aside in the Institute/Center's budget for that targeted program.

Title Notice/FOA Number Organization Release Date Due Date(s) Expiration Date Clinical Trials
Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional) PAS-22-197 NIANINDS 06/21/2022 09/06/2025 Optional
Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional) PAS-22-196 NIANINDS 06/21/2022 09/06/2025 Optional
Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional) PAS-19-317 NIANINDS 07/18/2019 Standard dates apply, by 5:00 PM local time of app...(see announcement for full details) 09/07/2022 Optional
Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional) PAS-19-316 NIANINDS 07/18/2019 Standard dates apply, by 5:00 PM local time of app...(see announcement for full details) 09/07/2022 Optional
Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional) PAR-21-057 NINDS 11/19/2020 February 22, 2021, June 22, 2021, February 22, 202...(see announcement for full details) 09/08/2023 Optional
Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required) RFA-TR-22-029 NCATS 07/13/2022 07/13/2023 Required
Blueprint Medtech: Small Business Translator (U44 - Clinical Trial Optional) PAR-21-282 NIDANIMHNEINIDCRNIAOBSSRNCCIHNIBIBNICHDNIAAANINDS 08/20/2021 October 20, 2021; February 18, 2022; June 20, 2022...(see announcement for full details) 06/21/2024 Optional
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional) PAR-21-233 NINDSNIAAANIANCCIHNICHDNIBIBNIMHOBSSRNIDCRNIDANEI 04/23/2021 August 10, 2021, February 9, 2022, August 9, 2022,...(see announcement for full details) 04/06/2024 Optional
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional) PAR-20-111 NINDSNCCIHNIDCRNIAAANICHDNIDANIANEIOBSSRNIMH 03/03/2020 August 11, 2020, February 9, 2021,August 10, 2021,...(see announcement for full details) 05/08/2023 Optional
Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional) PAR-21-059 NINDS 11/19/2020 March 15, 2021, June 22, 2021, February 22, 2022, ...(see announcement for full details) 09/08/2023 Optional
Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 - Clinical Trial Not Allowed) RFA-DE-23-008 NIDCR 08/02/2022 11/10/2022 Not Allowed
Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (R42 Fast-Track - Clinical Trial Not Allowed) RFA-DE-23-007 NIDCR 08/02/2022 11/10/2022 Not Allowed
Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R43/R44 - Clinical Trial Optional) RFA-DA-23-021 NIDA 03/28/2022 Multiple dates, see announcement....(see announcement for full details) 02/15/2025 Optional
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) PA-20-047 NIMHNCATSNCINEINHGRINIDANIDCRNIEHSNIGMS 01/07/2020 Standard dates apply, by 5:00 PM local time of app...(see announcement for full details) 01/06/2023 Not Allowed
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) PA-20-025 NIMHNIEHSNIGMSNCATSNIDCRNIDANEINHGRI 01/07/2020 Standard dates apply, by 5:00 PM local time of app...(see announcement for full details) 01/06/2023 Not Allowed
Enabling SUD Digital Therapeutics Research to Improve Payor Adoption (R44- Clinical Trial Only) RFA-DA-23-018 NIDA 06/29/2022 11/16/2022 Required
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed) RFA-NS-20-009 NINDSNICHDNIBIBNIMHNIDDKNIAAANCCIHORIPNIANIAMSNHLBINIGMSNCINIMHDNCATSNEININRNIDCRNLM 10/04/2019 January 8, 2020, April 7, 2020, September 9, 2020,...(see announcement for full details) 09/09/2022 Not Allowed
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required) RFA-NS-20-008 NINDSNCCIHNCINEINHLBINIANIAAANIAMSNIBIBNICHDNIDDKNIGMSNIMHNIMHDNINR 10/04/2019 January 8, 2020, April 7, 2020, September 9, 2020,...(see announcement for full details) 09/09/2022 Required
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed) RFA-NS-20-011 NINDSNIAAANIANIAMSNCCIHNCINIDDKNIGMSNICHDNIBIBNIMHDNLMNIMHNINRNCATSORIPNHLBINIDCRNEI 10/04/2019 January 8, 2020, April 7, 2020, September 9, 2020,...(see announcement for full details) 09/09/2022 Not Allowed
