| ALDATU BIOSCIENCES, INC. |
Commercialization of PANDAA qDx for rapid drug resistance genotyping of protease inhibitor ART failures in resource-limited settings. |
MACLEOD, IAIN JAMES |
NIAID |
Watertown |
MA |
31-July-2025 |
| TING THERAPEUTICS, INC. |
Preclinical evaluation of an otoprotectant TT002 |
HUANG, YUNLONG |
NIDCD |
OMAHA |
NE |
31-July-2025 |
| L2 DIAGNOSTICS, LLC |
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1 |
FIKRIG, EROL |
NIAID |
NEW HAVEN |
CT |
31-July-2025 |
| EXPERIAD, LLC |
Goalspace: A Platform for Parent-Assisted Behavioral Interventions |
JAKOBOVITS, REX M |
NIMH |
HONOLULU |
HI |
31-July-2025 |
| CAPSULOMICS, LLC |
Validation and Early Commercialization of the ENVISAGE Assay, a Prognostic Test for Barrett's Esophagus |
LAUN, SARAH |
NIDDK |
Baltimore |
MD |
31-July-2025 |
| ACURASTEM, INC. |
Development of an UNC13A antisense oligonucleotide treatment for ALS and FTD |
CHANG, WEN-HSUAN |
NINDS |
Monrovia |
CA |
31-July-2025 |
| KILELE HEALTH INC. |
Initial Animal Validation of a Multimodal Molecular Monitor for Heart Failure Treatment |
KARAJIC, ALEKSANDAR |
NHLBI |
OAKWOOD |
OH |
31-July-2025 |
| POP BIOTECHNOLOGIES, INC |
Mosaic Display of Multivalent Tau and A-Beta peptides on Immunogenic SNAP Liposomes |
HUANG, WEI-CHIAO |
NIA |
BUFFALO |
NY |
31-July-2025 |
| TENVOS INC. |
Software as a Medical Device for detecting opioid use through voice. |
SEIILOVA-OLSON, RIMA |
NIDA |
West Sacramento |
CA |
31-July-2025 |
| THERANOVA, LLC |
SoleStim Neuromodulation System, a home-use device for the treatment of dysmenorrhea |
BURNETT, DANIEL ROGERS |
NICHD |
SAN FRANCISCO |
CA |
31-July-2025 |
| PURE GREEN PHARMACEUTICALS, INC. |
Cannabidiol/Palmitoylethanolamide sublingual tablets for the treatment of Painful Diabetic Peripheral Neuropathy |
KIMLESS, DEBRA |
NIDDK |
WEST BLOOMFIELD |
MI |
31-July-2025 |
| QUA, INC. |
Development and Evaluation of the PPAL Bedside Commode for Safe Independent Toileting Transfers |
GRAHAM, MARGARET ELLEN |
NINR |
NEW ROCHELLE |
NY |
31-July-2025 |
| AKONNI BIOSYSTEMS, INC. |
Lab-on-a-Film Multiplexed Test for Respiratory Mycobacterial Infections |
COONEY, CHRISTOPHER GERARD |
NIAID |
FREDERICK |
MD |
31-July-2025 |
| REMBAC ENVIRONMENTAL, LLC |
Development of an innovative approach for in situ treatment of PCB impacted sediments by microbial bioremediation |
AMOS, CRAIG BENNETT |
NIEHS |
ELLICOTT CITY |
MD |
31-July-2025 |
| SIRPANT IMMUNOTHERAPEUTICS, INC. |
SIRPant Technology for anti-Cancer Immunity |
MCCURLEY, NATHANAEL |
NCI |
CHAMBERSBURG |
PA |
31-July-2025 |
| PARAMETRIC STUDIO, INC. |
A Virtual Project-Based Learning Sandbox for Mimetics and Medically Inspired Classroom Engineering (MiMICRE) |
WHITMER, CHRISTOPHER ELDON |
NIGMS |
AMES |
IA |
31-July-2025 |
| NEPHSMART LLC |
A Device for Detection of Acute Kidney Injury |
ARTHUR, JOHN M. |
NIDDK |
LITTLE ROCK |
AR |
31-July-2025 |
| AQUALUNG THERAPEUTICS CORP. |
Targeting the eNAMPT/TLR4 pathway to reduce Inflammatory Bowel Disease severity |
GARCIA, JOE G. N. |
NIDDK |
Juno Beach |
FL |
31-July-2025 |
| MANDALMED, INC. |
Cell-based Gene Therapy for MPS IVA |
MOUNZIH, KHALID |
NIAMS |
SAN FRANCISCO |
CA |
31-July-2025 |
| KELIOMICS, INC. |
Engineering ex vivo breast tumors in human breast tissue to address racial disparities in HR-/ERBB2+ breast cancer |
LAU, FRANK |
NCI |
PORTLAND |
OR |
31-July-2025 |
| SENAPTEC INC. |
Development of an In-Home Sensory Training Therapy to Mitigate Falls Risk Among the Elderly |
YOO, HERBERT |
NIA |
Beaverton |
OR |
31-July-2025 |
| NYTRICX INC. |
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-July-2025 |
| ABBRATECH, INC. |
Method for the validation by Western analysis of affinity reagents against post-translationally modified proteins. |
WEINER, MICHAEL P |
NIGMS |
Branford |
CT |
31-July-2025 |
| MAGNETIC INSIGHT, INC. |
Ultra-low distortion and noise electronics to enable a clinical MPI imaging platform |
GOODWILL, PATRICK |
NIBIB |
Alameda |
CA |
31-July-2025 |
| GRANITE MEDICAL, LLC |
Non-invasively extendable megaprosthesis |
GORDON, JEFFREY DAVID |
NIAMS |
HANOVER |
NH |
31-July-2025 |
| KINETIQ THERAPEUTICS LLC |
Evaluating a Novel Enzymatic Modality for the Treatment of Fanconi Anemia |
CAO, MINGJU |
NHLBI |
FORT WORTH |
TX |
31-July-2025 |
| NOSTOPHARMA, LLC |
Small molecules combination therapy using polypharmacology approach as a novel treatment paradigm for rare bone disease |
JEREMIC, JELENA GVOZDENOVIC |
NCATS |
POTOMAC |
MD |
31-July-2025 |
| BIOKIER, INC. |
Clinical development of a colon-targeted butyrate tablet to evaluate effects on cholesterol and trimethyl amine oxide in subjects at risk for cardiovascular disease |
SZEWCZYK, JERZY |
NHLBI |
CHAPEL HILL |
NC |
31-July-2025 |
| NOVAGYN LLC |
Natural Electrospun Scaffolds as an Alternative to Synthetic Mesh for Stress Urinary Incontinence |
THOMSON, REBECCA |
NIDDK |
HOPKINTON |
NH |
31-July-2025 |
| UNANDUP, LLC |
An Improved Robotic Electrophysiology Platform for Arrhythmia Ablation |
CREIGHTON, FRANCIS MILTON |
NHLBI |
SAINT LOUIS |
MO |
31-July-2025 |
| APOGEE BIOTECHNOLOGY CORPORATION |
Opaganib as a Medical Countermeasure for Gastrointestinal Acute Radiation Syndrome |
SMITH, CHARLES D |
NIAID |
HUMMELSTOWN |
PA |
31-July-2025 |
| TEZCAT LABORATORIES LLC |
A novel monobody-drug conjugate to treat mutant Ras multiple myeloma |
RAMIREZ, CRAIG PATRICK |
NCI |
New Haven |
CT |
31-July-2025 |
| LEAFLABS, LLC |
Untethered high channel count electrophysiology for freely-moving animals |
SHERWOOD, JOHN L |
NIMH |
CAMBRIDGE |
MA |
31-July-2025 |
| CORTECHS LABS, INC. |
RSI-AI: Predicting clinically significant prostate cancer to guide biopsy decisions by combining advanced tissue microstructure imaging with deep learning |
WHITE, NATHAN SCOTT |
NCI |
San Diego |
CA |
31-July-2025 |
| LAMPROGEN, INC. |
An expanded 75-color panel of Pdots for spectral multiplexing |
YU, JIANGBO |
NIGMS |
SEATTLE |
WA |
31-July-2025 |
| QUANTITATIVE BIOSCIENCES, INC. |
CLEdgeSeq: Advanced sequence analysis and communication for edge applications |
MATHER, WILLIAM |
NIGMS |
San Diego |
CA |
31-July-2025 |
| SIGMOVIR BIOSYSTEMS, INC. |
Inducible HMGB1 antagonist for viral-induced acute lung injury. |
BLANCO, JORGE C |
NHLBI |
ROCKVILLE |
MD |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| FLUID SYNCHRONY, LLC |
Wirelessly controlled BSL3 vivarium system for automated microdosing in studies of infectious diseases |
HOANG, TUAN Q |
OD |
PASADENA |
CA |
31-July-2025 |
| SONOVOL, INC. |
A turnkey research platform to accelerate clinical translation of targeted immune-modulation enhanced therapies |
GESSNER, RYAN |
NCI |
Durham |
NC |
31-July-2025 |
| BIOPTICSTECHNOLOGY, LLC |
High-density optical tomography of cerebral blood flow and metabolism in small animals |
YU, GUOQIANG |
NINDS |
LEXINGTON |
KY |
31-July-2025 |
| POLYNOVA CARDIOVASCULAR, INC |
A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement |
BLUESTEIN, DANNY |
NHLBI |
STONY BROOK |
NY |
31-July-2025 |
| ELDEC PHARMACEUTICALS, INC. |
Novel Peptide Fusion Inhibitors for the Treatment of COVID-19 |
TARRAN, ROBERT |
NIAID |
Durham |
NC |
31-July-2025 |
| DISCIDIUM BIOSCIENCES, LLC |
Simple Method for Screening of HIV Drug Resistance in Resource-Limited Settings |
STEVENSON, MARIO |
NIAID |
MIAMI |
FL |
31-July-2025 |
| CROSSLIFE TECHNOLOGIES, INC. |
Rapid Point-of-Care RNA Diagnostic for Dengue Infection |
CHO, HYUNDAE |
NIAID |
CARLSBAD |
CA |
31-July-2025 |
| DAY ZERO DIAGNOSTICS, INC. |
EpiXact-FMT: A metagenomic, pharmacovigilance assay for microbiota therapeutics safety |
SATER, MOHAMAD |
NIAID |
Boston |
MA |
31-July-2025 |
| OLIGOMERIX, INC |
GMP Production of a Tau Oligomer Inhibitor to Enable Clinical Development forADRD |
MOE, JAMES G. |
NIA |
White Plains |
NY |
31-July-2025 |
| NYTRICX INC. |
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-July-2025 |
| GAMMA THERAPEUTICS, INC. |
Development of Antisense Oligonucleotides to Regulate Gamma' Fibrinogen Levels |
FARRELL, DAVID HENRY |
NHLBI |
PORTLAND |
OR |
31-July-2025 |
| REELIN THERAPEUTICS, INC. |
Effect of APP copy number variants in Alzheimer's disease and and Down Syndrome on Reelin expression and function |
KOUNNAS, MARIA Z |
NIA |
SAN DIEGO |
CA |
31-July-2025 |
| NANITE INC. |
Computationally-Inspired Design of Non-Viral Gene Delivery Vehicles for mRNA-Based Cystic Fibrosis Therapies |
MURTHY, SHASHI |
NHLBI |
WATERTOWN |
MA |
31-July-2025 |
| REMBAC ENVIRONMENTAL, LLC |
Development of an innovative approach for in situ treatment of PCB impacted sediments by microbial bioremediation |
AMOS, CRAIG BENNETT |
NIEHS |
ELLICOTT CITY |
MD |
31-July-2025 |
| LIGHT SWITCH BIO, LLC |
Light-directed therapy of squamous cell head and neck cancer with a novel dual-acting chemotherapeutic. |
HARTMAN, MATTHEW C |
NCI |
Richmond |
VA |
31-July-2025 |
| ELEVATEU |
A Novel Platform to Identify and Treat Transitional Age Youth With Alcohol Use Disorder |
GARETT, RENEE |
NIAAA |
LOS ANGELES |
CA |
31-July-2025 |
| LEAFLABS, LLC |
Untethered high channel count electrophysiology for freely-moving animals |
SHERWOOD, JOHN L |
NIMH |
CAMBRIDGE |
MA |
31-July-2025 |
| SIOLTA THERAPEUTICS, INC. |
A Synergistic Multistrain Live Biotherapeutic Product for the Prevention and Treatment of Necrotizing Enterocolitis |
VALLADARES, RICARDO |
NIAID |
SAN CARLOS |
CA |
31-July-2025 |
| COUPLET CARE, LLC |
Development of the Couplet Care Bassinet to support safe implementation of skin-to-skin contact and rooming-in on postnatal units |
MCENTYRE, STACIE |
NICHD |
Apex |
NC |
31-July-2025 |
| CAPSULOMICS, LLC |
Validation and Early Commercialization of the ENVISAGE Assay, a Prognostic Test for Barrett's Esophagus |
LAUN, SARAH |
NIDDK |
Baltimore |
MD |
31-July-2025 |
| PURE GREEN PHARMACEUTICALS, INC. |
Cannabidiol/Palmitoylethanolamide sublingual tablets for the treatment of Painful Diabetic Peripheral Neuropathy |
KIMLESS, DEBRA |
NIDDK |
WEST BLOOMFIELD |
MI |
31-July-2025 |
| MAGNETIC INSIGHT, INC. |
Ultra-low distortion and noise electronics to enable a clinical MPI imaging platform |
GOODWILL, PATRICK |
NIBIB |
Alameda |
CA |
31-July-2025 |
| PIROUETTE MEDICAL |
A Rugged, Reliable, Portable, Safe, and Simple Naloxone HCl Auto-Injector forLife-Saving Treatment of Opioid Overdose |
CULLINANE, CONOR R |
NIDA |
Portsmouth |
NH |
31-July-2025 |
| HILLHURST BIOPHARMACEUTICALS, INC. |
Low Dose Oral Carbon Monoxide Therapeutic for Virus-Induced Lung Injury |
GOMPERTS, EDWARD |
NIAID |
MONTROSE |
CA |
31-July-2025 |
| PROLOCOR INC. |
Validation of Platelet Expression of FcɣRIIa as a Precision Tool |
OHRNBERGER, JEANNE |
NHLBI |
SHELBURNE |
VT |
31-July-2025 |
| MICROBIOTIX, INC |
Discovery of Bunyaviral Endonuclease Inhibitors for Antiviral Therapy |
LIU, GAI |
NIAID |
WORCESTER |
MA |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| ASPERO MEDICAL, INC. |
Micro-textured balloons with improved traction for better control in endoscopy |
RENTSCHLER, MARK |
NIDDK |
BOULDER |
CO |
31-July-2025 |
| ZYLO THERAPEUTICS, INC. |
Development and optimization of a nitric oxide releasing microparticle-basedtopical treatment for onychomycosis |
DRAGANSKI, ANDREW R |
NIAID |
GREENVILLE |
SC |
31-July-2025 |
| MICROBRIGHTFIELD, LLC |
NeuroExM |
GLASER, JACOB R |
NIMH |
WILLISTON |
VT |
31-July-2025 |
| ALDATU BIOSCIENCES, INC. |
Commercialization of PANDAA qDx for rapid drug resistance genotyping of protease inhibitor ART failures in resource-limited settings. |
MACLEOD, IAIN JAMES |
NIAID |
Watertown |
MA |
31-July-2025 |
| AKONNI BIOSYSTEMS, INC. |
Lab-on-a-Film Multiplexed Test for Respiratory Mycobacterial Infections |
COONEY, CHRISTOPHER GERARD |
NIAID |
FREDERICK |
MD |
31-July-2025 |
| RATIONAL VACCINES, INC. |
Preclinical Evaluation of a Novel Immunomodulatory Vaccine for Preventing and Treating HSV Infections |
GERSHBURG, EDWARD |
NIAID |
Baton Rouge |
LA |
31-July-2025 |
| PIONEER NEUROTECH INC. |
Controlled Gradient Release of Biologics: Enhanced Nerve Conduit for Long‐Gap Injury Repair |
ROMERO-ORTEGA, MARIO IGNACIO |
NINDS |
SUDBURY |
MA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| FAKNOSTICS, LLC |
Development of Non-Catalytic Peptide Inhibitors of Focal Adhesion Kinase (FAK) for Use in Melanoma |
MARLOWE, TIMOTHY A |
NCI |
PHOENIX |
AZ |
31-July-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Novel Pediatric Endotracheal Tube Securement System |
RYDBERG, NICK |
NICHD |
SAINT PAUL |
MN |
31-July-2025 |
| KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT |
Portable Noninvasive Positive Airway Device for COPD Patient Therapy |
KNUESEL, ROBERT J |
NHLBI |
Minneapolis |
MN |
31-July-2025 |
| CPR THERAPEUTICS, INC. |
A Multimodal Integrated System For Improved Cardiopulmonary Resuscitation |
PARADIS, NORMAN ALAN |
NHLBI |
PUTNEY |
VT |
31-July-2025 |
| METIS HEALTH ANALYTICS, LLC |
Quality and Safety Monitoring of Clinical Computed Tomography Practice |
SAPP, ARMISTEAD WRIGHT |
NIBIB |
DURHAM |
NC |
31-July-2025 |
| CYTEX THERAPEUTICS INC. |
Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model |
ESTES, BRADLEY T |
NIAMS |
DURHAM |
NC |
31-July-2025 |
| ADVANCED COOLING THERAPY, LLC |
Utility of Esophageal Cooling Therapy for the Prevention of Thermal Injury During Atrial Fibrillation |
KULSTAD, ERIK BENJAMIN |
NHLBI |
Chicago, IL |
IL |
31-July-2025 |
| HIBAR MICROSCIENCES, LLC |
Enhanced renal dialysis membrane performance using lipocalin modified substrates |
TUMLIN, JAMES A |
NIDDK |
ATLANTA |
GA |
31-July-2025 |
| NOTA LABORATORIES, LLC |
Photochemical Generation of Gas Phase Nitric Oxide from Immobilized S-Nitrosothiols for Biomedical Applications |
WOLF, ALEXANDER KEITH |
NHLBI |
ANN ARBOR |
MI |
31-July-2025 |
| ALTIS BIOSYSTEMS, INC. |
A 2D Intestinal Crypt Platform for Compound Screens |
SIMS, CHRISTOPHER ELDRIDGE |
NIDDK |
Durham |
NC |
31-July-2025 |
| POSIT SCIENCE CORPORATION |
Remote STATE training for Insomnia in Older Adults |
VANVLEET, THOMAS |
NIA |
SAN FRANCISCO |
CA |
31-July-2025 |
| FIBROBIOLOGICS, LLC |
Preclinical Development of a Novel Therapeutic Agent for Idiopathic Pulmonary Fibrosis |
BOGATKEVICH, GALINA S |
NHLBI |
CHARLESTON |
SC |
31-July-2025 |
| HAIRDAYS, INC. |
Knowledge Engine- A computational approach to combatting dermatological health disparities in underserved communities |
ST. BERNARD, TIFFANY |
NIMHD |
ITHACA |
NY |
31-July-2025 |
| MILLION MARKER WELLNESS INC. |
A Personalized Digital Intervention Program to Reduce Exposure to Endocrine Disrupting Chemicals among a Child-Bearing Age Cohort |
HUA, JENNA |
NIEHS |
EL CERRITO |
CA |
31-July-2025 |
| NEONEUR LLC |
Improving high-risk infant care: from Hospital to Home with Neoneur Telehealth |
HOEDEMAKER, CAROLINE |
NINR |
PENNINGTON |
NJ |
31-July-2025 |
| AMIDEBIO, LLC |
Long-acting Stable Glucagons for Treatment of Hyperinsulinism |
FLUDZINSKI, PAWEL |
NIDDK |
LOUISVILLE |
CO |
31-July-2025 |
| WEATHERWAX BIOTECHNOLOGIES CORPORATION |
Development of Heterobivalent Small-Molecule Therapeutics for the Treatment of Triple-Negative Breast Cancer |
COGNETTA, ARMAND |
NCI |
SAN FRANCISCO |
CA |
31-July-2025 |
| GRANITE MEDICAL, LLC |
Non-invasively extendable megaprosthesis |
GORDON, JEFFREY DAVID |
NIAMS |
HANOVER |
NH |
31-July-2025 |
| SERENTRIX, LLC |
Topical treatment for burn pain by blocking cutaneous pain receptors. |
BHARGAVA, KUMARIL |
NIGMS |
EXTON |
PA |
31-July-2025 |
| NYTRICX INC. |
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| DUO ONCOLOGY INC |
Stroma-penetrating nanomedicine to improve treatment for pancreatic cancer |
EICHINGER, KATHERINE MARIE |
NCI |
PITTSBURGH |
PA |
31-July-2025 |
| ATTAGENE, INC. |
Assigning mode of action to phenotypically discovered anticancer leads. |
MAKAROV, SERGEI S |
NCI |
RESEARCH TRIANGLE PARK |
NC |
31-July-2025 |
| SPOC PROTEOMICS INC. |
Development of a chemical reaction sensor array platform for label-free, real-time kinetic analysis of enzyme-substrate reactions to enable high-throughput drug discovery |
TAKULAPALLI, BHARATH |
NCATS |
SCOTTSDALE |
AZ |
31-July-2025 |
| RADIANT CREATIVE GROUP, LLC |
