SEED - Helping Innovators turn discovery into health

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NIH is not accepting Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) applications because the legislative authority for the programs expired on October 1, 2025. Active awardees should direct any questions to their Program Officer. See NOT-OD-26-006.

Small Businesses: Review important information about NIH’s foreign disclosure requirement (last updated 05/20/2025)

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Start Your Funding Journey

Review the differences between SBIR and STTR, see current funding opportunities, and find guidance on how to apply.

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Grow Your Business

Move your cutting-edge technology one step closer to market via technical and business assistance programs and hands-on support from industry experts.

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Explore the Nationwide Network

Find out if your institution is part of NIH’s academic network and how public-private partnerships pave the way for promising scientific discoveries.

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SBIR & STTR?

The Road to SBIR or STTR Funding Starts Here

Explore the grant process from idea to award.

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Small Business Research Areas

24 of the NIH’s Institutes fund small business R&D projects through the SBIR and STTR Programs.

Select an Institute to learn more about their mission and how they support small businesses.

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INSTITUTE-SPECIFIC SBIR AND STTR CONTACTS

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INNOVATIONS BACKED BY THE NIH

Success Stories

We support research and development of deep technologies - those that are based on discoveries in fundamental science and engineering. As we review applications, we consider your technology's innovativeness, commercial potential, and possible societal impact.

A Bioabsorbable Clip Enhances Patient Care During Spinal Surgery

Incidental tears in the dura mater, a tough membrane that houses cerebrospinal fluid and protects the brain and spinal cord, are one of the most common complications in lower back surgery.

READ FULL STORY →

Contact The Right Person

Communication is key when applying for a grant or receiving an award. Find that right person to contact at each stage of the process.

WHO TO CONTACT AND WHEN→

National Institutes of Health

Bethesda, MD 20892

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