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required) RFA-NS-20-010 NINDSNCCIHNCINEINHLBINIANIAAANIAMSNIBIBNICHDNIDDKNIGMSNIMHNIMHDNINR 10/04/2019 January 8, 2020, April 7, 2020, September 9, 2020,...(see announcement for full details) 09/09/2022 Required
Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 Clinical Trial Not Allowed) PAR-20-244 NIGMS 06/25/2020 September 4, 2020; September 3, 2021; September 2 ...(see announcement for full details) 09/03/2022 Not Allowed
Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42 Clinical Trial Not Allowed) PAR-20-239 NIGMS 06/25/2020 September 4, 2020; September 3, 2021; September 2,...(see announcement for full details) 09/03/2022 Not Allowed
Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (U43/U44 Clinical Trial Optional) PAR-22-102 NIAAA 01/21/2022 Multiple dates, see announcement....(see announcement for full details) 12/05/2024 Optional
Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (UT1/UT2 Clinical Trial Optional) PAR-22-103 NIAAA 01/21/2022 Multiple dates, see announcement....(see announcement for full details) 12/05/2024 Optional
Late-Stage Translation of Biomedical and Behavioral Research Results in Arthritis and Musculoskeletal and Skin Diseases from Academic/Non-profit Lab to Marketplace (SBIR [R43/R44] Clinical Trial Not Allowed) PAR-21-030 NIAMS 10/08/2020 Standard datesapply The first standard due date f...(see announcement for full details) 09/06/2022 Not Allowed
Multipurpose Prevention Technology: Novel Systemic Options for Young Adults (R41/R42 Clinical Trial Not Allowed) PAR-21-298 NICHDNIMH 08/31/2021 Only accepting applications for the AIDS Applicati...(see announcement for full details) 12/10/2023 Not Allowed
Multipurpose Prevention Technology: Novel Systemic Options for Young Adults (R43/R44 Clinical Trial Not Allowed) PAR-21-297 NICHDNIAIDNIMH 08/31/2021 Only accepting applications for the AIDS Applicati...(see announcement for full details) 12/10/2023 Not Allowed
NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional) PAR-21-224 NINDS 05/05/2021 Standard dates apply *** Note new SBIR/STTR Standa...(see announcement for full details) 04/06/2024 Optional
New Approaches for Incorporating Genetic Diversity into Toxicity Testing (R43/R44 Clinical Trial Not Allowed) RFA-ES-22-006 NIEHS 06/30/2022 11/09/2022 Not Allowed
NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) RFA-HL-23-009 NHLBI 11/16/2021 02/29/2024 Optional
NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) RFA-HL-23-008 NHLBINCATS 11/16/2021 02/29/2024 Optional
NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional) RFA-AG-23-030 NIA 07/06/2022 02/18/2023 Optional
NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R43/R44 Clinical Trial Optional) RFA-AG-23-029 NIA 07/06/2022 02/18/2023 Optional
NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required) PAR-21-082 NIAID 01/14/2021 May 14, 2021; September 13, 2021; January 14, 2022...(see announcement for full details) 01/14/2024 Required
NINDS Exploratory Clinical Trials for Small Business (R41/R42 Clinical Trial Required) PAR-21-267 NINDS 07/16/2021 Standard dates apply The first standard due date f...(see announcement for full details) 04/06/2024 Required
NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required) PAR-21-266 NINDS 07/15/2021 Standard dates apply The first standard due date f...(see announcement for full details) 04/06/2024 Required
NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Clinical Trials and Clinical Research (R44 Clinical Trial Optional) PAR-21-265 NINDS 07/15/2021 Standard dates apply The first standard due date f...(see announcement for full details) 04/06/2024 Optional
NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44 Clinical Trial Not Allowed) PAR-21-114 NINDS 01/25/2021 Standard dates apply The first standard due date f...(see announcement for full details) 01/06/2024 Not Allowed