Agile development of innovative, interactive hazard recognition and mitigation tools/learning e-platforms for workers involved in disaster rescue and recovery. |
MCLAUGHLIN, JEFFERY |
NIEHS |
HOUSTON |
TX |
31-July-2025 |
| COOLER HEADS CARE INC |
Portable, Patient-Administered Scalp Cooling Cap to Reduce Provider Burden, Improve Patient Access, and Improve Patient Outcomes for Chemotherapy-Induced Alopecia |
DILLIGAN, KATE |
NCI |
SAN DIEGO |
CA |
31-July-2025 |
| FZATA, INC. |
A Serological Assay for Neutralizing Antitoxin Response in Patients with Clostridioides difficile Infection (Phase II) |
YANG, ZHIYONG |
NIAID |
HALETHORPE |
MD |
31-July-2025 |
| RESILIENT GAMES STUDIO, LLC |
Step UP for STEM and Health Careers: An Intervention to Reduce STEM-related biases and improve high school STEM learning environments |
PARSONS, TIMOTHY |
NICHD |
Chicago |
IL |
31-July-2025 |
| NEW MEXICO START-UP FACTORY II, LLC |
Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States |
CHAVEZ, JOHN |
NIGMS |
ALBUQUERQUE |
NM |
31-July-2025 |
| GLYCOMANTRA, INC. |
Targeting galectin-3 to intervene COVID-19 |
AHMED, HAFIZ |
NIAID |
LEESBURG |
VA |
31-July-2025 |
| NAMI THERAPEUTICS CORP. |
Nanoparticle-based Intraperitoneal Delivery of Combined Chemo-radiotherapy for Treatment of Ovarian Cancer Metastases |
JAY, MICHAEL |
NCI |
STORRS |
CT |
31-July-2025 |
| AUTOIMMUNITY BIOLOGIC SOLUTIONS, INC. |
Development of a novel accurate therapy for multiple sclerosis |
GALARZA-MUNOZ, GADDIEL |
NIAID |
Galveston |
TX |
31-July-2025 |
| IT BIO, LLC |
Advanced generation infection-proof anti-HIV CAR-T with YY1 RNAi to block T cell exhaustion in NHP model |
JUNGHANS, RICHARD P |
NIAID |
BOSTON |
MA |
31-July-2025 |
| OPEN EPHYS, INC |
ONIX: A Neural Acquisition System for Unencumbered, Closed-Loop Recordings in Small, Freely Moving Animals |
NEWMAN, JONATHAN |
NINDS |
CAMBRIDGE |
MA |
31-July-2025 |
| TING THERAPEUTICS, INC. |
Preclinical evaluation of an otoprotectant TT002 |
HUANG, YUNLONG |
NIDCD |
OMAHA |
NE |
31-July-2025 |
| IMMUTO SCIENTIFIC, INC. |
Plasma-Generated Hydroxyl Radicals for Analysis of Three-Dimensional Structures in Protein Therapeutics |
CHOUDHURY, FARAZ |
NIGMS |
MADISON |
WI |
31-July-2025 |
| PETCOIL, INC. |
A Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging |
CHANG, CHENMING |
NIMH |
Sunnyvale |
CA |
31-July-2025 |
| LYSSN.IO, INC. |
Enhancing the quality of CBT in community mental health through AI-generated fidelity feedback |
ATKINS, DAVID CHARLES |
NIMH |
SEATTLE |
WA |
31-July-2025 |
| COLLABORATIONS PHARMACEUTICALS, INC. |
MegaTox for analyzing and visualizing data across different screening systems |
EKINS, SEAN |
NIEHS |
FUQUAY VARINA |
NC |
31-July-2025 |
| BLACKROCK MICROSYSTEMS |
High density chronic optogenetic interface for primate brains |
NEGI, SANDEEP |
NIMH |
SALT LAKE CITY |
UT |
31-July-2025 |
| SPREADING ACTIVATION TECHNOLOGIES, LLC |
Suicide, depression, and anxiety screening using an automated virtual assistant |
COHEN, JOSHUA |
NIMH |
MASON |
OH |
31-July-2025 |
| PSY THERAPEUTICS, INC. |
Development of brain-penetrant COMT inhibitors for the treatment of depressive disorders |
CROSS, ALAN J. |
NIMH |
WALTHAM |
MA |
31-July-2025 |
| ADHERA HEALTH, INC. |
Adaptation of a Digital Health Intervention for Chronic Condition Related fatigue to the Latino population |
FERNANDEZ LUQUE, LUIS |
NIMHD |
PALO ALTO |
CA |
31-July-2025 |
| MEDOSOME BIOTEC, LLC |
Engineering next generation probiotics for delivery of therapeutics |
WAGNER, RICHARD |
NCATS |
Alachua |
FL |
31-July-2025 |
| UNANDUP, LLC |
An Improved Robotic Electrophysiology Platform for Arrhythmia Ablation |
CREIGHTON, FRANCIS MILTON |
NHLBI |
SAINT LOUIS |
MO |
31-July-2025 |
| BIOPAC SYSTEMS, INC. |
Temperature-Controlled Recording System for Wireless Data Acquisition from Immature Rodents |
ROWE, MANOEL |
NIMH |
GOLETA |
CA |
31-July-2025 |
| RUSH RIVER RESEARCH CORPORATION |
Auto-Titrating Oral Appliance for Sleep Disordered Breathing |
LUNDSTROM, JULIE |
NHLBI |
ELLSWORTH |
WI |
31-July-2025 |
| POISERA, INC. |
Identifying and Addressing Social Determinants of Health in Pregnant Women |
KERPPOLA, MARIANNA |
NIMHD |
ANN ARBOR |
MI |
31-July-2025 |
| MIDWEST BIOPROCESSING CENTER, LLC |
Production of Natural Deoxysugars for Use in Chemical Synthesis of Glycosides |
TURNER, ROBERT J. |
NIGMS |
Peoria |
IL |
31-July-2025 |
| AURICLE HEALTH INC |
Development of an Extracochlear Device to Restore Hearing |
WONG, FRANCIS |
NIDCD |
OAKLAND |
CA |
31-July-2025 |
| REMASTERED SLEEP LLC |
Novel Myofunctional Therapy Water Bottle to Reduce Obstructive Sleep Apnea and Snoring |
OLMANSON, ANDERS |
NHLBI |
EAGAN |
MN |
31-July-2025 |
| THERANOVA, LLC |
A Novel Orogastric/Nasogastric Feeding Tube for Optimizing Nutritional Administration in the Neonatal Intensive Care Unit Population |
BURNETT, DANIEL ROGERS |
NICHD |
SAN FRANCISCO |
CA |
31-July-2025 |
| APOGEE BIOTECHNOLOGY CORPORATION |
Opaganib as a Medical Countermeasure for Gastrointestinal Acute Radiation Syndrome |
SMITH, CHARLES D |
NIAID |
HUMMELSTOWN |
PA |
31-July-2025 |
| SYNAPTICURE, INC. |
Mature brain organoid platform for therapeutic screening for ALS/FTD |
GHAFFARI, LAYLA |
NINDS |
KENILWORTH |
IL |
31-July-2025 |
| FESARIUSTHERAPEUTICS, INC. |
An Advanced Dermal Regeneration Scaffold for Reconstructive Surgery |
SAPIR LEKHOVITSER, YULIA |
NIAMS |
NEW YORK |
NY |
31-July-2025 |
| QUA, INC. |
Development and Evaluation of the PPAL Bedside Commode for Safe Independent Toileting Transfers |
GRAHAM, MARGARET ELLEN |
NINR |
NEW ROCHELLE |
NY |
31-July-2025 |
| URBAN DESIGN 4 HEALTH, INC. |
PED-PHAM: An Automated and Scalable Spatial Tool That Predicts and Monetizes Health Impacts of the Built, Natural, and Social Environment |
CHAPMAN, JAMES |
NHLBI |
ROCHESTER |
NY |
31-July-2025 |
| AQUALUNG THERAPEUTICS CORP. |
Targeting the eNAMPT/TLR4 pathway to reduce Inflammatory Bowel Disease severity |
GARCIA, JOE G. N. |
NIDDK |
Juno Beach |
FL |
31-July-2025 |
| NANOHMICS, INC. |
Ambulatory cryocooling therapy device |
SAVOY, STEVE MICHAEL |
NIAMS |
AUSTIN |
TX |
31-July-2025 |
| VIVOVERSE, LLC |
The Next-Generation Developmental and Reproductive Toxicology (DART) Assay using High-Content Analysis of Genetically Diverse C. elegans Populations |
HEGARTY, EVAN |
NIEHS |
AUSTIN |
TX |
31-July-2025 |
| BERKSHIRE BIOMEDICAL CORPORATION |
COPA, an Automated Medication Dispensing and Remote Management System for at Home Methadone Dispensing |
TIMBERLAKE, JOHN |
NIDA |
DALLAS |
TX |
31-July-2025 |
| MEDICAL PREDICTIVE SCIENCE CORPORATION |
Clinical Decision Support System to Optimize Neonatal Nutrition and Growth |
KING, WILLIAM E |
NICHD |
CHARLOTTESVILLE |
VA |
31-July-2025 |
| BIOINVISION, INC. |
System-independent quantitative cardiac CT perfusion |
ROY, DEBASHISH |
NHLBI |
CLEVELAND |
OH |
31-July-2025 |
| TF HEALTH CORPORATION |
Smart driving technology for non-invasive detection of age-related cognitive decline |
TSOW, FRANCIS |
NIA |
FOUNTAIN HILLS |
AZ |
31-July-2025 |
| OPALGENIX, INC. |
Reducing Opioid Use and Adverse Effects through Proactive Precision Pain Management Following Spine Surgery |
PLUMP, STEVEN R. |
NIDA |
INDIANAPOLIS |
IN |
31-July-2025 |
| BRIGHT URO, INC. |
Clinical Feasibility of Wireless Catheter-Free Urodynamics for Extended, Comprehensive Urological Evaluation in the Home Setting |
HERRERA, DEREK |
NIDDK |
Irvine |
CA |
31-July-2025 |
| AINCOBIO LLC |
Rapid and automated detection of bloodborne pathogens for improved treatment and antimicrobial stewardship |
DAMICO, LORENZO |
NIAID |
Syracuse |
NY |
31-July-2025 |
| TRESTLE OPTICS LLC |
Ultra-broadband multimodal microscopy with a catadioptric lens |
HANNINEN, ADAM M |
NIGMS |
IRVINE |
CA |
31-July-2025 |
| YAYA SCIENTIFIC, LLC |
Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View |
BABA, JUSTIN |
NIBIB |
Nashville |
TN |
31-July-2025 |
| BEHAVR, LLC |
Digital Therapeutic Development of Virtual Cognitive-Affective Training for Opioid Use Disorder |
WEISBERG, RISA B |
NIDA |
ELIZABETHTOWN |
KY |
31-July-2025 |
| PIONEER NEUROTECH INC. |
Controlled Gradient Release of Biologics: Enhanced Nerve Conduit for Long‐Gap Injury Repair |
ROMERO-ORTEGA, MARIO IGNACIO |
NINDS |
SUDBURY |
MA |
31-July-2025 |
| EPICYPHER, INC. |
Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cells |
KEOGH, MICHAEL-CHRISTOPHER |
NIAID |
Research Triangle Park |
NC |
31-July-2025 |
| HABITAWARE, INC. |
Technology Assisted Treatment for Binge Eating Behavior |
KUMAR, SAMEER |
NIMH |
Minneapolis |
MN |
31-July-2025 |
| TRETHERA CORPORATION |
Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Acute Disseminated Encephalomyelitis (ADEM) |
SCHULTZ, KENNETH |
NIAID |
SHERMAN OAKS |
CA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| FESARIUSTHERAPEUTICS, INC. |
An Advanced Dermal Regeneration Scaffold for Reconstructive Surgery |
SAPIR LEKHOVITSER, YULIA |
NIAMS |
NEW YORK |
NY |
31-July-2025 |
| COVE TECHNOLOGY CONSULTING LLC |
A closed-loop gravity infusion control device |
KAWAHARA, CHIE |
NINR |
BAINBRIDGE ISLAND |
WA |
31-July-2025 |
| RISE THERAPEUTICS, LLC |
A Novel Immunological-Directed Live Biotherapy Product for Treating Ulcerative Colitis |
FANGER, GARY |
NIDDK |
Rockville |
MD |
31-July-2025 |
| VIVOVERSE, LLC |
The Next-Generation Developmental and Reproductive Toxicology (DART) Assay using High-Content Analysis of Genetically Diverse C. elegans Populations |
HEGARTY, EVAN |
NIEHS |
AUSTIN |
TX |
31-July-2025 |
| BERKSHIRE BIOMEDICAL CORPORATION |
COPA, an Automated Medication Dispensing and Remote Management System for at Home Methadone Dispensing - Administrative Supplement |
TIMBERLAKE, JOHN |
NIDA |
DALLAS |
TX |
31-July-2025 |
| ACURASTEM, INC. |
Development of a SYF2 antisense oligonucleotide treatment for ALS and FTD |
ALWORTH, SAMUEL V |
NIA |
Monrovia |
CA |
31-July-2025 |
| AAVOGEN, INC. |
Development of optimized adeno-associated viral capsids for muscle gene therapy |
RODGERS, BUEL |
NIAMS |
ROCKVILLE |
MD |
31-July-2025 |
| LYSSN.IO, INC. |
Enhancing the quality of CBT in community mental health through AI-generated fidelity feedback |
ATKINS, DAVID CHARLES |
NIMH |
SEATTLE |
WA |
31-July-2025 |
| OLIGOMERIX, INC |
GMP Production of a Tau Oligomer Inhibitor to Enable Clinical Development forADRD |
MOE, JAMES G. |
NIA |
White Plains |
NY |
31-July-2025 |
| TISSUEVISION, INC. |
A high throughput multiplexed pipeline for models of Alzheimer’s Disease |
RAGAN, TIMOTHY M. |
NIA |
Newton |
MA |
31-July-2025 |
| PROKARYOTICS, INC. |
Development of a novel broad spectrum antifungal therapeutic targeting Glycosylphosphatidylinositol (GPI) biosynthesis and cell wall biogenesis |
ROEMER, TERRY |
NIAID |
UNION |
NJ |
31-July-2025 |
| COUPLET CARE, LLC |
Development of the Couplet Care Bassinet to support safe implementation of skin-to-skin contact and rooming-in on postnatal units |
MCENTYRE, STACIE |
NICHD |
Apex |
NC |
31-July-2025 |
| PSYCHOGENICS, INC. |
Machine Learning Phenotypic De Novo Drug Design |
BRUNNER, DANIELA |
NIMH |
Paramus |
NJ |
31-July-2025 |
| HENLEY ION, LLC |
A micronized electrostatic precipitator for next-generation respiratory protection against pathogenic aerosols |
HENLEY, JULIAN |
NIAID |
Mandeville |
LA |
31-July-2025 |
| MICROBIOTIX, INC |
Development of antibody drug conjugates as pan-filo antivirals |
LIU, GAI |
NIAID |
WORCESTER |
MA |
31-July-2025 |
| CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC |
STARTUP Central |
FRIIS, ELIZABETH A |
NIGMS |
LAWRENCE |
KS |
31-July-2025 |
| SOOVU LABS INC |
Treating stress and anxiety in individuals with alcohol use disorder (AUD) using a combination of TRPV-1 channel and C-tactile fiber activation with measurement of oxytocin and cortisol levels |
CHABAL, CHARLES |
NIAAA |
SEATTLE |
WA |
31-July-2025 |
| OLIPHA INC |
A Biobased Biodegradable Sunscreen that is Safe, Removes Environmental Impact, is Inclusive of all Skin Tones, and is for the Purpose of Eliminating Disparities in Melanoma Mortality Rates |
CAL, ANDREW |
NIMHD |
WILMINGTON |
DE |
31-July-2025 |
| APPLIED UNIVERSAL DYNAMICS CORPORATION |
Smartphone Machine Learning Speech Enhancement System for Hearing Aid Devices for the Underserved and Rural Populations |
GIBSON, PAUL |
NIA |
LORETTO |
MN |
31-July-2025 |
| TRIPILL BIOTECHNOLOGY, CORP. |
The Development of Radiolabeled PSMA Agent with Low Salivary Gland Uptake |
WU, ZHANHONG |
NCI |
CHAPEL HILL |
NC |
31-July-2025 |
| FLEX ORTHOPAEDICS, INC. |
A COMPLIANT ANKLE ENDOPROSTHESIS TO TREAT ANKLE-HINDFOOT PATHOLOGY |
PETERSON, BRANDON |
NIAMS |
CALABASAS |
CA |
31-July-2025 |
| NEW MEXICO START-UP FACTORY II, LLC |
Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States |
CHAVEZ, JOHN |
NIGMS |
ALBUQUERQUE |
NM |
31-July-2025 |
| CARDIAC RSK3 INHIBITORS, LLC |
RSK3 Anchoring Disruptor Therapy for Heart Failure |
CIVIDINI, FEDERICO |
NHLBI |
LOS ALTOS |
CA |
31-July-2025 |
| ORIGAMI THERAPEUTICS, INC. |
Characterization of small molecules that lower mutant huntingtin protein as potential therapeutics for Huntington’s disease |
HOFFMAN, BETH J |
NINDS |
SAN DIEGO |
CA |
31-July-2025 |
| ECLIPSE ORTHOPAEDICS, LLC |
Fluoroscopic drill attachment for orthopedic trauma surgery |
RICH, DAVID BOYD |
NIAMS |
WARSAW |
IN |
31-July-2025 |
| ATTAGENE, INC. |
Assigning mode of action to phenotypically discovered anticancer leads. |
MAKAROV, SERGEI S |
NCI |
RESEARCH TRIANGLE PARK |
NC |
31-July-2025 |
| GOALISTICS, LLC |
Training Psychologists and Nurse Practitioners in the Use of an Evidence-Based Online Pain Self-Management Program: Leveraging the Power of Expert Guidance and Telehealth |
RUEHLMAN, LINDA SUE |
NIMH |
TEMPE |
AZ |
31-July-2025 |
| SIEYAX, LLC |
Preclinical Studies to Develop an Eya2 Tyr Phosphatase Inhibitor as a Novel Medulloblastoma Therapeutic |
FORD, HEIDE L. |
NCI |
BROOMFIELD |
CO |
31-July-2025 |
| XCELLASSAY, INC. |
One-step, in-the-field detection of water contamination by unhealthy concentrations of Endocrine Disrupting Chemicals affecting Nuclear Receptors arrayed on a test strip |
SCHAUFELE, FRED J |
NIEHS |
SAN FRANCISCO |
CA |
31-July-2025 |
| BACKSTOP NEURAL, INC. |
Thin, Softening Epidural Leads for Chronic Arm and Neck Pain |
MANZ, CONNIE |
NINDS |
DALLAS |
TX |
31-July-2025 |
| VOX BIOMEDICAL LLC |
Breath aerosol capture by electric field concentration |
LINDEN, KURT J |
NIDA |
Bedford |
MA |
31-July-2025 |
| IN VIVO ANALYTICS, INC. |
A modular bioluminescence imaging platform using a novel multi-aperture method |
KLOSE, ALEXANDER D. |
NIMH |
NEW YORK |
NY |
31-July-2025 |
| SEE YOURSELF HEALTH, LLC |
The Chiron Project: Using Virtual Reality to Prevent Substance Use Disorder in Healthcare Workers Facing Burnout |
DRASCHER, MAXWELL LEE |
NIDA |
BEVERLY |
MA |
31-July-2025 |
| CELLCHORUS INC. |
LF-TIMING: Large-scale label-free profiling of cell-cell interactions |
BERDEAUX, REBECCA L |
NCATS |
Houston |
TX |
31-July-2025 |
| FESARIUSTHERAPEUTICS, INC. |
An Advanced Dermal Regeneration Scaffold for Reconstructive Surgery |
SAPIR LEKHOVITSER, YULIA |
NIAMS |
NEW YORK |
NY |
31-July-2025 |
| QUA, INC. |
Development and Evaluation of the PPAL Bedside Commode for Safe Independent Toileting Transfers |
GRAHAM, MARGARET ELLEN |
NINR |
NEW ROCHELLE |
NY |
31-July-2025 |
| SANO HEALTHCARE CONSULTANTS, LLC |
Advancing Access to Opiate Care and Treatment through a Novel Liquid Methadone Dispensing Device and SMART Container |
KENDRICK, EDWIN |
NIDA |
CORONA |
CA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| 3RT INNOVATIONS |
Development of a brain penetrating single-chain antibody selectively targeting three repeat tau protein as a new treatment for frontotemporal dementia |
SAITO, ERIN |
NINDS |
MANHATTAN BEACH |
CA |
31-July-2025 |
| SPARK BIOMEDICAL INC |
Delivering Transcutaneous Auricular Neurostimulation to Improve Treatment Retention in Opioid Use Disorder |
KHODAPARAST, NAVID |
NIDA |
FRIENDSWOOD |
TX |
31-July-2025 |
| INNOVATIVE DESIGN LABS, INC. |
An Informatics Platform for Objectively Quantifying Electric Power Wheelchair Usage for those with Alzheimer's Disease, Alzheimer's Disease Related Dementias, and Cognitive Impairments |
BECKER, ADAM |
NIA |
MINNEAPOLIS |
