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Whether you have yet to launch your small business, or are working on your Phase II or IIB application, there are many resources to assist you during both technical and business development endeavors. These resources can include educational opportunities, additional or matching funds, mentorship or training, technical assistance, networking opportunities, and other events and workshops. Many of these are useful across disciplines. 
Below, find resources in the following categories:


Commercialization, Business Development, and Operation

You may find that your local incubator, accelerator, university, or other local networks are the best sources for comprehensive references for commercialization, business development, and operation resources. Beyond these networks, a number of government and non-government groups have prepared resources for all types of small businesses:

National Institutes of Health (NIH)

The NIH offers entrepreneurs and innovators programs and resources to support development of their products. Current offerings can be found on the Support for Awardees page. These include Technical and Business Assistance (TABA), as well as Education programs. The NIDDK is participating in the I-Corps and Concept to Clinic: Commercializing Innovation (C3i) programs.

U.S. Small Business Administration (SBA)

The SBA hosts an extensive library of articles, tools, and other resources for small businesses at any stage of development:

  • - The SBA administers the SBIR & STTR programs and hosts additional resources specific to applicants and awardees at; you may find a useful local event or webinar on their Events page.


The NIDDK and other Institutes and Centers of the NIH are working with industry and trade groups (e.g., AdvaMed and BIO) to provide opportunities to grantees. Eligible grantees will receive emails regarding these opportunities when they become available. In the meantime, find resources from these groups below:

National Science Foundation (NSF)

NSF I-Corps is a program designed to foster entrepreneurship that will lead to the commercialization of technology that has been supported previously by NSF-funded research


Beyond SBA, resources from across the U.S. Federal Government have been centralized at the portal. It may be worth checking to see if any additional resources specific to your needs can be found there.

SCORE, a nonprofit association dedicated to helping small businesses has vast array of resources, including local networks of mentors, business tools and document templates, business counseling, and local and online educational workshops. If you haven’t started a company before, raised money for your company, or taken a life science or medical product to market, having a devoted mentor can be critical. Tap your local network or search through SBA or SCORE to find help.

Do you have banking, accounting, payroll, human resources, or legal needs? Again, tap your local network for advice, and don’t be afraid to ask a candidate service provider for references and their experience working with startups. A number of websites and online services, not affiliated with or endorsed by the federal government, are tailored to startups and small businesses.


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Regulatory, Reimbursement, and Intellectual Property

Many of the technologies developed with the support of NIDDK SBIR & STTR awards will require FDA approval to be used in a clinical study and ultimately to be marketed and sold in the United States. If FDA approval is required for your technology it would behoove you to include some detail of your regulatory strategy in your Commercialization Plan (component of Phase II and IIB applications) and in your progress reports to the NIH. In this section we provide starting points for your consideration of this process as well as some resources pertaining to regulations abroad.

The SF424 (R&R) SBIR/STTR Application Guide offers a list of several resources and references (Section 1.6.1 Other Resources) which may be useful for you in formulating a regulatory strategy. We outline several additional resources below.

U.S. Food and Drug Administration

Keep tabs on regulatory perspective on topics from oversight of next-generation sequencing to new medical devices for treating obesity at the FDA’s official blog, FDA Voices. The FDA assumes a proactive role in the development of a number of technologies relevant to the NIDDK (e.g., the artificial pancreas). Lend your expertise to the conversation. Search for guidance documents and public workshops pertaining to your area of innovation. Several programs offer opportunities for accelerated review, and eligibility or acceptance into these programs may be attractive to investors or partners.

Drugs and Biologics

Information about regulation of drugs and biologics is available from the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER):

Devices and Diagnostics

Information about regulation of devices and diagnostics is available from the FDA's Center for Devices and Radiological Health (CDRH):

Clinical Trials

  • - A registry and results database of publically and privately supported clinical studies; use it to learn about ongoing clinical trials in your area of research and gain insight into study design (e.g., endpoints)
  • EU Clinical Trials Register - Contains information on interventional clinical trials on medicines conducted in the EU or the EEA
  • National Institute of Allergy and Infectious Diseases (NIAID) ClinRegs (BETA) aggregates clinical research regulations from around the globe

Intellectual Property

A strong intellectual property strategy can be critical to gaining access to markets and the success of your small business. One of the benefits of the federal grants is that intellectual property developed with the funds is retained by the company. To help the NIH understand and improve our programs, please comply with requirements to report inventions through iEdison. Educational information regarding intellectual property in the U.S. and globally can be found below.

U.S. Patent and Trademark Office (USPTO)

The USPTO has a broad range of resources which can assist your efforts to develop a strong intellectual property portfolio:

Patent Cooperation Treaty (PCT)

PCT is the International Patent System and also offers several resources:


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Research & Development

NIH Programs

A number of programs at the NIH support translation of therapeutics and other biomedical technologies:

  • Bridging Interventional Development Gaps (BrIDGs) - A program operated by the National Center for Advancing Translational Sciences (NCATS) assists researchers in advancing promising therapeutic agents through late-stage pre-clinical development toward an Investigational New Drug (IND) application; assistance may include scale-up, IND-directed toxicology, and formulation
  • Therapeutics for Rare and Neglected Diseases (TRND) - A program operated by NCATS to speed the development of new drugs for rare and neglected diseases

NIH Portals and Data and Sample Repositories

Many of the NIH’s resources for investigators are also available to for-profit institutions. Confirm data sharing and intellectual property stipulations of each resource align with your commercialization strategy. The following resources could help you continue work in, or direct a platform technology at, a mission area of the NIDDK:


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Regional, State, and Local

Our curated list of state and local resources is currently under development. Contact Daniel Gossett (email) if you need help identifying resources available in your area.

  • The NIH Research Evaluation and Commercialization Hub (REACH) program – Proof-of-concept centers (Hubs) that facilitate and accelerate the translation of biomedical innovations into commercial products; current REACH Hubs are The Long Island Bioscience Hub, The University of Louisville ExCITE Hub, and the University of Minnesota MN-REACH
    • NIH Centers for Accelerated Innovations (NCAI) - At the link above you will also find information about NHLBI-funded NCAI Centers
  • Clinical and Translational Science Award (CTSA) - Institutions funded by these awards have established programs supporting clinical and translational research (collaboration, training, pilot program funding); find a local funded institution

Resources mapped by other sites:


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