Notice of Special Interest (NOSI): Next-Generation Approaches to Renal Replacement Therapy Including Vascular Access NOT-DK-19-027 NIDDKNIBIBNCATS 10/09/2019 01/07/2023 Not Allowed
Notice of Special Interest (NOSI) for the NEI Anterior Segment Initiative (ASI): Identification and Development of New Biomarkers and Effective methods to Diagnose Dry Eye Disease. NOT-EY-21-007 NEI 12/21/2020 05/08/2023 Optional
Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches NOT-DE-20-006 NIDCR 06/05/2020 08/08/2023 Not Allowed
Notice of Special Interest (NOSI): Accelerating Progress in Celiac Disease Research NOT-AI-22-004 NIAIDNIAMSNCCIHNCI 11/23/2021 01/08/2025 Optional
Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration NOT-EY-22-002 NEI 01/10/2022 02/10/2025 Optional
Notice of Special Interest (NOSI): HIV Drug Resistance Assays and Actionable Data Dissemination Strategies NOT-AI-21-056 NIAIDNIDA 06/17/2021 05/08/2024 Not Allowed
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health (R43/R44 Small Business Innovation Research (R43/R44 Clinical Trial Optional) NOT-ES-22-010 NIEHSNCATSNEINHLBINIANIAIDNIAMSNICHDNIMHNIMHDNINRNLM 06/03/2022 04/06/2023 Optional
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health Small Business Technology Transfer (R41/R42 Clinical Trial Optional) NOT-ES-22-009 NIEHSNCATSNEINHLBINIANIAIDNICHDNIMHNIMHDNINR 06/03/2022 04/06/2023 Optional
Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease NOT-HG-22-007 NHGRI 12/09/2021 11/05/2024 Not Allowed
Notice of Special Interest (NOSI): Addressing Accessibility Inequities with COVID Home-Based Testing for Individuals with Visual Impairment NOT-EY-22-010 NEI 02/04/2022 03/09/2024 Optional
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-20-013 NIAIDNIBIB 12/17/2019 01/08/2023 Not Allowed
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-21-018 NHGRI 12/04/2020 01/10/2024 Not Allowed
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 NIDCR 09/01/2021 09/05/2025 Not Allowed
Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment NOT-HD-21-053 NICHD 12/28/2021 05/08/2024 Optional
Notice of Special Interest (NOSI): BRAIN Initiative: Translation of Groundbreaking Technologies from Early-stage Development through Early Clinical Study via Blueprint MedTech NOT-NS-22-052 NINDSNIAAANIBIBNCCIHNEINIANICHDOBSSRNIDCDNIDANIMH 01/05/2022 06/21/2024 Optional
Notice of Special Interest (NOSI): Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (SBIR/STTR) NOT-AT-21-001 NCCIH 10/23/2020 01/05/2024 Optional
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA 12/09/2021 09/09/2025 Optional
Notice of Special Interest (NOSI): Genomics Education Interactive Digital Media Resources (SBIR/STTR) NOT-HG-21-038 NHGRI 08/26/2021 12/31/2024 Not Allowed
Notice of Special Interest (NOSI): HEAL Initiative: Clinical Translation of Diagnostic and Therapeutic Devices via Blueprint MedTech NOT-NS-23-002 NINDSNCCIHNCINEINIANIAAANIAMSNICHDNIDANIDCRNIMH 08/03/2022 06/21/2024 Optional
Notice of Special Interest (NOSI): Hearing Healthcare for Adults: Improving Access and Affordability NOT-DC-21-001 NIDCD 02/16/2021 01/08/2024 Optional
Notice of Special Interest (NOSI): Implementation Science to Advance the United States HIV Prevention and Treatment Goals and the Global HIV Prevention and Treatment Targets NOT-MH-20-024 NIMH 03/30/2020 05/08/2023 Optional
Notice of Special Interest (NOSI): Improving Methods to Assess Body Composition in Infants and Young Children NOT-DK-20-036 NIDDKNIBIB 07/23/2020 09/05/2022 Not Allowed
Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health NOT-OD-21-100 OBSSRNIMHDNIDANIMHORWHNIDCDSGMROODPNIANHLBINCININRNCCIHNEINICHD 04/08/2021 06/08/2024 Optional
Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities (R43/R44) NOT-HD-22-009 NICHD 06/07/2022 04/06/2023 Optional
Notice of Special Interest (NOSI): Mental Health Comorbidities in HIV Prevention and Treatment NOT-MH-20-013 NIMH 03/30/2020 05/08/2023 Optional