MN |
31-July-2025 |
| AUTOIMMUNITY BIOLOGIC SOLUTIONS, INC. |
Strategy for specific delivery of antisense oligonucleotides to T cells |
GALARZA-MUNOZ, GADDIEL |
NIAID |
Galveston |
TX |
31-July-2025 |
| ACURASTEM, INC. |
Development of a SYF2 antisense oligonucleotide treatment for ALS and FTD |
ALWORTH, SAMUEL V |
NIA |
Monrovia |
CA |
31-July-2025 |
| BLUEWILLOW BIOLOGICS, INC. |
Pre-Clinical Development of a Intranasal Bivalent gD2/gB2 HSV-2 Mucosal Vaccine |
TRABBIC, KEVIN |
NIAID |
ANN ARBOR |
MI |
31-July-2025 |
| KITWARE, INC. |
Imaging biomarkers of severe respiratory infections in premature infants Phase II |
LINGURARU, MARIUS GEORGE |
NHLBI |
CLIFTON PARK |
NY |
31-July-2025 |
| SIGMOVIR BIOSYSTEMS, INC. |
Inducible HMGB1 antagonist for viral-induced acute lung injury. |
BLANCO, JORGE C |
NHLBI |
ROCKVILLE |
MD |
31-July-2025 |
| KATHERA BIOSCIENCE INC. |
A Redesigning Existing Drugs against Indispensable Targets (ReEDIT) platform technology for discovery of novel drugs to treat fungal infections |
PARENT, STEPHEN |
NIAID |
UNION |
NJ |
31-July-2025 |
| BIOSYNESIS, INC. |
Development of protease activity-based detector substrates for diagnosing Candida infections |
LOHSE, MATTHEW B. |
NIAID |
SAN FRANCISCO |
CA |
31-July-2025 |
| BEHAVR, LLC |
Digital Therapeutic Development of Virtual Cognitive-Affective Training for Opioid Use Disorder |
WEISBERG, RISA B |
NIDA |
ELIZABETHTOWN |
KY |
31-July-2025 |
| PROTEIOS TECHNOLOGY, INC. |
Simple and Effective Method for Cell Separation During Preclinical Research and Cell Therapy Manufacturing |
SNYDER, BOB |
NIGMS |
ISSAQUAH |
WA |
31-July-2025 |
| EQUITI FOODS, LLC |
Good Bowls: Empowering Communities to Achieve Good Food Access and Health Equity |
AMMERMAN, ALICE S |
NIMHD |
CHAPEL HILL |
NC |
31-July-2025 |
| ELDEC PHARMACEUTICALS, INC. |
Novel Strategies to Clear Bacteria from the CF Lung |
AHMAD, SAIRA |
NHLBI |
Durham |
NC |
31-July-2025 |
| PHOTOSOUND TECHNOLOGIES, INC. |
Integrated photoacoustic and fluorescence imaging system for anatomical, functional, and molecular characterization of murine models |
BRECHT, HANS-PETER FRANZ |
OD |
HOUSTON |
TX |
31-July-2025 |
| ALAUNUS BIOSCIENCES, INC. |
Development of a multi-analyte diagnostic assay to improve the risk stratification of indeterminate thyroid nodules |
KNUDSEN, GISELLE M |
NCI |
NOVATO |
CA |
31-July-2025 |
| AJK BIOPHARMACEUTICAL LLC |
Development of Broad-Spectrum Cyclic Amphiphilic Peptides against Multidrug-Resistant Bacteria |
KAZEMINY, ASSAD |
NIAID |
MISSION VIEJO |
CA |
31-July-2025 |
| BIVACOR, INC. |
Urgent and unmet need for a long-term solution for increasing pediatric heart-failure population: BiVACOR Rotary Total Artificial Heart |
TIMMS, DANIEL |
NHLBI |
HOUSTON |
TX |
31-July-2025 |
| K MEDICAL LLC |
Multi-Stable Compliant-Mechanism-Based Mattress for Bedsore Prevention |
SHETH, PIYUSH KIRANRAI |
NINR |
PORTER RANCH |
CA |
31-July-2025 |
| ADM DIAGNOSTICS, INC. |
Multi-modal machine learning detection and tracking of traumatic brain injury neurodegeneration and its differentiation from Alzheimer's disease |
LUKIC, ANA S |
NIA |
NORTHBROOK |
IL |
31-July-2025 |
| ADVANCED GENE TRANSFER COMPANY, INC. |
Enhanced CRISPR gene editing in pluripotent stem cells using carbon nanotube arrays |
DICKERSON, IAN M |
NIGMS |
ROCHESTER |
NY |
31-July-2025 |
| BARRON ASSOCIATES, INC. |
Respiratory Oxygen Adherence Monitor for COPD Patients |
KREPKOVICH, EILEEN T. |
NHLBI |
CHARLOTTESVILLE |
VA |
31-July-2025 |
| MYOFINITY BIOSCIENCES INC |
Translational development of novel CRISPR approach to treat genomic duplications |
LEK, MONKOL |
NIAMS |
BOSTON |
MA |
31-July-2025 |
| PRO-CHANGE BEHAVIOR SYSTEMS, INC. |
Beat Extreme: An Interactive, Tailored Text Messaging Program Combining Extreme Weather Alerts with Hyper-localized Resources & Actionable Insights for Addressing Climate Change |
JOHNSON, SARA S |
NIEHS |
Narragansett |
RI |
31-July-2025 |
| POP BIOTECHNOLOGIES, INC |
Interstitial Chemophototherapy with Light-Activated Nanoparticulate Doxorubicin |
SHAFIRSTEIN, GAL |
NCI |
BUFFALO |
NY |
31-July-2025 |
| VORTEX BIOTECHNOLOGY CORPORATION |
Regulation of RNA Decapping and Degradation: A novel approach to prostate cancer therapy |
KRAFT, ANDREW S |
NCI |
CHARLESTON |
SC |
31-July-2025 |
| AAVOGEN, INC. |
Development of optimized adeno-associated viral capsids for muscle gene therapy |
RODGERS, BUEL |
NIAMS |
ROCKVILLE |
MD |
31-July-2025 |
| STINGINN, LLC |
Human specific STING agonists for the treatment of cancer |
BARBER, GLEN N |
NCI |
MIAMI |
FL |
31-July-2025 |
| NOSTOPHARMA, LLC |
Small molecules combination therapy using polypharmacology approach as a novel treatment paradigm for rare bone disease |
JEREMIC, JELENA GVOZDENOVIC |
NCATS |
POTOMAC |
MD |
31-July-2025 |
| PROKARYOTICS, INC. |
Development of a novel broad spectrum antifungal therapeutic targeting Glycosylphosphatidylinositol (GPI) biosynthesis and cell wall biogenesis |
ROEMER, TERRY |
NIAID |
UNION |
NJ |
31-July-2025 |
| OYAGEN, INC. |
High throughput screening and drug discovery for antagonists of the Ebola VP40 protein assembly |
SALTER, JASON DOUGLAS |
NIAID |
ROCHESTER |
NY |
31-July-2025 |
| LYNNTECH, INC. |
An Isothermal Method to Amplify RNA from Bloodborne Viruses |
GORZELNIK, KARL |
NIAID |
COLLEGE STATION |
TX |
31-July-2025 |
| LUMINARY THERAPEUTICS, INC. |
Allogeneic BAFF Ligand Based CAR T-Cells as a Novel Therapy for Systemic Lupus Erythematous |
GIBBONS, HUNTER RAMSDELL |
NIAID |
MINNEAPOLIS |
MN |
31-July-2025 |
| TDA RESEARCH, INC. |
Filtration Media for In-Home PFAS Removal from Drinking Water |
DIETZ, STEVEN D |
NIEHS |
GOLDEN |
CO |
31-July-2025 |
| COLLAMEDIX INC. |
OsTend: A load-bearing, bi-phasic collagen scaffold for massive rotator cuff repairs |
SHANKAR, SUBBA |
NIAMS |
CLEVELAND |
OH |
31-July-2025 |
| RADIATION DETECTION TECHNOLOGIES, INC. |
The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications. |
MONTAG, BENJAMIN |
NIBIB |
MANHATTAN |
KS |
31-July-2025 |
| TARGETSITE THERAPEUTICS CORPORATION |
IL-17A mRNA-targeted oligonucleotide therapeutics in Idiopathic Pulmonary Fibrosis (IPF) |
RAMGOLAM, VINOD SATISCH |
NHLBI |
NEW HAVEN |
CT |
31-July-2025 |
| IGE IMMUNO DIAGNOSTIC SYSTEMS, INC. |
Universal Rapid test for HIV Diagnosis |
MIGUEZ, MARIA-JOSE |
NIAID |
Wellington |
FL |
31-July-2025 |
| BD HOLDING, INC. |
An Improved Epigenetic Algorithm for Guiding Low Dose CT Lung Cancer Screening |
PHILIBERT, ROBERT A |
NCI |
IOWA CITY |
IA |
31-July-2025 |
| PSYCHOGENICS, INC. |
Machine Learning Phenotypic De Novo Drug Design |
BRUNNER, DANIELA |
NIMH |
Paramus |
NJ |
31-July-2025 |
| PLANET BIOTECHNOLOGY, INC. |
Factor H Fc fusions as novel therapeutics for Burkholderia pseudomallei infections |
WYCOFF, KEITH |
NIAID |
HAYWARD |
CA |
31-July-2025 |
| TISSUEVISION, INC. |
A high throughput multiplexed pipeline for models of Alzheimer’s Disease |
RAGAN, TIMOTHY M. |
NIA |
Newton |
MA |
31-July-2025 |
| IMMUNOVA THERAPEUTICS, LLC |
Development of a Therapeutic SAPNANO-ESO Vaccine for Prostate Cancer |
WANG, YICHENG |
NCI |
MONROVIA |
CA |
31-July-2025 |
| ABALONE BIO, INC. |
Therapeutic antibodies for treating liver fibrosis |
SCHWIMMER, LAUREN J. |
NIDDK |
Emeryville |
CA |
31-July-2025 |
| MYOLEX, INC. |
Accurate and rapid assessment of sarcopenia in older adults through electrical impedance myography |
DICKINSON, DAVID P. |
NIA |
Brookline |
MA |
31-July-2025 |
| ONCOSTING LLC |
STING agonist-expressing BCG for bladder cancer |
WALLACH, TODD |
NCI |
BALTIMORE |
MD |
31-July-2025 |
| NANOPIN TECHNOLOGIES, INC. |
Early and accurate diagnosis of pulmonary and extrapulmonary tuberculosis in all patient groups using a circulating pathogen-derived antigen |
TOMBLER, THOMAS W |
NIAID |
New Orleans |
LA |
31-July-2025 |
| Q-CHEM, INC. |
Algorithmic improvements in large scale polarizable QM/MM simulations |
FENG, XINTIAN |
NIGMS |
PLEASANTON |
CA |
31-July-2025 |
| TEZCAT LABORATORIES LLC |
A novel monobody-drug conjugate to treat mutant Ras multiple myeloma |
RAMIREZ, CRAIG PATRICK |
NCI |
New Haven |
CT |
31-July-2025 |
| OPALGENIX, INC. |
Improving Analgesic Effectiveness and Safety with Proactive Precision Pain Management in Thoracic Surgical Patients with Lung Lesions |
PLUMP, STEVEN R. |
NHLBI |
INDIANAPOLIS |
IN |
31-July-2025 |
| CARDIAC RSK3 INHIBITORS, LLC |
RSK3 Anchoring Disruptor Therapy for Heart Failure |
CIVIDINI, FEDERICO |
NHLBI |
LOS ALTOS |
CA |
31-July-2025 |
| PARAMETRIC STUDIO, INC. |
A Virtual Project-Based Learning Sandbox for Mimetics and Medically Inspired Classroom Engineering (MiMICRE) |
WHITMER, CHRISTOPHER ELDON |
NIGMS |
AMES |
IA |
31-July-2025 |
| LAMASSU BIO INC |
Development of a novel small molecule MDM2 inhibitor for innovative sarcoma treatment |
HANNA, GABI |
NCI |
DURHAM |
NC |
31-July-2025 |
| POP BIOTECHNOLOGIES, INC |
Mosaic Display of Multivalent Tau and A-Beta peptides on Immunogenic SNAP Liposomes |
HUANG, WEI-CHIAO |
NIA |
BUFFALO |
NY |
31-July-2025 |
| RISE THERAPEUTICS, LLC |
A Novel Immunological-Directed Live Biotherapy Product for Treating Ulcerative Colitis |
FANGER, GARY |
NIDDK |
Rockville |
MD |
31-July-2025 |
| LITRON LABORATORIES, LTD. |
Modeling the Responsiveness of Sensitive Populations to Genotoxic Agents Using DNA Repair Inhibitors |
DERTINGER, STEPHEN D |
NIEHS |
ROCHESTER |
NY |
31-July-2025 |
| SEE YOURSELF HEALTH, LLC |
TABA for The HOPE App: An Immersive Telehealth Solution for Older Adults with Diabetes |
MITCHELL, SUZANNE |
NIA |
BEVERLY |
MA |
31-July-2025 |
| EQUITI FOODS, LLC |
Good Bowls: Empowering Communities to Achieve Good Food Access and Health Equity |
AMMERMAN, ALICE S |
NIMHD |
CHAPEL HILL |
NC |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| PEACEFULLY, INC. |
A comprehensive web-based program to help advanced cancer patients plan for end of life |
GOOD, JENNIFER |
NINR |
WOODLAND HILLS |
CA |
31-July-2025 |
| IT BIO, LLC |
Advanced generation infection-proof anti-HIV CAR-T with YY1 RNAi to block T cell exhaustion in NHP model |
JUNGHANS, RICHARD P |
NIAID |
BOSTON |
MA |
31-July-2025 |
| IMMUTO SCIENTIFIC, INC. |
Plasma-Generated Hydroxyl Radicals for Analysis of Three-Dimensional Structures in Protein Therapeutics |
CHOUDHURY, FARAZ |
NIGMS |
MADISON |
WI |
31-July-2025 |
| ACTINIUM PHARMACEUTICALS, INC. |
Iomab-ACT: A phase I/II study of 131-I apamistamab targeted lymphodepletion followed by CD19-targeted CAR T-cell therapy for patients with relapsed or refractory B-ALL or DLBCL |
DESAI, AVINASH |
NCI |
New York |
NY |
31-July-2025 |
| UNANDUP, LLC |
An Improved Robotic Electrophysiology Platform for Arrhythmia Ablation |
CREIGHTON, FRANCIS MILTON |
NHLBI |
SAINT LOUIS |
MO |
31-July-2025 |
| PROLOCOR INC. |
Validation of Platelet Expression of FcɣRIIa as a Precision Tool |
OHRNBERGER, JEANNE |
NHLBI |
SHELBURNE |
VT |
31-July-2025 |
| HELIXBIND, INC. |
Direct detection and identification of antimicrobial resistance genes in bloodstream infections |
SINGER, ALON |
NIAID |
Boxborough |
MA |
31-July-2025 |
| ALDATU BIOSCIENCES, INC. |
PANDAA for universal, pan-lineage molecular detection of filoviruses to enable rapid epidemic response. |
MACLEOD, IAIN JAMES |
NIAID |
Watertown |
MA |
31-July-2025 |
| HELIXBIND, INC. |
Direct from blood identification of bloodstream infections in newborns |
SINGER, ALON |
NIAID |
Boxborough |
MA |
31-July-2025 |
| ENZYME BY DESIGN, INC. |
Engineering in vivo half-life extension of a novel mammalian asparaginase to increase feasibility of pan-cancer therapy |
SCHALK, AMANDA M |
NCI |
CHICAGO |
IL |
31-July-2025 |
| INSOMA BIO, INC. |
Enhancing Peripheral Nerve Repair with an Injectable Recombinant Polypeptide Scaffold |
ROBERTS, STEFAN |
NINDS |
DURHAM |
NC |
31-July-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Inclusive Online Interactive Platform for Parents in Rural Settings to Promote Healthy Habits |
KNUTSON, MATTHEW |
NIMHD |
SAINT PAUL |
MN |
31-July-2025 |
| NEUROINDX INC. |
On-Chip Assay for Identifying Candidate Microtubule Binding Drugs to Treat ADRDs |
KARSTEN, STANISLAV |
NIA |
TORRANCE |
CA |
31-July-2025 |
| VIVREON BIOSCIENCES, LLC |
Development of a Novel Calcium Channel Therapeutic for Dystrophinopathies |
GREENBERG, MILTON L |
NIAMS |
San Diego |
CA |
31-July-2025 |
| BOLDEN THERAPEUTICS, INC. |
Preclinical characterization of splice-modifying antisense oligonucleotides targeting neurogenesis in human AD neural cells |
VALAT, ANNE |
NIA |
Providence |
RI |
31-July-2025 |
| PARTILLION BIOSCIENCE CORPORATION |
Hydrogel microparticle technology for high-throughout screening of chimeric antigen receptor-T cells based on single cell effector function |
DE RUTTE, JOSEPH |
NIGMS |
LOS ANGELES |
CA |
31-July-2025 |
| GLYCAN THERAPEUTICS CORPORATION |
Development of heparan sulfate-based therapeutics to treat inflammatory diseases |
WANG, ZHANGJIE |
NIGMS |
Raleigh |
NC |
31-July-2025 |
| MIDWEST BIOPROCESSING CENTER, LLC |
Production of Natural Deoxysugars for Use in Chemical Synthesis of Glycosides |
TURNER, ROBERT J. |
NIGMS |
Peoria |
IL |
31-July-2025 |
| BIOPAC SYSTEMS, INC. |
Temperature-Controlled Recording System for Wireless Data Acquisition from Immature Rodents |
ROWE, MANOEL |
NIMH |
GOLETA |
CA |
31-July-2025 |
| VENTRIX, INC. |
Pivotal Preclinical Studies of Novel Infusible ECM for Treating Acute MI |
KINSEY, ADAM M |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| OYAGEN, INC. |
High throughput screening and drug discovery for antagonists of the Ebola VP40 protein assembly |
SALTER, JASON DOUGLAS |
NIAID |
ROCHESTER |
NY |
31-July-2025 |
| PLANET BIOTECHNOLOGY, INC. |
Factor H Fc fusions as novel therapeutics for Burkholderia pseudomallei infections |
WYCOFF, KEITH |
NIAID |
HAYWARD |
CA |
31-July-2025 |
| KATHERA BIOSCIENCE INC. |
A Redesigning Existing Drugs against Indispensable Targets (ReEDIT) platform technology for discovery of novel drugs to treat fungal infections |
PARENT, STEPHEN |
NIAID |
UNION |
NJ |
31-July-2025 |
| TDA RESEARCH, INC. |
Filtration Media for In-Home PFAS Removal from Drinking Water |
DIETZ, STEVEN D |
NIEHS |
GOLDEN |
CO |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| JAVELIN BIOTECH |
Hepatic Clearance Chip for Pharmacokinetics |
CIRIT, MURAT |
NCATS |
Woburn |
MA |
31-July-2025 |
| SIGMOVIR BIOSYSTEMS, INC. |
Inducible HMGB1 antagonist for viral-induced acute lung injury. |
BLANCO, JORGE C |
NHLBI |
ROCKVILLE |
MD |
31-July-2025 |
| NANOHMICS, INC. |
Ambulatory cryocooling therapy device |
SAVOY, STEVE MICHAEL |
NIAMS |
AUSTIN |
TX |
31-July-2025 |
| YAYA SCIENTIFIC, LLC |
Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View |
BABA, JUSTIN |
NIBIB |
Nashville |
TN |
31-July-2025 |
| RADIATION DETECTION TECHNOLOGIES, INC. |
The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications. |
MONTAG, BENJAMIN |
NIBIB |
MANHATTAN |
KS |
31-July-2025 |
| FIBROTHERAPEUTICS, INC. |
Novel Therapeutic for Kidney Failure: A Modified, Water-Soluble Orally-Active Caveolin-1 Scaffolding Domain Peptide with Improved Characteristics for Drug Development |
HOFFMAN, STANLEY R |
NIDDK |
CHARLESTON |
SC |
31-July-2025 |
| ALLVIVO VASCULAR, INC. |
Catheter Cap with Anti-biofilm Luminal Insert |
NEFF, JENNIFER ANN |
NIDDK |
LAKE FOREST |
CA |
31-July-2025 |
| XFIBRA, INC. |
An Agnostic, Host-Direct Survival Cure MCM for Pulmonary Toxicants. |
BUCK, MARTINA |
NIAID |
Del Mar |
CA |
31-July-2025 |
| LITRON LABORATORIES, LTD. |
Development of a Comprehensive Hen's Egg Model for Genotoxicity Testing |
BRIGGS, ERICA |
NIEHS |
ROCHESTER |
NY |
31-July-2025 |
| NYTRICX INC. |
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| VITAN-BIOTECH, LLC |
Field-Deployable, low-Cost Point-of-Need urine test strips for mobile quantification of SUD medication drugs and their metabolites |
ZHOU, XICHUN |
NIDA |
Aurora |
CO |
31-July-2025 |
| CORTECHS LABS, INC. |
RSI-AI: Predicting clinically significant prostate cancer to guide biopsy decisions by combining advanced tissue microstructure imaging with deep learning |
WHITE, NATHAN SCOTT |
NCI |
San Diego |
CA |
31-July-2025 |
| VELLUM BIOSCIENCES LLC |
The development of a GMP eDHFR vector to monitor investigational CAR T cell therapies |
