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Notice of Special Interest: Encouraging Small Businesses to Partner with Resource-Limited Institutions (NOT-OD-23-179)

NIH SEED launched a new SBIR and STTR initiative to expand the cadre of institutions engaging in the translation of their basic science discoveries to patient and economic benefit: Notice of Special Interest (NOSI): Encouraging Small Businesses to Partner with Resource-Limited Institutions (RLIs) on Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program Applications (NOT-OD-23-179).

NIH provides more than $1.3 billion to support early-stage small businesses through the SBIR and STTR Programs, also known as America’s Seed Fund. These businesses—many of which begin as academic spinouts—often partner with universities and other research institutions to conduct proposed research and development activities, leveraging their deep technical expertise and infrastructure. Through this Notice, small businesses applying for SBIR/STTRs are encouraged to partner with domestic research institutions that received limited research project grant funding in recent years and have a mission or record of educating students from populations underrepresented in biomedical research.

More information is available at NOT-OD-23-179 or by contacting the NIH SEED office at


Date Posted:
January 31, 2024