Notice of Special Interest (NOSI): Methods Development in Natural Products Research (SBIR/STTR) NOT-AT-20-015 NCCIH 07/16/2020 09/06/2023 Not Allowed
Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings NOT-CA-21-062 NCI 07/23/2021 09/07/2024 Optional
Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition NOT-HD-21-027 NICHDNIAAANCINIMHNIAMSOBSSRNIBIBNIDCR 06/22/2021 01/08/2024 Optional
Notice of Special Interest (NOSI): NIDCD is Interested in Supporting Research on the Impact of COVID-19 on Mission Specific Sensory and Communication Disorders NOT-DC-20-008 NIDCD 06/04/2020 09/08/2022 Optional
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services NOT-MH-22-110 NIMHNIDAORWH 02/08/2022 05/08/2025 Optional
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEINIMHD 02/14/2022 01/25/2025 Optional
Notice of Special Interest (NOSI): Research in the Emergency Setting NOT-NS-20-005 NINDSNCINIDANHLBINIDCDNIAAANICHDNIANIGMSNEINIMHDNIMH 09/08/2020 09/08/2022 Optional
Notice of Special Interest (NOSI): Research on Strategies to Enhance Mental Health Interventions and Services within Employment and Job Training Settings NOT-MH-21-230 NIMHNIDA 04/16/2021 09/08/2023 Optional
Notice of Special Interest (NOSI): Research to Support Regulatory Science on Infant Formula NOT-HD-22-016 NICHDODODS 06/13/2022 05/08/2023 Optional
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health NOT-EB-21-001 NIBIBNIAIDORWHNICHDNIMHDNIMHNINDSODNCATSNHLBINHGRI 02/22/2021 04/06/2023 Optional
Notice of Special Interest (NOSI): Strengthening the HIV Care Continuum NOT-MH-20-023 NIMH 03/30/2020 05/08/2023 Optional
Notice of Special Interest (NOSI): Strengthening the HIV Prevention Continuum NOT-MH-20-019 NIMH 03/27/2020 05/08/2023 Optional
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-22-006 NIBIB 03/21/2022 05/08/2024 Optional
Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection NOT-AI-22-043 NIAID 04/29/2022 05/08/2025 Not Allowed
Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace NOT-MH-21-125 NIMHNIANIAAANIBIBNINDSNIDANEINCCIHNICHDNIDCD 03/03/2021 01/06/2024 Not Allowed
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes NOT-CA-21-031 NCINIA 01/27/2021 01/08/2024 Optional
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research NOT-CA-22-037 NCINHLBINIANIDANIMHNINROBSSR 01/27/2022 03/09/2024 Optional
Notice of Special Interest: Advancing Research for Tickborne Diseases (TBDs) NOT-AI-20-005 NIAIDNCCIHNIAMSNIMHNINDS 11/12/2019 01/08/2023 Optional
Notice of Special Interest: Biomarker Discover and Validation in Functional Neurological Disorders NOT-NS-22-010 NINDS 10/01/2021 01/08/2025 Optional
Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients Use of Genomic Information NOT-HG-22-011 NHGRI 01/06/2022 12/31/2025 Optional
Notice of Special Interest: Development of Swallowable Smart Pills or Devices for Precision Nutrition, Microbiome and Digestive Disease Applications NOT-DK-20-001 NIDDK 11/01/2019 01/08/2023 Optional
Notice of Special Interest: Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults NOT-MH-20-035 NIMH 04/01/2020 05/08/2023 Optional
Notice of Special Interest: Kidney Precision Medicine Technology Development and Translation NOT-DK-21-007 NIDDK 12/02/2020 09/06/2023 Optional
Notice of Special Interest: NIDCD Health Disparities and Inequities Research NOT-DC-21-003 NIDCDSGMRO 06/11/2021 05/08/2024 Optional
Notice of Special Interest: NIGMS Priorities for Small Business Development of Sepsis Diagnostics and Therapeutics NOT-GM-20-028 NIGMS 06/02/2020 09/12/2023 Optional
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA 12/22/2021 01/08/2025 Optional
Notice of Special Interest: SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed) NOT-NS-22-017 NINDSNIDCRNEINCINIA 11/12/2021 01/08/2025 Not Allowed
Notice of Special Interest: Small Business Development of Wearable Smart Devices for Continuous Monitoring of Circulating Nutrients, Metabolites and Hormones NOT-DK-20-002 NIDDK 11/06/2019 01/08/2023 Optional