MILLER, DEREK |
NIAID |
PHILADELPHIA |
PA |
31-July-2025 |
| ZWICOAT MATERIALS INNOVATIONS, LLC |
Durable Zwitterionic Coatings: Dramatic Reduction of Implant-Induced Inflammation and Fibrosis |
HANSEN, KAMERON REX |
NIDCD |
SOLON |
IA |
31-July-2025 |
| BIOTHERAPEUTICS, INC. |
Development of Novel Therapeutics for Asthma |
BASSAGANYA-RIERA, JOSEP |
NHLBI |
BLACKSBURG |
VA |
31-July-2025 |
| ORLANCE, INC. |
Enhanced Seasonal Influenza Vaccine Targeting Variable and Conserved Antigens |
BAGLEY, KENNETH C |
NIAID |
SEATTLE |
WA |
31-July-2025 |
| AMYGDALA NEUROSCIENCES, INC. |
Investigational New Drug (IND)-enabling and Early-Stage Development of Selective, Reversible, Orally Bioavailable ALDH2 inhibitor ANS-00858 to Treat Alcohol Use Disorder. |
BLACKBURN, BRENT KEITH |
NIAAA |
PALO ALTO |
CA |
31-July-2025 |
| SIGMOVIR BIOSYSTEMS, INC. |
Inducible HMGB1 antagonist for viral-induced acute lung injury. |
BLANCO, JORGE C |
NHLBI |
ROCKVILLE |
MD |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| ACCURONIX THERAPEUTICS, INC. |
Preclinical Development of ACXT-3102 for the Treatment of Pancreatic Adenocarcinoma (PDAC) |
KELLER, BRADLEY T |
NCI |
St. Louis |
MO |
31-July-2025 |
| PXALPHA, LLC |
The re-activatable Yb-169 radiation source: a therapeutic medical device to reduce the risk of brachytherapy and increase adoption |
FLYNN, RYAN THOMAS |
NCI |
Iowa City |
IA |
31-July-2025 |
| SENSEION THERAPEUTICS, INC. |
Targeting SWELL1 Signaling to Treat Obesity-Induced Type 2 Diabetes |
LERNER, DANIEL J |
NIDDK |
SAINT LOUIS |
MO |
31-July-2025 |
| ACTINIUM PHARMACEUTICALS, INC. |
Iomab-ACT: A phase I/II study of 131-I apamistamab targeted lymphodepletion followed by CD19-targeted CAR T-cell therapy for patients with relapsed or refractory B-ALL or DLBCL |
DESAI, AVINASH |
NCI |
New York |
NY |
31-July-2025 |
| IMMUNOCHEM THERAPEUTICS, LLC |
Mitigation of Radiation Therapy Induced Neuroinflammation and Cognitive Dysfunction |
SHIFRIN, VICTOR |
NCI |
NEWTON |
MA |
31-July-2025 |
| MABDX, INC. |
Simultaneous Diagnosis of Dengue and Prognosis of Severe Dengue with a Single Point-of-Care Test |
MARUSICH, MICHAEL F |
NIAID |
EUGENE |
OR |
31-July-2025 |
| ARTIAM BIO INC. |
Treatment for cannabis use disorder |
SELTZMAN, HERBERT H |
NIDA |
CARY |
NC |
31-July-2025 |
| ARBORSENSE, INC. |
Rapid and non-invasive device for drug detection through sweat |
KULKARNI, GIRISH |
NIDA |
ANN ARBOR |
MI |
31-July-2025 |
| VIEWPOINT MOLECULAR TARGETING, INC. |
Image-guided dosimetry-based alpha particle therapy for neuroblastoma. |
SCHULTZ, MICHAEL KING |
NCI |
Coralville |
IA |
31-July-2025 |
| OMNISCIENT IMAGING, INC. |
Sedationless Multi-View High-Resolution Endoscopy |
BANERJEE, BHASKAR |
NCI |
Tucson |
AZ |
31-July-2025 |
| L2 DIAGNOSTICS, LLC |
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1 |
FIKRIG, EROL |
NIAID |
NEW HAVEN |
CT |
31-July-2025 |
| EPICYPHER, INC. |
Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cells |
KEOGH, MICHAEL-CHRISTOPHER |
NIAID |
Research Triangle Park |
NC |
31-July-2025 |
| PHYSICAL SCIENCES, INC |
Optical Redox Probe for Continuous Metabolic Monitoring during Natural Products Bioprocessing |
ZHAO, YOUBO |
NCCIH |
ANDOVER |
MA |
31-July-2025 |
| EXPERIAD, LLC |
Goalspace: A Platform for Parent-Assisted Behavioral Interventions |
JAKOBOVITS, REX M |
NIMH |
HONOLULU |
HI |
31-July-2025 |
| FOX CHASE CHEMICAL DIVERSITY CENTER, INC |
Development of Host- Oriented Therapeutics Targeting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), |
HARTY, RONALD N |
NIAID |
DOYLESTOWN |
PA |
31-July-2025 |
| EPIVAX, INC. |
Validation and Improvement of ISPRI-HCP: An Innovative Platform for Immunogenicity Risk Assessment of Process-related Protein Impurities |
HALTAUFDERHYDE, KIRK DONALD |
NIAID |
PROVIDENCE |
RI |
31-July-2025 |
| NXT BIOMEDICAL, LLC |
Interstitial pressure sensor to detect fluid status |
SCHWARTZ, ROBERT |
NHLBI |
IRVINE |
CA |
31-July-2025 |
| HABITAWARE, INC. |
Technology Assisted Treatment for Binge Eating Behavior |
KUMAR, SAMEER |
NIMH |
Minneapolis |
MN |
31-July-2025 |
| PARTILLION BIOSCIENCE CORPORATION |
Hydrogel microparticle technology for high-throughout screening of chimeric antigen receptor-T cells based on single cell effector function |
DE RUTTE, JOSEPH |
NIGMS |
LOS ANGELES |
CA |
31-July-2025 |
| DEEP BLUE MEDICAL ADVANCES, INC. |
A Biosynthetic Degradable Textile for Soft Tissue Reconstruction |
RUPPERT, DAVID |
NIGMS |
Durham |
NC |
31-July-2025 |
| REDBUD LABS, INC. |
Point-of-care HIV viral load system using RPA and MXR |
FISHER, JAY KENNETH |
NIMH |
Durham |
NC |
31-July-2025 |
| HELIXBIND, INC. |
Direct detection and identification of antimicrobial resistance genes in bloodstream infections |
SINGER, ALON |
NIAID |
Boxborough |
MA |
31-July-2025 |
| MABLOC, LLC |
Learning from the Ebola success: Can a mAb also save lives after yellow fever infection? |
WATKINS, DAVID I |
NIAID |
Washington |
DC |
31-July-2025 |
| MORGAN AND MENDEL GENOMICS, INC. |
Robust Predictor of Colon Cancer Risk |
OSTRER, HARRY |
NCI |
WILMINGTON |
DE |
31-July-2025 |
| NANOCELLECT BIOMEDICAL, INC. |
AI-Aided Tool for Day Zero Selection of High Performing Cells for Biopharma Cell Line Development |
CHO, SUNG HWAN |
NIGMS |
SAN DIEGO |
CA |
31-July-2025 |
| ALDATU BIOSCIENCES, INC. |
PANDAA for universal, pan-lineage molecular detection of filoviruses to enable rapid epidemic response. |
MACLEOD, IAIN JAMES |
NIAID |
Watertown |
MA |
31-July-2025 |
| AMBERGEN, INC |
New Technology for High-Resolution Antibody Profiling for SARS-CoV-2 |
LIM, MARK |
NIAID |
WATERTOWN |
MA |
31-July-2025 |
| KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT |
Home-Based Parent-Child Intervention to Enhance Executive Function |
ANDERSON, SHANE M. |
NIMH |
Minneapolis |
MN |
31-July-2025 |
| HELIXBIND, INC. |
Direct from blood identification of bloodstream infections in newborns |
SINGER, ALON |
NIAID |
Boxborough |
MA |
31-July-2025 |
| BRIDGESOURCE MEDICAL CORPORATION |
Technology-Enabled Financial Planning for Caregivers and Clients with Reduced Capacity |
PORTERFIELD, JOHN E |
NIA |
AUSTIN |
TX |
31-July-2025 |
| NEUROTARGETING SYSTEMS |
A novel system and procedure for non-surgical placement of EEG electrodes in mice |
GERASHCHENKO, LUDMILA |
NIMH |
BROOKLINE |
MA |
31-July-2025 |
| HENLEY ION, LLC |
A micronized electrostatic precipitator for next-generation respiratory protection against pathogenic aerosols |
HENLEY, JULIAN |
NIAID |
Mandeville |
LA |
31-July-2025 |
| SOMATOLYNK, INC. |
SMALL MOLECULE THERAPEUTIC FOR ALZHEIMER'S DISEASE |
WITT, KEN |
NIA |
EDWARDSVILLE |
IL |
31-July-2025 |
| BLOOMER HEALTH TECH INC |
Bloomer Augmented Garment Platform-Barrier Removal for women in cArdiac rehab (BRA) |
CHONG, ALICIA |
NHLBI |
CAMBRIDGE |
MA |
31-July-2025 |
| AVANTI BIOSCIENCES, INC. |
USE OF DYRK1A/B KINASE INHIBITORS FOR THE TREATMENT OF LIVER DISEASES |
ARALDI, GIAN LUCA |
NIDDK |
EAST SETAUKET |
NY |
31-July-2025 |
| NEURONOFF, INC. |
The Injectrode- An injectable, easily removable electrode as a trial lead for baroreceptor activation therapy to treat hypertension and heart failure |
FRANKE, MANFRED |
NHLBI |
VALENCIA |
CA |
31-July-2025 |
| KAIROS RESEARCH LLC |
MiDiario: Mobile Intervention for Diabetes via Reflection and Introspection in My Own Words |
SUMMERVILLE, AMY |
NIMHD |
DAYTON |
OH |
31-July-2025 |
| VENTRIX, INC. |
Pivotal Preclinical Studies of Novel Infusible ECM for Treating Acute MI |
KINSEY, ADAM M |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| ACURASTEM, INC. |
Development of an UNC13A antisense oligonucleotide treatment for ALS and FTD |
SAZANI, PETER |
NINDS |
Monrovia |
CA |
31-July-2025 |
| OREGON RES BEHAVIORAL INTERVENTION STRAT |
HealthyU-Latinx: A Technology-based Tool for addressing Health Literacy in Latinx Secondary Students and their Families |
SMITH, DAVID RANDOLPH |
NIMHD |
Springfield |
OR |
31-July-2025 |
| SEE YOURSELF HEALTH, LLC |
The HOPE App: An Immersive Telehealth Solution for Older Adults with Diabetes |
DRASCHER, MAXWELL LEE |
NIA |
BEVERLY |
MA |
31-July-2025 |
| WR BIOTECH, LLC |
Protection of donor kidneys with synchronization modulation electric field (SMEF) |
LIU, RUISHENG |
NIDDK |
TAMPA |
FL |
31-July-2025 |
| BRIDGESOURCE MEDICAL CORPORATION |
Post Cardiac Surgery Hemodynamics Diagnostic Device |
KOTTAM, ANIL |
NIBIB |
AUSTIN |
TX |
31-July-2025 |
| LITTLE ROOM INNOVATIONS, LLC |
Biomechanical Evaluation of a Novel, Compliant Low Profile Prosthetic Foot |
BARTLETT, HARRISON LOGAN |
NICHD |
ANN ARBOR |
MI |
31-July-2025 |
| JBS SCIENCE, INC. |
Development of a Urine Genetic Test for NonMuscle Invasive Bladder Cancer |
LIN, SELENA |
NHGRI |
DOYLESTOWN |
PA |
31-July-2025 |
| ELECTRONIC BIOSCIENCES, INC. |
Point-of-Care Multiplexed Immunosuppressant Monitoring |
SCHIBEL, ANNA |
NIAID |
SAN DIEGO |
CA |
31-July-2025 |
| MICROBIOTIX, INC |
Development of antibody drug conjugates as pan-filo antivirals |
LIU, GAI |
NIAID |
WORCESTER |
MA |
31-July-2025 |
| MOLECULAR THERANOSTICS, LLC |
Development of peptide drug conjugates for cancer therapy |
HALL, RYAN CHRISTOPHER |
NCI |
BEACHWOOD |
OH |
31-July-2025 |
| JAVELIN BIOTECH |
Hepatic Clearance Chip for Pharmacokinetics |
CIRIT, MURAT |
NCATS |
Woburn |
MA |
31-July-2025 |
| LAMPROGEN, INC. |
An expanded 75-color panel of Pdots for spectral multiplexing |
YU, JIANGBO |
NIGMS |
SEATTLE |
WA |
31-July-2025 |
| AMYGDALA NEUROSCIENCES, INC. |
Investigational New Drug (IND)-enabling and Early-Stage Development of Selective, Reversible, Orally Bioavailable ALDH2 inhibitor ANS-00858 to Treat Alcohol Use Disorder. |
BLACKBURN, BRENT KEITH |
NIAAA |
PALO ALTO |
CA |
31-July-2025 |
| TRETHERA CORPORATION |
Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Acute Disseminated Encephalomyelitis (ADEM) |
SCHULTZ, KENNETH |
NIAID |
SHERMAN OAKS |
CA |
31-July-2025 |
| BIOMEDICAL DEVELOPMENT CORPORATION |
Real World Adoption of an OUD Digital Health Therapeutic |
SIEGEL, GREGG |
NIDA |
Lexington |
KY |
31-July-2025 |
| CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC |
STARTUP Central |
FRIIS, ELIZABETH A |
NIGMS |
LAWRENCE |
KS |
31-July-2025 |
| ECLIPSE ORTHOPAEDICS, LLC |
Fluoroscopic drill attachment for orthopedic trauma surgery |
RICH, DAVID BOYD |
NIAMS |
WARSAW |
IN |
31-July-2025 |
| PROTON BIO, INC. |
Targeting proton-sensing GPR68 as a ferroptosis-based therapy for glioblastoma |
WILLIAMS, CHARLES HOUSTON |
NCI |
BALTIMORE |
MD |
31-July-2025 |
| ABBRATECH, INC. |
Method for the validation by Western analysis of affinity reagents against post-translationally modified proteins. |
WEINER, MICHAEL P |
NIGMS |
Branford |
CT |
31-July-2025 |
| GLYCAN THERAPEUTICS CORPORATION |
Development of heparan sulfate-based therapeutics to treat inflammatory diseases |
WANG, ZHANGJIE |
NIGMS |
Raleigh |
NC |
31-July-2025 |
| RITHIM BIOLOGICS, INC. |
Novel Gene Therapy, Techniques, and Devices to Prevent Ventricular Tachycardia |
ANDERSON, RONALD LEE |
NHLBI |
WOODBINE |
MD |
31-July-2025 |
| AMYGDALA NEUROSCIENCES, INC. |
Investigational New Drug (IND)-enabling and Early-Stage Development of Selective, Reversible, Orally Bioavailable ALDH2 inhibitor ANS-00858 to Treat Alcohol Use Disorder. |
BLACKBURN, BRENT KEITH |
NIAAA |
PALO ALTO |
CA |
31-July-2025 |
| CYTEX THERAPEUTICS INC. |
Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model |
ESTES, BRADLEY T |
NIAMS |
DURHAM |
NC |
31-July-2025 |
| COVE TECHNOLOGY CONSULTING LLC |
A closed-loop gravity infusion control device |
KAWAHARA, CHIE |
NINR |
BAINBRIDGE ISLAND |
WA |
31-July-2025 |
| LAMASSU BIO INC |
Development of a novel small molecule MDM2 inhibitor for innovative sarcoma treatment |
HANNA, GABI |
NCI |
DURHAM |
NC |
31-July-2025 |
| BD HOLDING, INC. |
An Improved Epigenetic Algorithm for Guiding Low Dose CT Lung Cancer Screening |
PHILIBERT, ROBERT A |
NCI |
IOWA CITY |
IA |
31-July-2025 |
| REELIN THERAPEUTICS, INC. |
Effect of APP copy number variants in Alzheimer's disease and and Down Syndrome on Reelin expression and function |
KOUNNAS, MARIA Z |
NIA |
SAN DIEGO |
CA |
31-July-2025 |
| PEACEFULLY, INC. |
A comprehensive web-based program to help advanced cancer patients plan for end of life |
GOOD, JENNIFER |
NINR |
WOODLAND HILLS |
CA |
31-July-2025 |
| MILLION MARKER WELLNESS INC. |
A Personalized Digital Intervention Program to Reduce Exposure to Endocrine Disrupting Chemicals among a Child-Bearing Age Cohort |
HUA, JENNA |
NIEHS |
EL CERRITO |
CA |
31-July-2025 |
| SIRPANT IMMUNOTHERAPEUTICS, INC. |
SIRPant Technology for anti-Cancer Immunity |
MCCURLEY, NATHANAEL |
NCI |
CHAMBERSBURG |
PA |
31-July-2025 |
| MICROBRIGHTFIELD, LLC |
NeuroExM |
GLASER, JACOB R |
NIMH |
WILLISTON |
VT |
31-July-2025 |
| BARRON ASSOCIATES, INC. |
Respiratory Oxygen Adherence Monitor for COPD Patients |
KREPKOVICH, EILEEN T. |
NHLBI |
CHARLOTTESVILLE |
VA |
31-July-2025 |
| PETCOIL, INC. |
A Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging |
CHANG, CHENMING |
NIMH |
Sunnyvale |
CA |
31-July-2025 |
| BLOOMER HEALTH TECH INC |
Bloomer Augmented Garment Platform-Barrier Removal for women in cArdiac rehab (BRA) |
CHONG, ALICIA |
NHLBI |
CAMBRIDGE |
MA |
31-July-2025 |
| SENTRIMED, INC. |
Targeting OSCC cells with a lozenge to treat oral cancer |
GOLDBERG, GARY |
NCI |
MULLICA HILL |
NJ |
31-July-2025 |
| KOMMODO THERAPEUTICS LLC |
Engineered gamma delta T cells for systemic correction of dystrophic epidermolysis bullosa |
SHIRKEY-SON, NICOLE J. |
NIAMS |
SHIREVIEW |
MN |
31-July-2025 |
| PALMETTO INNOVATIVE EDUCATION, LLC |
SimuVersity Medical Center: Pain and opioid management training in diverse patient populations |
BORCKARDT, JEFFREY J |
NIDA |
MOUNT PLEASANT |
SC |
31-July-2025 |
| MOREMME VA LLC |
Hormone-Free Prebiotic Muco-Adhesive Gels To Treat Vaginal Atrophy in Post-Menopausal Women |
AKANDE-DOKUN, JANET |
NIA |
JOHNS CREEK |
GA |
31-July-2025 |
| INPRINT BIO LLC |
MuscleInk: A multifunctional colloidal scaffold for the treatment of muscle loss |
MEMIC, ADNAN |
NIAMS |
FARMINGTON |
CT |
31-July-2025 |
| AMPEDRNA BIOSCIENCES LLC |
Highly stable mini-circRNA vaccine with maximally activated and long-lasting T cells for HPV-related cancer combination immunotherapy |
PARRY, GORDON |
NCI |
RICHMOND |
VA |
31-July-2025 |
| DASISIMULATIONS LLC |
Rapid, Automatic, AI Driven, Aortic Valve Measurement Software |
DASI, LAKSHMI PRASAD |
NHLBI |
DUBLIN |
OH |
31-July-2025 |
| PRECISION QUANTOMICS INC |
Addressing health disparities through a quantitative physiological database and precision systems modeling |
WATSON, CHRISTY J.W. |
NIMHD |
SPOKANE |
WA |
31-July-2025 |
| BIOXYTECH RETINA, INC. |
Addressing Health Disparities through AI-Enhanced Prediction of Diabetic Retinopathy |
BASIRI, ALI |
NIMHD |
Richmond |
CA |
31-July-2025 |
| UNANDUP, LLC |
An Improved Robotic Electrophysiology Platform for Arrhythmia Ablation |
CREIGHTON, FRANCIS MILTON |
NHLBI |
SAINT LOUIS |
MO |
31-July-2025 |
| LEAFLABS, LLC |
Untethered high channel count electrophysiology for freely-moving animals |
SHERWOOD, JOHN L |
NIMH |
CAMBRIDGE |
MA |
31-July-2025 |
| LUCERNA, INC. |
Targeted RNA degradation assay for new antiviral drug discovery |
O'HANLON, RYAN |
NIAID |
Brooklyn |
NY |
31-July-2025 |
| UBITRIX INTERNATIONAL, INC. |
mVOR: An mHealth Approach to the Clinical Assessment of Gaze Stability and Telerehabilitation of Vestibular Dysfunction |
AHAMED, SHEIKH IQBAL |
NIDCD |
MILWAUKEE |
WI |
31-July-2025 |
| SPACERX LLC |
Revolutionizing Nicotine Vaping and Electronic Nicotine Delivery Systems Addiction Treatment through Innovative E-Vape Administration of Cytisine to Enhance Patient Adherence and Treatment Completion. |
LEE, PETER H |
NIDA |
RESTON |
VA |
31-July-2025 |
| NYTRICX INC. |
Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| MAGNETIC TIDES, INC. |
Exploring the Parameter Space of High Frequency Magnetic Perturbation in Manipulating Neural Excitability and Plasticity. |
LABRUNA, LUDOVICA |
NINDS |
EL CERRITO |
CA |
31-July-2025 |
| MILLION MARKER WELLNESS INC. |
A Personalized Digital Intervention Program to Reduce Exposure to Endocrine Disrupting Chemicals among a Child-Bearing Age Cohort |
HUA, JENNA |
NIEHS |
EL CERRITO |
CA |
31-July-2025 |
| VALA SCIENCES, INC. |
Combined Cardiomyopathy, e.g., of Cancer Chemotherapeutics, and Proarrhythmia for Cardiotoxicity Clinical Trials-in-a-Dish (CTiD) with iPSC-Derived Cardiomyocytes |
PRICE, JEFFREY H. |
NHLBI |
SAN DIEGO |
CA |
31-July-2025 |
| IMMUNOSHIELD THERAPEUTICS INC. |
Islet dosing and loading density in injection molded macroencapsulation devices |
SNIR, OREN |
NIDDK |
CHANDLER |
AZ |
03-August-2025 |
| APCBIO INNOVATIONS, INC. |
Recombinant human CC10 protein for treatment and prevention of chronic lung allograft dysfunction |
PILON, APRILE L |
NHLBI |
Frederick |
MD |
04-August-2025 |
| BIOPLATINUM TECHNOLOGIES, LLC |
Precision medicine for pancreatic cancer. Biomarker-guided drug delivery of platinum to tumors |
FARRELL, NICHOLAS PATRICK |
NCI |
RICHMOND |
VA |
05-August-2025 |
| BRANCHPOINT BIOSCIENCES INC. |
A Comprehensive qPCR-Based Oral Microbiome Profiling Platform for Research and Discovery |
TULLY, BENJAMIN |
NIDCR |
PASADENA |
CA |
06-August-2025 |
| BLOTTING INNOVATIONS, LLC |
Gelbrane: Combined Gel and Membrane for Robust Western Blotting |
BIRTWISTLE, MARC R. |
NIGMS |
CENTRAL |
SC |
07-August-2025 |
| RAM MEDICAL INNOVATIONS, INC. |
New Arterial Sheath for Stroke and Other Neurovascular Interventions. |
SYED, MUBIN |
NHLBI |
SPRINGFIELD |
OH |
14-August-2025 |
| CONSEGNA PHARMA, INC. |
Long-acting injectable ketamine for improved substance use disorder (SUD) treatment without dissociative effects. |
ZANA, LAWRENCE J |
NIDA |
PITTSBURGH |
PA |
14-August-2025 |
| TRIANGLE BIOTECHNOLOGY, INC. |
Development of nanodroplet enhanced ultrasonic cavitation technologyto enable the study of chromatin accessibility in FFPE tissues |
ALLISON, DAVID F |
NIGMS |
Chapel Hill |
NC |
14-August-2025 |
| SEEUS95 INC |
Reusable, transparent, and reconfigurable N95-equivalent Respirator Masks: design, fabrication, and trials for enhanced adoption |
CHUN, ALICE |
NIDCD |
NEW YORK |
NY |
14-August-2025 |
| ADVANCED MEDICAL ELECTRONICS CORPORATION |
Innovative Pneumothorax Decompression Device |
STRUTT, JONATHAN R |
NHLBI |
MAPLE GROVE |
MN |
14-August-2025 |
| CLINIC CHAT LLC |
Substance Use Disorder Artificially Intelligent chatbot for screening, assessment & referral: SUD Bot |
BULL, SHEANA S |
NIDA |
DENVER |
CO |
14-August-2025 |
| PANORAMA RESEARCH, INC. |
Novel therapy to prevent alveolar bone loss in severe periodontitis |
LARRICK, JAMES W |
NIDCR |
SUNNYVALE |
CA |
14-August-2025 |
| BRAINXELL, INC. |
Accelerating Functional Maturation of Human iPSC-Derived Astrocytes |
KONG, LINGHAI |
NIMH |
Madison |
WI |
16-August-2025 |
| CALLENTIS CONSULTING GROUP LLC |
High-performance BPA-free dental restoration composites with remineralization capabilities |
STANSBURY, JEFFREY W. |
NIDCR |
AUSTIN |
TX |
18-August-2025 |
| RESHAPE LIFESCIENCES, INC. |
Diabetic Targeted Dual Neuromodulation Parametric Optimization |
WAATAJA, JON JAMES |
NIDDK |
Irvine |
CA |
19-August-2025 |
| LAUREN SCIENCES, LLC |
LAUR-201 (V-Smart®-TNV for Neuro-HIV): Novel V-Smart® Nanomedicine for Treatment of HAND |
ROSENBAUM, SUSAN K |
NIMH |
NEW YORK |
NY |
19-August-2025 |
| PHASE GENOMICS, INC. |
Chromosomal aberration detection in FFPE tissue using proximity ligation sequencing |
EACKER, STEPHEN MATTHEW |
NCI |
SEATTLE |
WA |
30-August-2025 |
| NEUROMUSCULAR DYNAMICS, LLC |
A simple and quantitative clinical assessment of neuromuscular recovery after ACL injury |
VALERO, ERIKA |
NIAMS |
La Crescenta |
CA |
30-August-2025 |
| PHASE GENOMICS, INC. |
Chromosomal aberration detection in FFPE tissue using proximity ligation sequencing |
EACKER, STEPHEN MATTHEW |
NCI |
SEATTLE |
WA |
30-August-2025 |
| MINUTIA, INC. |
Monitoring graft responses to the transplant niche in allogeneic cell replacement therapy |
DIGOVICH, CATHERINE |
NIDDK |
OAKLAND |
CA |
30-August-2025 |
| MINUTIA, INC. |
Monitoring graft responses to the transplant niche in allogeneic cell replacement therapy |
DIGOVICH, CATHERINE |
NIDDK |
OAKLAND |
CA |
30-August-2025 |
| BIOSENSING INSTRUMENT, INC. |
Plasmonic Scattering Microscopy for high-throughput in-situ quantification of molecular binding kinetics on single cells |
LY, NGUYEN |
NIGMS |
TEMPE |
AZ |
30-August-2025 |
| ARMIDA LABS, INC. |
Targeting pancreatic cancer metastases with Targefrin |
BAGGIO, CARLO |
NCI |
SAN DIEGO |
CA |
30-August-2025 |
| AUTOIVF, INC. |
OvaSafe: A microfluidic device enabling automated oocyte vitrification |
OZKUMUR, ISMAIL EMRE |
NICHD |
Natick |
MA |
31-August-2025 |
| BDH PHARMA, LLC |
Development of cannabinoid-opioid combination with opioid sparing and synergistic analgesic effects to prevent opioid use disorder and overdose. |
BRIONES, MARISA |
NIDA |
Studio City |
CA |
31-August-2025 |
| CAYMAN CHEMICAL COMPANY, INC. |
Novel Small Molecule for Improved Dental Implant Osseointegration |
MORANO, MARIA INES |
NIDCR |
ANN ARBOR |
MI |
31-August-2025 |
| OSTEOCENTRIC TECHNOLOGIES, INC. |
Optimization of a Novel Thread Geometry for Various Orthopedic Surgery Applications |
FAUTH, ANDREW RAY |
NIAMS |
Austin |
TX |
31-August-2025 |
| THERMAQUIL, INC. |
Drug Free Nerve Block Device for the Relief of Pain and Symptoms in Migraines and other Headaches |
POPIELARSKI, STEPHEN |
NINDS |
PHILADELPHIA |
PA |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Chair to Prevent and Treat Pressure Injuries in Persons Living with Alzheimer's Disease and Related Dementias |
SEIFERT, SARA |
NIA |
SAINT PAUL |
MN |
31-August-2025 |
| COURAGENE, INC. |
Engineering Chemically Modified RNPs for Effective Treatment of Angelman Syndrome |
XIE, YING |
NINDS |
EDISON |
NJ |
31-August-2025 |
| ONCURIE INC. |
A novel platform for targeted radiopharmaceuticals for imaging and therapy of ovarian cancer |
LAPI, SUZANNE ELIZABETH |
NCI |
RALEIGH |
NC |
31-August-2025 |
| ADDINEX TECHNOLOGIES, INC. |
Integration of an opioid dispensing, monitoring, and disposal platform with a hospital pharmacy to reduce opioid use by discharged emergency department patients |
ROSLYAKOV, STANISLAV |
NIDA |
NEW YORK |
NY |
31-August-2025 |
| FINNEGAN THE DRAGON, INC |
Development of preschool speech-to-print curricula with online gaming technology for early language development |
CADIZ, EMILY JOHN |
NICHD |
HILLSBORO |
OR |
31-August-2025 |
| GYNION, LLC |
Development of ablative therapy for the destruction of cervical neoplasia |
SHIKHMAN, OLEG |
NCI |
TRUMBULL |
CT |
31-August-2025 |
| TEO THERAPEUTICS INCORPORATED |
Reimagining Pharmaceutical Drug Development in Oncology with a Biomimetic Platform |
KELLER, CHARLES |
OD |
BEAVERTON |
OR |
31-August-2025 |
| LASE INNOVATION INC. |
Time-lapse Flow Cytometry for Kinetic Profiling of T-Cell Function |
KWOK, SHELDON J.J. |
NCI |
Waltham |
MA |
31-August-2025 |
| NEURONASAL INC |
Circumventing the pharmacokinetic/pharmacodynamic limitations of antioxidant therapy for Parkinson's Disease by nose to brain delivery of N-acetylcysteine |
GREENE, DOUGLAS |
NIA |
WEXFORD |
PA |
31-August-2025 |
| RESILIENT LIFESCIENCE, INC. |
Developing a wearable medical device to detect opioid overdose |
HOLDEN, BRADFORD A |
NIDA |
Pittsburgh |
PA |
31-August-2025 |
| AQUALUNG THERAPEUTICS CORP. |
A Randomized Phase 2A Clinical Trial Pioneering the Utility of an eNAMPT-Reducing Therapy in ARDS/VILI: the PUERTA Trial |
GARCIA, JOE G. N. |
NHLBI |
Juno Beach |
FL |
31-August-2025 |
| MODULATION THERAPEUTICS, INC. |
Modulation of cancer induced immune suppression via inhibition of SCD1 |
HAYES, KAREN E |
NCI |
MORGANTOWN |
WV |
31-August-2025 |
| HELIXOMER, INC. |
Development of an RNA-based anticoagulant and antidote for precise on/off coagulation control during cardiovascular procedures |
KRISSANAPRASIT, ABHICHART |
NHLBI |
HILLSBOROUGH |
NC |
31-August-2025 |
| SYLVATICA BIOTECH, INC. |
Extended preservation of human livers: a nature inspired, high subzero controlled, limited freezing approach |
BAICU, SIMONA C |
NIDDK |
NORTH CHARLESTON |
SC |
31-August-2025 |
| QUELL TX, INC. |
BRITE-Eye: An integrated discovery engine for CNS therapeutic targets driven by high throughput genetic screens, functional readouts in human neurons, and machine learning |
WILLIAMS, LUIS ALBERTO |
NIMH |
CAMBRIDGE |
MA |
31-August-2025 |
| HUMAN CELL CO |
Topical treatment of an optimized NGF for Dry Eye |
JEONG, SOON SEOG |
NEI |
NAPERVILLE |
IL |
31-August-2025 |
| AMYDIS DIAGNOSTICS, INC. |
Use of novel fluorescent tracers to develop a comprehensive retinal biomarker database that maps the heterogeneity of Alzheimer's pathogenesis |
SARRAF, STELLA |
NIA |
La Jolla |
CA |
31-August-2025 |
| CALLA HEALTH FOUNDATION |
Optimizing ablation of cervical precancer with ethyl cellulose ethanol to enable translation to women in low and middle-income countries |
CROUCH, BRIAN |
NCI |
DURHAM |
NC |
31-August-2025 |
| SPINEX, INC. |
Spinal Cord Innovation in Pediatrics to Treat Cerebral Palsy (SCiP Clinical Study) |
GAD, PARAG |
NICHD |
NORTHRIDGE |
CA |
31-August-2025 |
| EPICYPHER, INC. |
Multiomic genomic mapping with long read sequencing |
BURG, JONATHAN MICHAEL |
NIGMS |
Research Triangle Park |
NC |
31-August-2025 |
| FORTISCIENCE, INC. |
Development of a Small Molecule Inhibitor of Fortilin for Atherosclerosis Treatment and Prevention |
FUJISE, KEN |
NHLBI |
Dover |
DE |
31-August-2025 |
| DIRECTSEQ BIOSCIENCES, INC. |
High-throughput Direct Sequencing and Quantitative Mapping of RNA Modifications using Mass Spectrometry. |
ZHANG, SHENGLONG |
NHGRI |
WOODCLIFF LAKE |
NJ |
31-August-2025 |
| NOVOMEDIX, INC. |
Definitive (GLP) Toxicity and Toxicology Studies for a Novel Small Molecule for Protection Against Cardiotoxicity in Triple Negative Breast Cancer |
SWINDLEHURST, CATHY A |
NHLBI |
SAN DIEGO |
CA |
31-August-2025 |
| IMMUNOPHOTONICS, INC. |
Development of polymeric synthetic biomaterial IP-001 to potentiate asystemic immunotherapy of hepatocellular carcinoma via thermal ablation |
LAM, SIU KIT |
NCI |
St. Louis |
MO |
31-August-2025 |
| LYNNTECH, INC. |
Cutaneous Gel Delivering an Intriguing MOA Therapeutic to Treat DFU |
SHARMA, ANJAL C |
NIDDK |
COLLEGE STATION |
TX |
31-August-2025 |
| VIVACELLE BIO, INC. |
Development of VBI-1 as a novel treatment protocol for outpatient cardiac arrest |
SIMPKINS, CUTHBERT ORMOND |
NHLBI |
Fort Wayne |
IN |
31-August-2025 |
| B A MAZE, INC. |
Connection, Independence, and Circular Support: Prompted Health Awareness Enabled by the At-Home Health Station |
MAZUR, ROBERT |
NIA |
Louisville |
KY |
31-August-2025 |
| PHARYNVAC SURGICAL TECHNOLOGY INC. |
Development of a novel kit for reduction of aerosolized particles during endonasal surgeries: the PharynVac Device |
ILORETA, ALFRED-MARC |
NIBIB |
BROOKLYN |
NY |
31-August-2025 |
| ILLUMINANT SURGICAL, INC. |
Software Development and Cadaveric Testing of Deformable Registration Pipeline in Novel Camera-Projector Surgical Navigation Device |
HU, JAMES |
NIA |
PALO ALTO |
CA |
31-August-2025 |
| TAKEOFF41, INC. |
An AI-driven total parenteral nutrition platform for cost-effective and scientifically personalized nutrition for premature newborns |
PHONGPREECHA, THANAPHONG |
NICHD |
PORTOLA VALLEY |
CA |
31-August-2025 |
| 3D BIOANALYTIX, INC. |
Development of a blood-based test for neurodegenerative diseases |
PANKOW, SANDRA |
NIA |
SAN DIEGO |
CA |
31-August-2025 |
| 231 SHEEP LLC |
Ocuelar: Revolutionizing Glaucoma Management in Medically Underserved Communities |
LEE, SCOTT |
NIA |
SAN GABRIEL |
CA |
31-August-2025 |
| ALUME BIOSCIENCES, INC. |
Development of ALM-488 for nerve and ureter visualization during abdominal surgery |
WHITNEY, MICHAEL A |
NCI |
San Diego |
CA |
31-August-2025 |
| SPECTREE INC. |
Multispectral Sensor for Chemical Composition Analysis of Ultrafine Aerosols in Air Quality Assessment |
MAMISHEV, ALEXANDER V |
NIEHS |
SEATTLE |
WA |
31-August-2025 |
| CANCER TARGETED TECHNOLOGY, LLC |
Development of an Innovative PSMA-Targeted Small Molecule Prodrug for Prostate Cancer |
LANGTON-WEBSTER, BEATRICE |
NCI |
WOODINVILLE |
WA |
31-August-2025 |
| COG ANALYTICS, LLC |
Mindfulness Based Stress Reduction App for African American Caregivers |
CARSWELL, STEVEN BERNARD |
NIA |
POTOMAC |
MD |
31-August-2025 |
| PRAEVENTIX, LLC |
IND Enabling Studies for the Development of Pruritus Therapeutic PRA-523 |
PIPPIN, DOUGLAS ANTHONY |
NIAMS |
EXTON |
PA |
31-August-2025 |
| BIOAESTHETICS CORPORATION |
PHMB-Impregnated Acellular Biologic Grafts for Treatment of Third-Degree Burns |
BLUM, JULIANA LYN |
NIGMS |
DURHAM |
NC |
31-August-2025 |
| EINSENCA INC. |
PET Imaging of Damaging Neuroinflammation in Alzheimer's Disease |
LARSON, ANDREW CHRISTIAN |
NIA |
DOVER |
DE |
31-August-2025 |
| ATOMO, INC |
Finding undiagnosed ATTR-CM patients using AI technology in clinical settings |
MYERS, KELLY D |
NHLBI |
WEST LAKE HILLS |
TX |
31-August-2025 |
| SYNAPTIC HEALTH LLC |
A novel closed-loop feedback neuromodulation system for improving slow wave sleep in Alzheimer's disease patients |
KROHN, BRIAN |
NIA |
NEW BRIGHTON |
MN |
31-August-2025 |
| CONIFER POINT PHARMACEUTICALS, LLC |
A Web Service for Fragment-based Selectivity Analysis of Drug Leads |
KULP III, JOHN LAURENCE |
NIGMS |
DOYLESTOWN |
PA |
31-August-2025 |
| MERIDIAN BIOTECH, LLC |
Development and Production of Standardized Reference Diets for Zebrafish Research |
CORACE, DONALD |
OD |
WOODLANDS |
TX |
31-August-2025 |
| RADIATION MONITORING DEVICES, INC. |
Semiconductor detector for low-dose, high-resolution dental DR imaging |
CHRISTIAN, JAMES F |
NIDCR |
WATERTOWN |
MA |
31-August-2025 |
| THINK THERAPEUTICS, INC. |
Machine learning optimized autoimmune therapeutics with a focus on Type 1 Diabetes |
GIFFORD, DAVID K |
NIAID |
NEWTON |
MA |
31-August-2025 |
| TREVARX BIOMEDICAL, INC. |
Optimizing Radiosynthetic Yield of [18F]FTT For Wide-Spread Distribution |
MIKHAIL, MICHEL |
NCI |
PHILADELPHIA |
PA |
31-August-2025 |
| LINSHOM MEDICAL INC |
Advanced Prediction of Emerging Respiratory Decline with the Linshom Continuous Predictive Respiratory Sensor (CPRS) |
FELDMAN, RONEN |
NHLBI |
ELLICOTT CITY |
MD |
31-August-2025 |
| UP THERAPEUTICS, INC. |
Development of a novel small molecule RPN13 inhibitor and therapeutic for advanced ovarian cancer patients |
ANCHOORI, RAVI KUMAR |
NCI |
Frederick |
MD |
31-August-2025 |
| SAROS THERAPEUTICS INC |
Process Development and Preclinical Advancement of a Novel Nanoparticle Formulation for Immune Activation |
JOHNSON, RICHARD |
NCI |
CHICAGO |
IL |
31-August-2025 |
| SUS CLINICALS, INC. |
Validation of the Genetically Malleable Oncopig Hepatocellular carcinoma (HCC) Model for Targeted Therapeutic Development |
SCHACHTSCHNEIDER, KYLE |
NCI |
CINCINNATI |
OH |
31-August-2025 |
| ANELLEO, INC. |
Mucoadhesive film for the treatment of vestibulodynia |
JANUSZIEWICZ, RIMA |
NICHD |
CHAPEL HILL |
NC |
31-August-2025 |
| AIQ SOLUTIONS, INC. |
Comprehensive Assessment of Cancer Theranostics Response |
PERK, TIMOTHY |
NCI |
MADISON |
WI |
31-August-2025 |
| PERCEPTIVE TECHNOLOGIES, INC. |
Developing an Optical Coherence Tomography (OCT) based handheld intraoral scanner for dentistry |
KANG, WEI |
NIDCR |
BOSTON |
MA |
31-August-2025 |
| KLEIN BUENDEL, INC. |
Hybrid Delivery to Increase Access and Sustainability: Evaluating ezParent Implementation |
BREITENSTEIN, SUSAN M |
NICHD |
GOLDEN |
CO |
31-August-2025 |
| JILLION THERAPEUTICS INC. |
The use of DNA-encoded library (DEL) technology for the identification of therapeutic molecules to treat opioid use disorders (OUDs) |
FLAJOLET, MARC |
NIDA |
NEW YORK |
NY |
31-August-2025 |
| ADAPTIVE TESTING TECHNOLOGIES |
Modifying and validating the K-CAT mental health scales for children and adolescents on the autism spectrum |
COHEN, YEHUDA |
NIMH |
CHICAGO |
IL |
31-August-2025 |
| NYTRICX INC. |
Enhanced Prosthetic Vascular Graft Function by Local Release of Nitric Oxide |
SHEBUSKI, RONALD J. |
NHLBI |
ATHENS |
GA |
31-August-2025 |
| OLMEDA BIOSCIENCES LLC |
Development of a Novel Aqueous Humor-Based Multiplex Assay for Uveal Melanoma Metastatic Risk Prediction |
XU, LIYA |
NCI |
SAN DIEGO |
CA |
31-August-2025 |