Notice of Special Interest: Stigma or Other Social Determinants of Health (SDOH) in HIV Prevention and Treatment NOT-MH-20-020 NIMH 03/30/2020 05/08/2023 Optional
Novel Drug (DDT) and Medical Device Development Tools (MDDT) to Help Expedite Creation and Regulatory Approvals of New Therapies for Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional) RFA-DA-23-019 NIDA 06/10/2022 November 14, 2022...(see announcement for full details) 11/15/2022 Optional
Novel Drug (DDT) and Medical Device Development Tools (MDDT) to Help Expedite Creation and Regulatory Approvals of New Therapies for Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional) RFA-DA-23-020 NIDA 06/10/2022 November 14, 2022...(see announcement for full details) 11/15/2022 Optional
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed) PAR-21-226 ORIP 04/30/2021 Standard dates apply The first standard due date f...(see announcement for full details) 09/06/2024 Not Allowed
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed) PAR-21-225 ORIP 04/30/2021 Standard dates apply The first standard due date f...(see announcement for full details) 09/06/2024 Not Allowed
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed) PAR-20-128 NIHNIAMSNIDCRNIBIBNIMHNIDCDNIGMSNIDDKNIEHSNCATSNLMNCCIHNEINHGRINIAAANHLBINCINIA 07/10/2020 All applications are due by 5:00 PM local time of ...(see announcement for full details) 04/06/2023 Not Allowed
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Required) PAR-20-130 NIHNIDCDNINDSNIMHNIANEINHLBINICHDNIAAA 07/10/2020 Standard dates apply All applications are due by ...(see announcement for full details) 04/06/2023 Required
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed) PAR-20-129 NIHNIAMSNIDCDNIDCRNEINIAIDNIGMSNIDDKNIMHNINDSNIAAANHLBINICHDNIA 07/10/2020 Standard dates apply All applications are due by ...(see announcement for full details) 04/06/2023 Not Allowed
Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed) RFA-CA-22-017 NCINIBIBNIDA 03/21/2022 Not Applicable...(see announcement for full details) 08/23/2022 Not Allowed
Support for Small Business Innovation Research (SBIR) to Develop New Methods and Technologies for Assessment of Risk and for Early Diagnosis and Prognosis of Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed) RFA-DK-21-021 NIDDKNIAID 06/25/2021 February 17, 2022 and October 7, 2022 ...(see announcement for full details) 10/08/2022 Not Allowed
Support for Small Business Innovation Research (SBIR) to Develop New Technologies for Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R43/R44 Clinical Trial Not Allowed) RFA-DK-21-011 NIDDK 05/06/2021 March 9, 2022 and October 7, 2022 ...(see announcement for full details) 10/08/2022 Not Allowed
Support for Small Business Innovation Research (SBIR) to Development and Testing of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed) RFA-DK-21-012 NIDDK 05/19/2021 March 9, 2022 and October 7, 2022 ...(see announcement for full details) 10/08/2022 Not Allowed
Technology Development for Single-Molecule Protein Sequencing (R43/R44 Clinical Trial not allowed) PAR-21-247 NHGRINIAIDNCI 07/12/2021 October 1, 2021; June 15, 2022; June 15, 2023 All...(see announcement for full details) 06/16/2023 Not Allowed
Therapeutic Development of Psychoplastogenic Compounds for Substance Use Disorders (R43/R44 - Clinical Trials Not Allowed) RFA-DA-23-017 NIDA 06/24/2022 11/19/2022 Not Allowed
Transformative Nucleic Acid Sequencing Technology Innovation and Early Development (R43/R44) RFA-HG-21-008 NHGRI 03/30/2021 June 25, 2021; March 1, 2022; February 1, 2023 Al...(see announcement for full details) 02/02/2023 Not Allowed
Translational Neural Devices (U44 Clinical Trial Optional) RFA-NS-21-022 NINDS 04/28/2021 July 1, 2021; October 20, 2021; February 18, 2022;...(see announcement for full details) 02/21/2024 Optional