| ENDOMIMETICS, LLC |
Atherosclerosis assay development for drug efficacy and cytotoxicity screening |
CHEN, JUN |
NHLBI |
BIRMINGHAM |
AL |
31-August-2025 |
| LINSHOM MEDICAL INC |
Advanced Prediction of Emerging Respiratory Decline with the Linshom Continuous Predictive Respiratory Sensor (CPRS) |
FELDMAN, RONEN |
NHLBI |
ELLICOTT CITY |
MD |
31-August-2025 |
| SOCIALRX INC |
Personalized arts prescriptions for behavioral health challenges in the US |
BAILEY, LUCY |
NCCIH |
ATLANTA |
GA |
31-August-2025 |
| VENOVA TECHNOLOGIES, INC. |
A novel, non-hormonal, long-acting female contraceptive device |
MAN, EMILY |
NICHD |
CAMBRIDGE |
MA |
31-August-2025 |
| NUCLEUSRX, INC. |
Development of a Virtual Health Care Platform to reduce emergency re-hospitalizations in Heart Failure Patients transitioning from hospital to home |
RAKHIT, ASHOK |
NHLBI |
EAST WINDSOR |
NJ |
31-August-2025 |
| FIBROBIOLOGICS, LLC |
Development of a Novel Therapeutic Agent for Skin Fibrosis |
BOGATKEVICH, GALINA S |
NIAMS |
CHARLESTON |
SC |
31-August-2025 |
| GELSANA THERAPEUTICS, INC. |
Advancing Diabetic Foot Ulcer Treatment with Provasliex, a Controlled PDGF Release Hydrogel for Promoting Vascularization and Managing Overactive Inflammation |
ROCKER, ADAM |
NIDDK |
AURORA |
CO |
31-August-2025 |
| ANCILIA, INC. |
Enhancing E. coli Nissle colonization with CRISPR-Cas immunity |
FOLEY, MATTHEW HARRISON |
NIDDK |
NEW YORK |
NY |
31-August-2025 |
| ACPHARIS, INC. |
Algorithm and software for predicting the structure and degrading efficiency of PROTACs |
BEGLOV, DMITRI |
NIGMS |
HOLLISTON |
MA |
31-August-2025 |
| FOLI BIO INC. |
Non-invasive exfoliome platform to accelerate treatment for gastrointestinal disorders |
HUANG, YIMING |
NIDDK |
NEW YORK |
NY |
31-August-2025 |
| CYRUS BIOTECHNOLOGY, INC. |
Advanced Uricase Engineering for Improved Outcomes in Gout Patients |
CHAN, KUI KIU |
NIAMS |
SEATTLE |
WA |
31-August-2025 |
| RESONANT THERAPEUTICS, INC. |
Development of a Novel Nectin Targeting Antibody-drug Conjugate for Ovarian Cancer Therapy |
DELGADO, OLIVER |
NCI |
Santa Barbara |
CA |
31-August-2025 |
| ODMR TECHNOLOGIES, INC. |
Diamond quantum sensor for magnetoencephalography |
JARMOLA, ANDREJS |
NIBIB |
EL CERRITO |
CA |
31-August-2025 |
| OBJECTIVE BIOTECHNOLOGY, INC. |
Machine vision guided robotics for automated microinjections into fruit fly embryos |
ALEGRIA, ANDREW D |
OD |
MINNEAPOLIS |
MN |
31-August-2025 |
| FIBROPLATE, INC. |
Fibrinogen-coated albumin nanospheres for mitigation of irradiation-induced wound healing impairment in breast cancer patients. |
YEN, RICHARD |
NCI |
LAS VEGAS |
NV |
31-August-2025 |
| BOULDER CARE, INC. |
Right Tools, Right Time, Right Place: Telehealth for Opioid Use Disorder in Vulnerable Settings |
PAPES, STEPHANIE |
NIDA |
Portland |
OR |
31-August-2025 |
| ENDOTAT BIOTECHNOLOGIES LLC |
Next-generation Tissue-Adhesive Endoscopic Tattoo Ink |
REGE, KAUSHAL |
NIDDK |
PHOENIX |
AZ |
31-August-2025 |
| BIOSPYDER TECHNOLOGIES, INC. |
Whole blood filter paper assay for Alzheimers Disease |
SELIGMANN, BRUCE E. |
NIA |
CARLSBAD |
CA |
31-August-2025 |
| PROACTIVE MEMORY SERVICES, INC. |
CUSTOMIZABLE TRAINING SOFTWARE FOR PROFESSIONAL ALZHEIMER DIRECT CARE PROVIDERS |
FOSTER, NORMAN LOUIS |
NIA |
SALT LAKE CITY |
UT |
31-August-2025 |
| EINSENCA INC. |
PET Imaging of Damaging Neuroinflammation in Alzheimer's Disease |
LARSON, ANDREW CHRISTIAN |
NIA |
DOVER |
DE |
31-August-2025 |
| REVEAL PHARMA |
Fibrogenesis Targeted Manganese Based MRI Contrast Agent |
HOFFMAN, VERA |
NIDDK |
CAMBRIDGE |
MA |
31-August-2025 |
| PACDNA LLC |
Molecular brush-conjugated antisense oligonucleotide as a pan-KRAS depletion agent |
ZHANG, KE |
NCI |
NATICK |
MA |
31-August-2025 |
| LEFLORE TECHNOLOGIES, LLC |
Renal Therapeutic Angiogenesis Using the Novel Biologic ELP-VEGF |
BIDWELL, GENE LEFLORE |
NIDDK |
Brandon |
MS |
31-August-2025 |
| ATOMO, INC |
Finding undiagnosed ATTR-CM patients using AI technology in clinical settings |
MYERS, KELLY D |
NHLBI |
WEST LAKE HILLS |
TX |
31-August-2025 |
| PROACTIVE MEMORY SERVICES, INC. |
CUSTOMIZABLE TRAINING SOFTWARE FOR PROFESSIONAL ALZHEIMER DIRECT CARE PROVIDERS |
FOSTER, NORMAN LOUIS |
NIA |
SALT LAKE CITY |
UT |
31-August-2025 |
| SIMULATIONS PLUS, INC. |
Improving Similarity Scoring in Drug Discovery: Solving by Solvating |
JONES, JEREMY O |
NIGMS |
LANCASTER |
CA |
31-August-2025 |
| ADIUTRIX THERAPEUTICS |
Platform technology to identify and develop first-in-class anti-fibrotic therapeutics through inhibition of collagen CP4H |
LENNOX, RONALD |
NHLBI |
NEW YORK |
NY |
31-August-2025 |
| ACCELERATED MUSCLE BIOTECHNOLOGIES CONSULTANTS, L.L.C. |
Expanding synchrotron applications in biomedical research: Myocardial and skeletal muscle imaging at Brookhaven National Labs |
NGUYEN, KHOI DAC |
NIGMS |
Mansfield |
MA |
31-August-2025 |
| BIOSPYDER TECHNOLOGIES, INC. |
Whole blood filter paper assay for Alzheimers Disease |
SELIGMANN, BRUCE E. |
NIA |
CARLSBAD |
CA |
31-August-2025 |
| TENVOS INC. |
Remote and Non-Invasive Opioid Use Screening to Lower Barriers to Substance Use Disorder Diagnosis and Treatment |
SEIILOVA-OLSON, RIMA |
NIDA |
West Sacramento |
CA |
31-August-2025 |
| MCM6 THERAPEUTICS, INC. |
High-Content Screen to Identify Small Molecule Therapeutics that Reduce Aberrant Lipid Accumulation in APOE4 Alzheimer's Disease |
LAM, KELVIN T |
NIA |
LEXINGTON |
MA |
31-August-2025 |
| RAYDIANT OXIMETRY, INC. |
Advancing Fetal Assessment during Labor with Transabdominal Fetal Oximetry |
RAY, NEIL PADHARIA |
NICHD |
MOUNTAIN VIEW |
CA |
31-August-2025 |
| SAVIOR BRAIN INC. |
A youth-specific helmet for preventing traumatic brain injury |
AVERY, GORDON |
NINDS |
Vienna |
VA |
31-August-2025 |
| HELIXOMER, INC. |
Development of an RNA-based anticoagulant and antidote for precise on/off coagulation control during cardiovascular procedures |
KRISSANAPRASIT, ABHICHART |
NHLBI |
HILLSBOROUGH |
NC |
31-August-2025 |
| VINCERE BIOSCIENCES, INC. |
In vivo Evaluation of USP30 Inhibitors in Models Relevant to Parkinson's Disease |
BEHROUZ, BAHAREH |
NINDS |
Cambridge |
MA |
31-August-2025 |
| CUREBIOTECH, INC. |
Combination of CB101 and radiation therapy in head and neck squamous cell carcinoma |
SCHURE, LOUIS I |
NCI |
Philadelphia |
PA |
31-August-2025 |
| BEDROCK THERAPEUTICS, INC. |
Rational design of AAV vectors with human hepatocyte tropism and neutralizing antibody evasion |
LI, CHENGWEN |
NIDDK |
CHAPEL HILL |
NC |
31-August-2025 |
| THEIA IMAGING LLC |
Ultrahigh Speed OCT Angiography System for Patients who are Unable to Cooperate |
VIEHLAND, CHRISTIAN |
NEI |
CHAPEL HILL |
NC |
31-August-2025 |
| FLUIDISPEC LLC |
A Microfluidic/Nanofluidic System for Rapid Single Cell Proteomics |
TIMPERMAN, AARON T |
NIGMS |
PHILADELPHIA |
PA |
31-August-2025 |
| AQUALUNG THERAPEUTICS CORP. |
A Randomized Phase 2A Clinical Trial Pioneering the Utility of an eNAMPT-Reducing Therapy in ARDS/VILI: the PUERTA Trial |
GARCIA, JOE G. N. |
NHLBI |
Juno Beach |
FL |
31-August-2025 |
| FLINT REHABILITATION DEVICES |
FitMi AD: a safe and motivating computer-guided exercise system for individuals with MCI or mild dementia due to Alzheimer's disease |
ZONDERVAN, DANIEL |
NIA |
IRVINE |
CA |
31-August-2025 |
| EXQOR TECHNOLOGIES, INC. |
New targeted BDNF nanoparticles for treatment of METH addiction and neurotoxicity |
VITALIANO, FRANCO |
NIDA |
BOSTON |
MA |
31-August-2025 |
| A AND G PHARMACEUTICAL, INC. |
A Circulating Biomarker for use in Monitoring Metastatic Breast Cancer |
SERRERO, GINETTE |
NCI |
COLUMBIA |
MD |
31-August-2025 |
| ALGEN BIOTECHNOLOGIES INC |
AlgenML: Drug target discovery platform for transcriptional reprogramming of MYCN-driven neuroblastoma |
HUANG, CHUN-HAO |
NIGMS |
SAN FRANCISCO |
CA |
31-August-2025 |
| LINSHOM MEDICAL INC |
Advanced Prediction of Emerging Respiratory Decline with the Linshom Continuous Predictive Respiratory Sensor (CPRS) |
FELDMAN, RONEN |
NHLBI |
ELLICOTT CITY |
MD |
31-August-2025 |
| BIOSENSICS, LLC |
Software Platform for Automatic, Opportunistic Screening of Vertebral Compression Fractures |
VAZIRI, ASHKAN |
NIA |
Newton |
MA |
31-August-2025 |
| SAROS THERAPEUTICS INC |
Process Development and Preclinical Advancement of a Novel Nanoparticle Formulation for Immune Activation |
JOHNSON, RICHARD |
NCI |
CHICAGO |
IL |
31-August-2025 |
| CERIA THERAPEUTICS, INC. |
Targeting inflammation and oxidative stress to treat acute lung injury with CNP-miR146a |
JACKSON, DAVID |
NHLBI |
Tucson |
AZ |
31-August-2025 |
| GENERAL BIOPHYSICS, LLC |
Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects |
ILIN, ILYA |
NIA |
WAYLAND |
MA |
31-August-2025 |
| AIQ SOLUTIONS, INC. |
Comprehensive Assessment of Cancer Theranostics Response |
PERK, TIMOTHY |
NCI |
MADISON |
WI |
31-August-2025 |
| GMJ TECHNOLOGIES, INC. |
Sodium Dodecyl Sulfate Removal Interface to Enable Characterization of Fragment Impurities in Monoclonal Antibodies by Capillary Electrophoresis Sodium Dodecyl Sulfate Coupled to Mass Spectrometry |
DADA, OLUWATOSIN |
NIGMS |
EVERETT |
WA |
31-August-2025 |
| PANORAMA RESEARCH, INC. |
Novel therapy for arthrofibrosis |
LARRICK, JAMES W |
NIAMS |
SUNNYVALE |
CA |
31-August-2025 |
| CYION TECHNOLOGIES, LLC |
An in vitro electrophysiology system for high-throughput measurement of cardiomyocyte action potential |
JIANG, XIN |
NHLBI |
PLEASANTON |
CA |
31-August-2025 |
| DELFINA CARE INC. |
A machine learning based fetal monitoring system to predict and prevent fetal hypoxia. |
ZELL, BONNIE LESLEY |
NICHD |
San Jose |
CA |
31-August-2025 |
| EDVOTEK, INC. |
The EdvoReader: Developing a Quantitative PCR and Colorimetry Instrument for Laboratory Skills Training |
ELL, BRIAN |
NIGMS |
WASHINGTON |
DC |
31-August-2025 |
| RYTEK MEDICAL, INC. |
Ultrasound-coupled Electrical Impedance Tomography for Sarcopenia Assessment |
HALTER, RYAN JOSEPH |
NIA |
LEBANON |
NH |
31-August-2025 |
| VIRTUOSO SURGICAL, INC. |
A Robotic System to Remove Bladder Tumors Intact: The Key to Making Lifesaving Treatment Decisions |
HENDRICK, RICHARD JOSEPH |
NIBIB |
NASHVILLE |
TN |
31-August-2025 |
| ANELLEO, INC. |
Innovative 3D Printed Intravaginal Ring AnelleO-PRO, the first Single Administration of Progesterone for Infertility |
JANUSZIEWICZ, RIMA |
NICHD |
CHAPEL HILL |
NC |
31-August-2025 |
| FURANICA, INC. |
Structurally engineered N-acyl amino acids for the treatment of NASH |
SCHOPFER, FRANCISCO JOSE |
NIDDK |
Pittsburgh |
PA |
31-August-2025 |
| AUTONOMOUS HEALTHCARE, INC. |
Using Machine Learning and Blockchain Technology to Reduce Drug Diversion in Hospitals |
GHOLAMI, BEHNOOD |
NIDA |
Santa Clara |
CA |
31-August-2025 |
| BIOSPUTNIK LLC |
miRNA-Nanotechnology as a novel regenerative therapy for lymphangioleiomyomatosis |
PLEIMES, DIRK |
NHGRI |
NEW YORK |
NY |
31-August-2025 |
| PRAEVENTIX, LLC |
IND Enabling Studies for the Development of Pruritus Therapeutic PRA-523 |
PIPPIN, DOUGLAS ANTHONY |
NIAMS |
EXTON |
PA |
31-August-2025 |
| LINK BIOSYSTEMS INC. |
EFFICIENT DIFFERENTIATION, SCALE-UP, AND MATURATION OF IPS DERIVED CARDIOMYOCYTES |
RONALDSON, KACEY |
NHLBI |
IRVINGTON |
NY |
31-August-2025 |
| NEURINSIGHT, LLC |
Towards intra-operative guidance in brain tumor surgery using real-time resting-state functional MRI |
DENNIG, DIETER W |
NINDS |
ALBUQUERQUE |
NM |
31-August-2025 |
| INDELIBLE LEARNING, INC. |
Interactive hand hygiene training for special education pre-vocational students |
CRILEY, JASMINKA |
NICHD |
PALOS VERDES ESTATES |
CA |
31-August-2025 |
| SPATIAL GENOMICS, INC. |
Spatial genomics analysis of tumor samples |
FRIEDA, KIRSTEN |
NCI |
Pasadena |
CA |
31-August-2025 |
| LARIX BIOSCIENCE, LLC |
Therapy for ectopic calcification in pseudoxanthoma elasticum |
MENDELSOHN, ANDREW R |
NIAMS |
SUNNYVALE |
CA |
31-August-2025 |
| SXRNA TECHNOLOGIES, INC. |
Creating an sxRNA Organoid Product for Advancing the Study, Prevention and Treatment of Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) |
TENENBAUM, SCOTT |
NIA |
ALBANY |
NY |
31-August-2025 |
| NEUROCOMP SYSTEMS, INC. |
Assessment Validation |
O'HALLORAN, JAMES P |
NIA |
Laguna Woods |
CA |
31-August-2025 |
| BIOSTRATEGIES, LC |
Gene Therapy that Systemically Produces Brain-penetrating Replacement Enzyme for MPS IIIA (Sanfilippo A Syndrome) |
PATTADA, SHIVAKUMAR DEVAIAH |
NINDS |
STATE UNIVERSITY |
AR |
31-August-2025 |
| MOLECULAR TARGETING TECHNOLOGIES, INC. |
Instantaneous Tumor Spray for Real-Time Surgical Guidance |
GRAY, BRIAN DAVID |
NCI |
WEST CHESTER |
PA |
31-August-2025 |
| EPICYPHER, INC. |
Development of a high-throughput epigenomic mapping platform to molecularly phenotype Crohn's disease |
JOHNSTONE, ANDREA LYNN |
NIDDK |
Research Triangle Park |
NC |
31-August-2025 |
| WAVI COMPANY |
Development of an AI-empowered device that utilizes multimodal data-visualization to aid in the diagnosis, and treatment, of OUD |
OAKLEY, DAVID |
NIDA |
Englewood |
CO |
31-August-2025 |
| EMITECH, INC. |
Wearable sensor for opioids detection based on electrochemical sensor arrayintegrated with Bluetooth device |
LEVITSKY, IGOR A |
NIDA |
FALL RIVER |
MA |
31-August-2025 |
| TRAMPOLINE PHARMA, INC. |
Next Generation Autologous TIL Cancer Therapy: Development of GMP manufacturing process |
DUKE, RICHARD C |
NCI |
AURORA |
CO |
31-August-2025 |
| PICOYUNE |
Plasmonic sensor and field monitor for mercury |
JAMES, JAY |
NIEHS |
BERKELEY |
CA |
31-August-2025 |
| EVIDENCE-BASED PRACTICE INSTITUTE, INC. |
Treating Drivers of Suicide in Primary Care using Jaspr Health |
DIMEFF, LINDA A |
NIAAA |
SEATTLE |
WA |
31-August-2025 |
| THERANOVA, LLC |
A novel enteral feeding system for the earlier and safer delivery of enteral nutrition through continuous monitoring of tip location |
BURNETT, DANIEL ROGERS |
NIA |
SAN FRANCISCO |
CA |
31-August-2025 |
| IVEENA DELIVERY SYSTEMS, INC. |
Topical Eyedrops Increasing Lysyl Oxidase Activity to Control Myopia |
MOLOKHIA, SARAH ABDULLA |
NEI |
SALT LAKE CITY |
UT |
31-August-2025 |
| TDA RESEARCH, INC. |
Advanced Pediatric Airway Trainer for Enhanced Clinical Education in Pediatric Critical Care |
SRINIVAS, GIRISH |
NICHD |
GOLDEN |
CO |
31-August-2025 |
| I-CORDIS, LLC |
Development of a Novel Immunomodulatory Pyridone for the Treatment of Heart Failure with Preserved Ejection Fraction |
BALTZ, JENNIFER |
NHLBI |
SAINT LOUIS |
MO |
31-August-2025 |
| LEFLORE TECHNOLOGIES, LLC |
Renal Therapeutic Angiogenesis Using the Novel Biologic ELP-VEGF |
BIDWELL, GENE LEFLORE |
NIDDK |
Brandon |
MS |
31-August-2025 |
| MIGRA-THERAPEUTICS, LLC |
Translational Development of a Targeted and Stroma-penetrating Nanoparticle Drug for Pancreatic Cancer Therapy |
ZHU, LEI |
NCI |
Atlanta |
GA |
31-August-2025 |
| EKO DEVICES, INC. |
Deep learning for algorithmic detection of pulmonary hypertension using a combined digital stethoscope and single-lead electrocardiogram |
VENKATRAMAN, SUBRAMANIAM |
NHLBI |
OAKLAND |
CA |
31-August-2025 |
| FLUID DISCOVERY INC |
A universal droplet microfluidic platform for ultrahigh-throughput biocatalyst evolution |
PRINCE, ROBIN |
NIGMS |
San Francisco |
CA |
31-August-2025 |
| MUCOMMUNE, LLC |
IND‐enabling development of MM‐008 IVR, an antibody-based nonhormonal contraceptive intravaginal ring |
CONE, RICHARD |
NICHD |
Morrisville |
NC |
31-August-2025 |
| MICROVI BIOTECH, INC. |
Intensified, High-Rate Reductive Immobilization of Hexavalent Chromium |
SHIRAZI, FATEMEH |
NIEHS |
HAYWARD |
CA |
31-August-2025 |
| NEUTHERAPEUTICS, LLC |
PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health |
RINEHART, JOHN |
NIA |
TUCSON |
AZ |
31-August-2025 |
| DENOVX, LLC |
Advanced Nucleation Technologies for Membrane Protein Crystallization to Accelerate Structure-Based Drug Design for Substance Use Disorders |
BOND, ANDREW H. |
NIDA |
STREAMWOOD |
IL |
31-August-2025 |
| FUNCTION PROMOTING THERAPIES, LLC |
Phase IIB: Development of TruT Algorithm for Commercialization in Androgen Disorders |
JASUJA, RAVI |
NIA |
BOSTON |
MA |
31-August-2025 |
| BIONIC SKINS LLC |
Improving the health status of dysvascular amputees by deploying digital prosthetic interface technology in combination with exercise intervention |
TURNER, TROY ALLEN |
NICHD |
LEBANON |
NH |
31-August-2025 |
| ASTER LABS, INC. |
Automated Contact Tracing System for Rapid High-Accuracy Assessment to Management Dementia Patients and Staff Exposed to Infectious Diseases in Long Term Care Facilities |
SHEIKH, SUNEEL ISMAIL |
NIA |
Shoreview |
MN |
31-August-2025 |
| HIGHLAND INSTRUMENTS, INC. |
Noninvasive Brain Stimulation for Treating Addiction |
WAGNER, TIMOTHY ANDREW |
NIDA |
CAMBRIDGE |
MA |
31-August-2025 |
| ALLANDER BIOTECHNOLOGIES, INC. |
IND-enabling toxicology studies to reach IND approval for a proprietary biologic to treat oral mucositis in cancer patients |
YOUNG, CHRISTIAN |
NIDCR |
AURORA |
CO |
31-August-2025 |
| ORSOBIO, INC. |
TLC-1235, a controlled-release mitochondrial protonophore (CRMP), for the reversal of insulin resistance in patients with severe lipodystrophy |
MYERS, ROBERT PAUL |
NIDDK |
Menlo Park |
CA |
31-August-2025 |
| CELDARA MEDICAL, LLC |
Anti-hIAPP for the preservation of pancreatic function in Type 2 Diabetes |
MURAD, JOANA M |
NIDDK |
LEBANON |
NH |
31-August-2025 |
| STRATAGEN BIO, INC. |
Minimally invasive quantitative tissue oxygen sensors to personalize cancer care |
EKCHIAN, GREGORY |
NCI |
CAMBRIDGE |
MA |
31-August-2025 |
| VIGOROUS MIND, INC. |
Autonomous Navigating Robot for Detecting Falls and Risk of Falls in Nursing Home Residents with Alzheimer's Disease /ADRD |
MALINSKY, YUVAL |
NIA |
NEWTON |
MA |
31-August-2025 |
| REVEAL PHARMA |
Fibrogenesis Targeted Manganese Based MRI Contrast Agent |
HOFFMAN, VERA |
NIDDK |
CAMBRIDGE |
MA |
31-August-2025 |
| GISMO THERAPEUTICS, INC. |
Amyloid-Beta and Tau/Glycosaminoglycan Dual Inhibitor for Alzheimer's Disease |
GREGOR, PAUL |
NIA |
HOWARD BEACH |
NY |
31-August-2025 |
| INGENIOUS TARGETING LABORATORY, INC. |
Research and Development to Establish a Small Animal Model as a Significant Resource of High-Value Single-Domain Antibodies |
KIRILOV, MILEN |
NIAID |
RONKONKOMA |
NY |
31-August-2025 |
| KLEIN BUENDEL, INC. |
SSW Works: A Virtual Learning Environment for Occupational Skin Cancer Prevention |
BULLER, MARY K |
NCI |
GOLDEN |
CO |
31-August-2025 |
| VIRTUALLY BETTER, INC. |
Disseminable Evidence-Based Treatment for the Dental Office: Virtual Exposure Tools for Dental Fear - neVR Fear the Dentist |
ADAMS LARSEN, MARGO |
NIDCR |
DECATUR |
GA |
31-August-2025 |
| PEROSPHERE TECHNOLOGIES INC. |
Novel Broad-Spectrum Point-of-Care Coagulometer |
BAKHRU, SASHA H |
NHLBI |
DANBURY |
CT |
31-August-2025 |
| KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT |
Care Assistant for Family Caregivers of Persons with Dementia During Out of the Home Activities |
ANDERSON, SHANE M. |
NIA |
Minneapolis |
MN |
31-August-2025 |
| AKELOS INC. |
Optimization of an HCN1-Selective Inverse Agonist for the Treatment of Peripheral Neuropathic Pain |
FOX, STEVEN R |
NINDS |
NEW YORK |
NY |
31-August-2025 |
| OLIGOMERIX, INC |
A 26-week rat toxicity study and efficacy and biomarker studies in Tau-APP Alzheimer's mouse model to support a Phase 1b clinical study |
MOE, JAMES G. |
NIA |
White Plains |
NY |
31-August-2025 |
| GIGAMUNE, INC. |
Delivery of Full Length Dystrophin to Muscle Cells for DMD Gene Therapy |
JOHNSON, DAVID SCOTT |
NIAMS |
SAN FRANCISCO |
CA |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Hand Tremor Compensation Approach for Touch Screens |
KRAMER, KEVIN M. |
NIA |
SAINT PAUL |
MN |
31-August-2025 |
| CANGET BIOTEKPHARMA, LLC |
Perform non-GLP and GLP TOX/TK studies, and file a novel drug IND with the FDA for advanced pancreatic cancer patient clinical trials |
LING, XIANG |
NCI |
BUFFALO |
NY |
31-August-2025 |
| COLLABORATIONS PHARMACEUTICALS, INC. |
MegaTrans – human transporter machine learning models |
EKINS, SEAN |
NIGMS |
FUQUAY VARINA |
NC |
31-August-2025 |
| CELDARA MEDICAL, LLC |
Preclinical development of CM-CX1 for the treatment of ovarian clear cell and renal cell carcinomas |
MURAD, JOANA M |
NCI |
LEBANON |
NH |
31-August-2025 |
| BIOTHERAPEUTICS, INC. |
Novel first-in-class Therapeutics for Rheumatoid Arthritis |
BASSAGANYA-RIERA, JOSEP |
NIAMS |
BLACKSBURG |
VA |
31-August-2025 |
| PARTILLION BIOSCIENCE CORPORATION |
Linking antibody sequences to function at the single-cell level using nanovial technology |
DE RUTTE, JOSEPH |
NIGMS |
LOS ANGELES |
CA |
31-August-2025 |
| DROPLETPHARM INC. |
Production of radiometal-based radiopharmaceuticals at a clinical scale via droplet-scale radiochemistry |
JONES, JASON |
NIBIB |
SHERMAN OAKS |
CA |
31-August-2025 |
| BIOSPUTNIK LLC |
Novel Combination Therapy for Treatment and Prevention of PulmonaryLymphangioleiomyomatosis (LAM) and Tuberous Sclerosis Complex (TSC) |
PLEIMES, DIRK |
NHLBI |
NEW YORK |
NY |
31-August-2025 |
| PARABON NANOLABS, INC. |
Novel whole-genome analysis methods for Alzheimer's risk prediction |
GREYTAK, ELLEN MCRAE |
NIA |
RESTON |
VA |
31-August-2025 |
| BIOLOGICAL MIMETICS, INC. |
Development of a Staph Aureus Vaccine |
DOLLERY, STEPHEN JEFFREY |
NIAID |
FREDERICK |
MD |
31-August-2025 |
| XLOCK BIOSCIENCES, LLC |
Targeting the CCR6-CCL20 pathway for treatment of psoriatic joint and entheseal inflammation |
CLARKE, WILLIAM R |
NIAMS |
MUSKEGO |
WI |
31-August-2025 |
| ALUME BIOSCIENCES, INC. |
Development of ALM-488 for nerve and ureter visualization during abdominal surgery |
WHITNEY, MICHAEL A |
NCI |
San Diego |
CA |
31-August-2025 |
| QUADRIDOX, INC. |
Development and evaluation of a combined X-ray transmission and diffraction imaging system for pathology |
GREENBERG, JOEL |
NIBIB |
DURHAM |
NC |
31-August-2025 |
| NUMENTUS TECHNOLOGIES INC. |
High-speed hyperspectral imaging for highly multiplexed immunofluorescence imaging |
FARIS, GREGORY W |
NIMH |
MENLO PARK |
CA |
31-August-2025 |
| TRICORDER ARRAY TECHNOLOGIES, LLC |
Tricorder Array Technologies Animal Welfare Sensor |
TINDAL, ROBERT JOHN |
OD |
BIRMINGHAM |
AL |
31-August-2025 |
| IF, LLC |
Development of a Photoacoustic Quantitative Ultrasound (PAQUS) device for clinical use |
MORRIS, RICHARD FRANKLIN |
NIAMS |
STOUGHTON |
WI |
31-August-2025 |
| KEYSTONE NANO, INC. |
Ceraxa (Ceramide NanoLiposome) and Vinblastine For the Improved Treatment of Relapsed or Refractory Acute Myeloid Leukemia |
ADAIR, BERNADETTE MCMAHON |
NCI |
State College |
PA |
31-August-2025 |
| KANNALIFE SCIENCES, INC. |
Development of KLS-13019 for Neuropathic Pain |
BRENNEMAN, DOUGLAS ERIC |
NINDS |
Lloyd Harbor |
NY |
31-August-2025 |
| PRONEUROGEN, INC. |
GMP Manufacturing and IND Enabling Studies of Extended-Release PNA5: A Novel Therapeutic for Treating Cognitive Impairment in Patients at-risk for Alzheimer's Disease-Related Dementias and Vascular |
RILEY, JEREMY |
NIA |
TUCSON |
AZ |
31-August-2025 |
| SHEARIT, LLC |
Extending the Ischemic Penumbra in Large Vessel Occlusion Stroke |
NEMOTO, EDWIN M |
NINDS |
ALBUQUERQUE |
NM |
31-August-2025 |
| 3P BIOTECHNOLOGIES, INC. |
Trans Spinal Delivery of a Targeted Nanoformulation of Curcuminoids to Treat AD |
GUPTA, RAMESH C |
NIA |
PROSPECT |
KY |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Intuitive Child Safety Seat to Increase Security |
SEIFERT, SARA |
NICHD |
SAINT PAUL |
MN |
31-August-2025 |
| NANOMETICS, LLC |
A Phase 2, randomized, double-blind, 4-arm, multicenter study to demonstrate the efficacy and safety of topical dosage formulations of a prescription drug product for actinic keratosis |
ISAACMAN, STEVEN |
NCI |
La Jolla |
CA |
31-August-2025 |
| LIFEBIO INC |
LifeBioTALK: Digital Engagement with a Pre-Scripted Avatar for People with Alzheimer's Disease to Reduce Challenging Behaviors and Caregiver Burden |
SANDERS, LISBETH |
NIA |
MARYSVILLE |
OH |
31-August-2025 |
| VERSAPEUTICS INC |
Developing therapeutic antibodies for Alzheimer's disease |
SUN, MIAO |
NIA |
SAN DIEGO |
CA |
31-August-2025 |
| AMYDIS DIAGNOSTICS, INC. |
Use of novel fluorescent tracers to develop a comprehensive retinal biomarker database that maps the heterogeneity of Alzheimer's pathogenesis |
SARRAF, STELLA |
NIA |
La Jolla |
CA |
31-August-2025 |
| INOVCARES CONNECTED COMPREHENSIVE HEALTHCARE CORPORATION |
Efficacy of a culturally-sensitive telehealth platform in fostering community-based care coordination for respectful maternal mental health |
KAMARA, MOHAMED |
NINR |
SILVER SPRING |
MD |
31-August-2025 |
| POINT DESIGNS, LLC |
The Point Powered: A Robust Actuated Prosthetic Finger for Partial Hand Amputation |
SLIKER, LEVIN |
NIBIB |
Lafayette |
CO |
31-August-2025 |
| ARAVIS BIOTECH, LLC |
The X-VISUAL (X-ray Visualized Indicator for Screw-strain Under Applied Load) |
LATOUR, ROBERT A |
NIAMS |
GREENVILLE |
SC |
31-August-2025 |
| HIGHLAND INSTRUMENTS, INC. |
Commercial Readiness in CTS Pain Management |
WAGNER, TIMOTHY ANDREW |
NIAMS |
CAMBRIDGE |
MA |
31-August-2025 |
| HEMEX HEALTH, INC. |
Using an Inclined Plane System to Triage TBI Patients |
GALEN, PETER |
NINDS |
Portland |
OR |
31-August-2025 |
| CYTEX THERAPEUTICS INC. |
Addressing bone marrow lesions that compromise osteochondral tissue repair |
WILLARD, VINCENT P |
NIAMS |
DURHAM |
NC |
31-August-2025 |
| ARCASCOPE, INC |
Feasibility of app-delivered circadian synchronization therapy with light in a cohort of pregnant women |
WALCH, OLIVIA |
NICHD |
CHANTILLY |
VA |
31-August-2025 |
| IRIS KINETICS INC |
A Spatially Uniform Illumination Source for Widefield Multi-Spectral Optical Imaging |
SEYMOUR, ELIF |
NINDS |
BOSTON |
MA |
31-August-2025 |
| INFOTECH SOFT, INC. |
Deep-CDS: Deep Learning Semantic Data Lake for Clinical Decision Support |
KABUKA, MANSUR R. |
NIGMS |
MIAMI |
FL |
31-August-2025 |
| VIRTUS THERAPEUTICS CORPORATION |
PANK Activators for the treatment of pantothenate kinase-associated neurodegeneration |
REGAN, JESSICA |
NINDS |
Groton |
CT |
31-August-2025 |
| KEYBIOME INC |
Aim protein-based anti-inflammatory therapeutic for the treatment of IBD |
POHL ROBINSON, CATHERINE |
NIDDK |
Eugene |
OR |
31-August-2025 |
| IOTAMOTION, INC. |
Development of a Micro-Mechanical Insertion Tool with Intraoperative Real-Time Electrophysiological Sensing Control for Cochlear Implantation |
NIKOU, CONSTANTINOS |
NIDCD |
Vadnais Heights |
MN |
31-August-2025 |
| IVEENA DELIVERY SYSTEMS, INC. |
Topical Eyedrop Therapy for Keratoconus |
MOLOKHIA, SARAH ABDULLA |
NEI |
SALT LAKE CITY |
UT |
31-August-2025 |
| NASONI LLC |
Access-H20: Sensor driven smart faucet to enable and empower independent drinking and grooming for individuals impacted by spinal cord injury |
WADDELL, JOHN STEVEN |
NICHD |
SUFFOLK |
VA |
31-August-2025 |
| SANAHEAL, INC. |
Strain-Programmed Bioadhesive Patch for Enhanced Diabetic Wound Healing |
YUK, HYUNWOO |
NIDDK |
Cambridge |
MA |
31-August-2025 |
| AETON THERAPEUTICS, INC. |
Acetylated Tau Immunotherapy for Alzheimer's Disease |
SINHA, ANJANA |
NIA |
BURLINGAME |
CA |
31-August-2025 |
| COVIRA SURGICAL |
Preventing chemotherapy-related toxicities and infections with a novel phosphorylated triblock copolymer |
ALVERDY, JOHN C |
NCI |
NORTH CHICAGO |
IL |
31-August-2025 |
| TURTLETREE LABS INC. |
Evaluation of recombinant bovine lactoferrin and N-linked glycan effects on infant gut health and immunity |
FEHER CASTAGNA, VANESSA PATRICIA |
NICHD |
WOODLAND |
CA |
31-August-2025 |
| LARIX BIOSCIENCE, LLC |
Overcoming pressure ulcers with engineered hormones and stem cells |
HU, MICKEY |
NIA |
SUNNYVALE |
CA |
31-August-2025 |
| LIBERATING TECHNOLOGIES, INC. |
Unintrusive Pediatric Logging Orthotic Adherence Device: UPLOAD |
FARRELL, TODD RICHARD |
NICHD |
HOLLISTON |
MA |
31-August-2025 |
| MERIDIAN BIOTECH, LLC |
Development and Production of Standardized Reference Diets for Zebrafish Research |
CORACE, DONALD |
OD |
WOODLANDS |
TX |
31-August-2025 |
| EVRYS BIO, LLC |
A single antiviral to treat multiple opportunistic infections |
REMISZEWSKI, STACY |
NIAID |
DOYLESTOWN |
PA |
31-August-2025 |
| GENETIVISION CORPORATION |
A Conditional Loss-of-Function Mutation Collection in Drosophila |
TAN, YING |
NIGMS |
HOUSTON |
TX |
31-August-2025 |
| TEGA THERAPEUTICS, INC. |
Title: Development and Validation of Therapy for GM1 Gangliosidosis |
BROWN, JILLIAN R |
NINDS |
LA JOLLA |
CA |
31-August-2025 |
| PSYC TECH, LTD |
Finalizing and Testing an Online Therapist Training and Assistance Program to Facilitate Implementation of Comprehensive Behavioral Intervention for Tic Disorders (CBIT-Trainer) |
MOUTON-ODUM, SUZANNE |
NIMH |
HOUSTON |
TX |
31-August-2025 |
| NEURAL DYNAMICS TECHNOLOGIES INC. |
Designing low-cost, customizable high-density probes for acute and chronic neural recordings in rodents |
VAN WELIE, INGRID |
NIMH |
NEWTON |
MA |
31-August-2025 |
| BIOMEDICAL DEVELOPMENT CORPORATION |
mHealth for Patient Self-Management of Opioid Use Disorder |
POTTER, JENNIFER SHARPE |
NIDA |
Lexington |
KY |
31-August-2025 |
| AMBERGEN, INC |
Photocleavable Mass-Tags for Spatial Multiomics of Alzheimer’s Brain Tissue |
LIM, MARK |
NIA |
WATERTOWN |
MA |
31-August-2025 |
| CARDIAC RSK3 INHIBITORS, LLC |
PP2A Anchoring Disruptor Therapy in Heart Failure |
CIVIDINI, FEDERICO |
NHLBI |
LOS ALTOS |
CA |
31-August-2025 |
| SCARLESS LABORATORIES, INC. |
Novel peptide-impregnated hydrogel as a wound healing device |
ZHENG, ZHONG |
NIDCR |
BEVERLY HILLS |
CA |
31-August-2025 |
| INTEGRATED SENSORS, LLC |
Ultrafast and Precise External Beam Monitor for FLASH and Other Advanced Radiation Therapy Modalities |
FRIEDMAN, PETER S |
NCI |
PALM BEACH GARDENS |
FL |
31-August-2025 |
| MOLECULAR THERANOSTICS, LLC |
Commercialization of an MRI contrast agent for differential diagnosis of prostate cancer |
GAO, SONGQI |
NCI |
BEACHWOOD |
OH |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Modular Convertible Child Safety Seat to Improve Usage |
RYDBERG, NICK |
NICHD |
SAINT PAUL |
MN |
31-August-2025 |
| CAMBRIDGE POLYMER GROUP, INC. |
Preventing Pneuomothorax During Transthoracic Lung Biopsy |
SPIEGELBERG, STEPHEN HARRY |
NCI |
Woburn |
MA |
31-August-2025 |
| MIRO HEALTH INC |
The Proactive Screening and diagnosis of mild cognitive impairment and depression in patients aged 65 and over: An Implementation Study |
GLENN, SHENLY |
NIA |
Sacramento |
CA |
31-August-2025 |
| INTRINSIC LIFESCIENCES, LLC |
Novel Point-of-Care Device for Urinary Hepcidin to Detect Iron Deficiency in Children and Adolescents |
OSTLAND, VAUGHN E |
NIDDK |
LA JOLLA |
CA |
31-August-2025 |
| RECUPERO ROBOTICS LLC |
Rehabilitation Using Community-Based Affordable Robotic Exercise Systems (Rehab CARES) |
JOHNSON, MICHELLE J. |
NICHD |
PHILADELPHIA |
PA |
31-August-2025 |
| ATILA BIOSYSTEMS, INC. |
PROGRESS: PRevention of cervical cancer using the Genotyping scREening and Same-day Self-sampling |
WANG, YOUXIANG |
NCI |
Sunnyvale |
CA |
31-August-2025 |
| LEBRUN LABS, LLC |
A Nonanimal Test Method to Determine the Ocular Safety of Consumer Products and Chemicals: Commercialization |
LEBRUN, STEWART |
NIEHS |
ANAHEIM |
CA |
31-August-2025 |
| SPIKE NEURO LLC |
Addressing the wireless power problem: A low-power hybrid radio for neuroscience experiments |
GERTH, REBECCA JEANNE |
NIMH |
ANN ARBOR |
MI |
31-August-2025 |
| MINDTRACE TECHNOLOGIES, INC. |
Development of an innovative neurosurgical planning tool for awake craniotomy |
SIMS, MAXWELL HARRISON |
NIMH |
PITTSBURGH |
PA |
31-August-2025 |
| POTENTIOMETRIC PROBES, LLC |
Optimized Ratiometric Voltage-Sensitive Dyes for Cardiac Research, Safety Pharmacology |
ACKER, COREY |
NIGMS |
FARMINGTON |
CT |
31-August-2025 |
| QUELL TX, INC. |
BRITE-Eye: An integrated discovery engine for CNS therapeutic targets driven by high throughput genetic screens, functional readouts in human neurons, and machine learning |
WILLIAMS, LUIS ALBERTO |
NIMH |
CAMBRIDGE |
MA |
31-August-2025 |
| LASE INNOVATION INC. |
Time-lapse Flow Cytometry for Kinetic Profiling of T-Cell Function |
KWOK, SHELDON J.J. |
NCI |
Waltham |
MA |
31-August-2025 |
| RENERVA, LLC |
Restoration of Muscular Function Following Direct Muscle Neurotization |
SOLETTI, LORENZO |
NINDS |
PITTSBURGH |
PA |
31-August-2025 |
| INNOVATIVE DESIGN LABS, INC. |
Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals with Alzheimer Disease |
KABLAN, JOHN |
NIA |
MINNEAPOLIS |
MN |
31-August-2025 |
| ESPERIMAGE LLC |
Wearable modular high-density diffuse optical tomography |
TROBAUGH, JASON WAYNE |
NIMH |
SAINT LOUIS |
MO |
31-August-2025 |
| TALKSPACE LLC |
Message-based psychotherapy and digital treatment sequences for depression |
PADMANABHAN, AARTHI |
NIMH |
NEW YORK |
NY |
31-August-2025 |
| AKROTOME IMAGING, INC. |
Along the continuum for an IND: An In-Vivo large animal study for opticalimage guided surgery of spontaneous breast cancer. |
STRAIGHT, BRIAN |
NCI |
Charlotte |
NC |
31-August-2025 |
| ELECTRONIC BIOSCIENCES, INC. |
Point-of-Care Assay for Type 1 Diabetes Diagnosis and Prognostication |
ERVIN, ERIC |
NIDDK |
SAN DIEGO |
CA |
31-August-2025 |
| AQUALUNG THERAPEUTICS CORP. |
Preclinical Development of a Novel eNAMPT-Neutralizing mAb for Pulmonary Hypertension |
GARCIA, JOE G. N. |
NHLBI |
Juno Beach |
FL |
31-August-2025 |
| COBIO DIAGNOSTICS INC. |
Rapid phage-amplified immunoassay for phenotypic UTI diagnosis and antimicrobial susceptibility testing |
COX, CHRISTOPHER R |
NIDDK |
Aurora |
CO |
31-August-2025 |
| APIE THERAPEUTICS, INC. |
Development of Novel Small Molecule Anti-Fibrotic Agent for the Treatment of Systemic Scleroderma |
ALEGRIA, ESTHER M |
NHLBI |
CARY |
NC |
31-August-2025 |
| AMBERGEN, INC |
A Highly Multiplexed, Multiomic 3D Mouse Brain Map Using MALDI-IHC |
LIM, MARK |
NIMH |
WATERTOWN |
MA |
31-August-2025 |
| CRYOCRATE, LLC |
Innovation of Biobanking for Cellular Adoptive Immunotherapies Based on a First-in-Class Biocompatible Cryopreservation Technology for T and NK Cells and Their CAR-Engineered Products |
HAN, XU |
NCI |
COLUMBIA |
MO |
31-August-2025 |
| PERIOMICS CARE, LLC |
A Novel Remedy for Periodontal Bone Loss |
SAXENA, DEEPAK |
NIDCR |
NEW YORK |
NY |
31-August-2025 |
| PHYSICAL SCIENCES, INC |
Ultra-high speed AO-OCT clinical system to image ganglion cells and microglia |
MUJAT, MIRCEA |
NEI |
ANDOVER |
MA |
31-August-2025 |
| AMELIA TECHNOLOGIES, LLC |
Development of the UValidate platform for the profiling of topically applied chemical agents. |
SYKORA, PETER |
NIEHS |
WASHINGTON |
DC |
31-August-2025 |
| STEMLOOP, INC. |
A Paper-Based Synthetic Biology Platform for the On-Demand Testing of Water Quality |
ALAM, KHALID KAMAL |
NIEHS |
Evanston |
IL |
31-August-2025 |
| LIFEBOARD MEDICAL |
Leveraging Health Information Technology to Improve Trauma Resuscitation |
METZLER, MICHAEL H. |
NLM |
FORT COLLINS |
CO |
31-August-2025 |
| BRAINCHECK, INC. |
A novel platform to facilitate provider adoption of cognitive care planning |
HUANG, BIN |
NIA |
Austin |
TX |
31-August-2025 |
| RAESEDO, LLC |
Development of SP-A Derived Peptidomimetics for the Treatment of Asthma - Phase II |
LEDFORD, JULIE GUNNELLS |
NHLBI |
TUCSON |
AZ |
31-August-2025 |
| ACTUATED MEDICAL, INC. |
Active Disposable Cap for Endoscope Tip Stabilization and Complete Visualization and Dissection of Serrated Sessile Polyps |
MULVIHILL, MAUREEN L. |
NIDDK |
BELLEFONTE |
PA |
31-August-2025 |
| RIVANNA MEDICAL, INC. |
Commercialization readiness for a 3D image guidance system to support interventional procedures in the spine and pelvis |
MAULDIN, FRANK WILLIAM |
NIAMS |
CHARLOTTESVILLE |
VA |
31-August-2025 |
| STINGINN, LLC |
STING Activators as Therapy for Cancer |
BARBER, GLEN N |
NCI |
MIAMI |
FL |
31-August-2025 |
| MODENDO INC. |
Multi-probe minimally invasive endomicroscope |
CARAVACA AGUIRRE, ANTONIO MIGUEL |
NINDS |
BOULDER |
CO |
31-August-2025 |
| DOXY.ME, LLC |
Developing a virtual reality clinic to enhance telemental health. |
ONG, TRITON |
NIMH |
ROCHESTER |
NY |
31-August-2025 |
| F SQUARE MEDICAL LLC |
Development of the First-ever Safe and Effective Anterior Chamber Paracentesis Instrument to Treat and Diagnose Ocular Diseases |
FARAH, SAMER |
NEI |
TEANECK |
NJ |
31-August-2025 |
| DORIAN THERAPEUTICS, INC. |
Small molecule targeting an epigenetic regulator for the treatment of osteoarthritis |
ADORNO, MADDALENA |
NIA |
SAN CARLOS |
CA |
31-August-2025 |
| MODULO BIO, INC. |
Implementing a coupled system of integrative ML modeling and data validation for elucidating microglial therapeutic targets in neurodegenerative disease |
SACHS, KAREN |
NIMH |
San Diego |
CA |
31-August-2025 |
| RAFT PHARMACEUTICALS, LLC |
Targeting TLR4-lipid rafts to prevent postoperative pain |
DOUGHERTY, PATRICK M |
NINDS |
SAN DIEGO |
CA |
31-August-2025 |
| INSIGHT SURGICAL TECHNOLOGIES, LLC |
Wide-Field Quantitative Fluorescence Imaging System |
ROBERTS, DAVID W |
NCI |
LYME |
NH |
31-August-2025 |
| PINNACLE TECHNOLOGY, INC |
Commercialization of Enzyme Modified Carbon-Fiber Electrodes Paired with Voltammetry for Simultaneous Real-Time Monitoring of Electroactive and Non-Electroactive Species at Discrete Brain Locations |
JOHNSON, DAVID A |
NIMH |
LAWRENCE |
KS |
31-August-2025 |
| TEEN HEALTH RESEARCH, INC. |
Improving parent-adolescent communication about sexual and reproductive health |
WIDMAN, LAURA M. |
NICHD |
RALEIGH |
NC |
31-August-2025 |
| ARTIAM BIO INC. |
THERAPY FOR ALCOHOL USE DISORDER |
SELTZMAN, HERBERT H |
NIAAA |
CARY |
NC |
31-August-2025 |
| CALLA HEALTH FOUNDATION |
Optimizing ablation of cervical precancer with ethyl cellulose ethanol to enable translation to women in low and middle-income countries |
CROUCH, BRIAN |
NCI |
DURHAM |
NC |
31-August-2025 |
| ATLASXOMICS INC. |
A democratized platform for mapping the spatial epigenome in tissue |
SABINA, JEFFREY |
NCI |
NEW HAVEN |
CT |
31-August-2025 |
| D BIOTHERAPEUTICS, LLC |
A Potent D-peptide Inhibitor of TNFα for Treatment of Rheumatoid Arthritis |
RISDON, GRANT H |
NIAMS |
SALT LAKE CITY |
UT |
31-August-2025 |
| DERMAXON, LLC |
Selective CYP26 inhibitors for the oral treatment of recalcitrant nodular acne. |
DIAZ, PHILIPPE J |
NIAMS |
MISSOULA |
MT |
31-August-2025 |
| NEPHROPATHOLOGY ASSOCIATES |
A proprietary digital platform for precision patient identification and enrollment of clinical trials for rare kidney diseases |
LARSEN, CHRISTOPHER P |
NIDDK |
LITTLE ROCK |
AR |
31-August-2025 |
| WINDOW THERAPEUTICS, INC. |
Proteasome Inhibitor-Loaded Antibody Drug Conjugates with High Drug Loading For Targeted Treatment of Triple Negative Breast Cancers |
JIANG, YIVAN |
NCI |
Dorchester |
MA |
31-August-2025 |
| MOMEASE SOLUTIONS, INC. |
Novel warming and massaging bra for improved breast milk expression |
ASHLEY, MOONEYHAM |
NICHD |
PLYMOUTH |
MN |
31-August-2025 |
| SERPLUS TECHNOLOGY, LLC |
Enhanced pancreatic islet cell engraftment by treatment with serpin B1 |
PEMBERTON, PHILIP |
NIDDK |
SAN MATEO |
CA |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Automated Long-Term Oxygen Therapy Control System |
RYDBERG, NICK |
NHLBI |
SAINT PAUL |
MN |
31-August-2025 |
| STEM PHARM, INC. |
Human Neural Organoid Modeling of Alzheimer's Disease Neuroinflammation for Drug Discovery |
LEBAKKEN, CONNIE S |
NIA |
MADISON |
WI |
31-August-2025 |
| ARTEMIS BIOTECHNOLOGIES LLC |
Novel Pharmacological Treatment for Preeclampsia |
UDDIN, MOHAMMAD NASIR |
NICHD |
TEMPLE |
TX |
31-August-2025 |
| VANISH THERAPEUTICS INC. |
Opioid-Sparing Non-Surgical, Bioresorbable Nerve Stimulator for Pain Relief |
CUI, XINYAN TRACY |
NINDS |
MARS |
PA |
31-August-2025 |
| POPNEURON LLC |
Live spike sorting for multichannel and high-channel recordings |
LEI, TIM CHIFONG |
NINDS |
DENVER |
CO |
31-August-2025 |
| MC1R VENTURES LLC |
Vitiligo topical treatment applying a potent, highly selective MC1R agonist |
ABDEL-MALEK, ZALFA |
NIAMS |
CINCINNATI |
OH |
31-August-2025 |
| CENTER MOM, INC. |
Making Mindfulness-Based Cognitive Therapy accessible for underserved pregnant people: Developing Center M for commercialization |
TILDEN, ELLEN LANE |
NIMH |
PORTLAND |
OR |
31-August-2025 |
| H3PELVIC THERAPY SYSTEMS, INC. |
Targeted Temperature Modulation with Smart Radiometric Monitoring for Effective and Long-Lasting Opioid-Free Pelvic Pain Relief - A Novel Low-Cost, Portable, Tampon-sized Thermal Transfer Device. |
LYON, ZACHARY W |
NICHD |
LEWISVILLE |
NC |
31-August-2025 |
| KOBUK TECHNOLOGIES LLC |
Virtual Reality Technologies for Dynamic Balance Rehabilitation in People with Stroke |
SCHMIT, BRIAN D |
NICHD |
LAKE GENEVA |
WI |
31-August-2025 |
| NIGHTHAWK BIOSCIENCES, INC. |
An IGF-1R-targeting peptide drug conjugate for targeted treatment of atypical teratoid/rhabdoid tumors |
GOLDSTEIN, NEIL |
NCI |
Morrisville |
NC |
31-August-2025 |
| CREEGH PHARMACEUTICALS, INC. |
Synergize a novel homologous recombination inhibitor with DNA damagingagents in TNBC |
NEUMANN, CAROLA ANKE |
NCI |
PITTSBURGH |
PA |
31-August-2025 |
| SUS CLINICALS, INC. |
Validation of the Genetically Malleable Oncopig Hepatocellular carcinoma (HCC) Model for Targeted Therapeutic Development |
SCHACHTSCHNEIDER, KYLE |
NCI |
CINCINNATI |
OH |
31-August-2025 |
| SHASQI, INC. |
Antibody-guided localized activation of bioorthogonal protodrugs via click chemistry |
MEJIA ONETO, JOSE M |
NCI |
SAN FRANCISCO |
CA |
31-August-2025 |
| QENTOROS, LLC |
A novel therapeutic for the treatment of biofilms in periprosthetic joint infections |
GILBERTIE, JESSICA |
NIAID |
BLACKSBURG |
VA |
31-August-2025 |
| COLLABORATIONS PHARMACEUTICALS, INC. |
Preclinical development of a Nipah Virus inhibitor |
EKINS, SEAN |
NIAID |
FUQUAY VARINA |
NC |
31-August-2025 |
| SANARIA, INC. |
Modularizing manufacture of PfSPZ vaccines: ookinete production for PfSPZ manufacture in mosquitoes and in vitro |
HOFFMAN, STEPHEN LEV |
NIAID |
ROCKVILLE |
MD |
31-August-2025 |
| RIDGELINE THERAPEUTICS, LLC |
A Novel Small Molecule Oral Therapeutic to Prevent and Reverse Skeletal Muscle Atrophy in Aging Adults |
WILEY, ANDREA LEAH |
NIA |
Houston |
TX |
31-August-2025 |
| FLUIDITY SOFTWARE, INC. |
MTG: Math Team Games |
CARNEY, DONALD P |
NIGMS |
SOMERVILLE |
MA |
31-August-2025 |
| QUASAR, INC. |
A Dry Electrode for Universal Accessibility to EEG |
SOUSSOU, WALID |
NINDS |
San Diego |
CA |
31-August-2025 |
| SIGT, LLC |
Intraoperative Pulsed Field Ablation and Lesion Assessment System |
KARMARKAR, PARAG |
NHLBI |
COLUMBIA |
MD |
31-August-2025 |
| AEGISCN, LLC |
CN-105 Improves Functional Outcome After Intracranial Hemorrhage |
BENNETT, ELLEN |
NINDS |
DURHAM |
NC |
31-August-2025 |
| ADVAITA CORPORATION |
A web-based platform for robust single-cell analysis, bulk data deconvolution and system-level analysis |
IOSEF, CRISTIANA |
NIGMS |
ANN ARBOR |
MI |
31-August-2025 |
| GEL4MED, INC. |
Antimicrobial dermal matrices to promote infection free wound closure in DTU-DFUs. |
MEHTA, MANAV |
NIDDK |
BRIGHTON |
MA |
31-August-2025 |
| STEMSYNERGY THERAPEUTICS, INC. |
Small Molecule MYC Degraders as Novel Cancer Therapeutic Agents |
FEI, DENNIS LIANG |
NCI |
MIAMI |
FL |
31-August-2025 |
| CARI HEALTH, INC. |
Therapeutic Monitoring System (TMS) |
SCHMIDLE, PATRIK |
NIDA |
SAN DIEGO |
CA |
31-August-2025 |
| NEUROTYPE INC. |
Cue-induced drug craving monitoring for opioid use disorder with visual evoked potentials |
BURWELL, SCOTT |
NIDA |
MINNEAPOLIS |
MN |
31-August-2025 |
| GREENSTONE BIOSCIENCES, INC. |
Ethnically Diverse iPSC-Cardiomyocyte Panel for Pharmacogenomics and Drug Safety Testing |
AHMED, SYED MUKHTAR |
NHLBI |
PALO ALTO |
CA |
31-August-2025 |
| GLYCAN THERAPEUTICS CORPORATION |
Sulfated Carbohydrates for the Treatment of Periodontitis |
MIGUEZ, PATRICIA |
NIDCR |
Raleigh |
NC |
31-August-2025 |
| BIOSURFACES |
Implantable Electrospun Cell Chamber Device with Immune-Evasive Properties for Beta Cell Replacement Therapy |
HAYDEN, PATRICK J |
NIDDK |
ASHLAND |
MA |
31-August-2025 |
| NAPROGENIX, INC |
Mimicking synuclein toxicity in plant cells to identify novel neuroprotective leads |
HUANG, CHIFU |
NINDS |
LEXINGTON |
KY |
31-August-2025 |
| METCURE THERAPEUTICS, LLC |
Small-molecule therapy for metastatic castration-resistant prostate cancer |
WU, DAQING |
NCI |
ATLANTA |
GA |
31-August-2025 |
| PRECISION MICROWAVE, INC. |
MWA verification system for improved confidence in treatment outcomes |
PFANNENSTIEL, AUSTIN |
NCI |
MANHATTAN |
KS |
31-August-2025 |
| DUPAGE MEDICAL TECHNOLOGY, INC. |
Developing a new drug for treating myocardial ischemia/reperfusion injury |
SKIDGEL, RANDAL A |
NHLBI |
Chicago |
IL |
31-August-2025 |
| DIVINER THERAPEUTICS, LLC |
Targeting cadherin-11 in pancreatic cancer |
DAKSHANAMURTHY, SIVANESAN |
NCI |
FAIRFAX |
VA |
31-August-2025 |
| GRADIENT MEDICAL, INC. |
Feasibility of a Multi-Phase Algorithmic Non-Thermal Ablation Technology for the Treatment of Inoperable Tumors |
FONG, JORDAN |
NCI |
CARY |
NC |
31-August-2025 |
| PERIKINETICS INC |
An Intraperitoneal Insulin Delivery System for Management of Type 1 Diabetes |
HANSON, CHRISTOPHER |
NIDDK |
DALLAS |
TX |
31-August-2025 |
| FRAMESHIFT LABS, INC. |
A state-of-the-art web platform for collaborative, longitudinal genome diagnostics |
WARD, ALISTAIR |
NHGRI |
CAMBRIDGE |
MA |
31-August-2025 |
| NEWVENTUREIQ, LLC |
Clinical biomarker for early prediction of chemotherapy-induced peripheral neuropathy |
HAROUTOUNIAN, SIMON |
NCI |
St. Louis |
MO |
31-August-2025 |
| GATEWAY BIOTECHNOLOGY, INC. |
Developing a clinical diagnostic tool for age-related cochlear synaptopathy. |
PINKL, JOSEPH |
NIA |
St. Louis |
MO |
31-August-2025 |
| IMPACTIV, INC. |
Improving physical function and quality of life in older adults with prediabetes utilizing interactive small-group resistance training through video conference technology |
LEVITAN, ERIC |
NIA |
ATLANTA |
GA |
31-August-2025 |
| CLEARNANO, INC. |
Advancing Fluorescence Imaging-guided Partial Nephrectomy with ClearICG |
YU, MENGXIAO |
NCI |
PLANO |
TX |
31-August-2025 |
| NOVOBIOTIC PHARMACEUTICALS, LLC |
Teixobactin Development for Tuberculosis |
HUGHES, DALLAS |
NIAID |
CAMBRIDGE |
MA |
31-August-2025 |
| KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT |
Care Assistant for Family Caregivers of Persons with Dementia During Out of the Home Activities |
ANDERSON, SHANE M. |
NIA |
Minneapolis |
MN |
31-August-2025 |
| HOPEFUL AGING LLC |
Making Connections Thru Music: A Group Music Therapy-Based Intervention for Persons with Dementia |
GORZELLE, GREGG |
NIA |
WINCHESTER |
MA |
31-August-2025 |
| PHOENIX NEST, INC. |
Evaluation of Clinical Outcome Assessment (COA) and Potential Biomarkers to Facilitate Interventional Trial for Mucopolysaccharidosis IIID Patients |
SINGAMSETTY, SRIKANTH |
NINDS |
BROOKLYN |
NY |
31-August-2025 |
| EMITECH, INC. |
Wearable sensor for opioids detection based on electrochemical sensor arrayintegrated with Bluetooth device |
LEVITSKY, IGOR A |
NIDA |
FALL RIVER |
MA |
31-August-2025 |
| XLOCK BIOSCIENCES, LLC |
Targeting the CCR6-CCL20 pathway for treatment of psoriatic joint and entheseal inflammation |
CLARKE, WILLIAM R |
NIAMS |
MUSKEGO |
WI |
31-August-2025 |
| RISE THERAPEUTICS, LLC |
R-5280, A Novel Modified Superior Resistant Starch Therapy for Type 1 Diabetes |
FURLAN FREGUIA, CHRISTIAN |
NIDDK |
Rockville |
MD |
31-August-2025 |
| MINDTRACE TECHNOLOGIES, INC. |
Development of an innovative neurosurgical planning tool for awake craniotomy |
SIMS, MAXWELL HARRISON |
NIMH |
PITTSBURGH |
PA |
31-August-2025 |
| FESARIUSTHERAPEUTICS, INC. |
DermiSphere™: An Advanced Dermal Regeneration Scaffold for Reconstructive Surgery, CRP |
SAPIR LEKHOVITSER, YULIA |
NIAMS |
NEW YORK |
NY |
31-August-2025 |
| BIOSENSICS, LLC |
Software Platform for Automatic, Opportunistic Screening of Vertebral Compression Fractures |
VAZIRI, ASHKAN |
NIA |
Newton |
MA |
31-August-2025 |
| CND LIFE SCIENCES, INC. |
Cutaneous Phosphorylated Alpha-Synuclein for Detection of Prodromal Synucleinopathies |
LEVINE, TODD |
NINDS |
Scottsdale |
AZ |
31-August-2025 |
| PROTEINACEOUS, INC. |
Data-Driven Software to Automate Top-Down Mass Spectrometry of Large Molecules |
DURBIN, KENNETH |
NIGMS |
EVANSTON |
IL |
31-August-2025 |
| VIRTUALLY BETTER, INC. |
Disseminable Evidence-Based Treatment for the Dental Office: Virtual Exposure Tools for Dental Fear - neVR Fear the Dentist |
ADAMS LARSEN, MARGO |
NIDCR |
DECATUR |
GA |
31-August-2025 |
| BACKYARD BRAINS, INC. |
Introducing Neuroscience and Neurocomputation Concepts to High School Students using Brain-based Neurorobots |
GAGE, GREGORY JOHN |
NINDS |
ANN ARBOR |
MI |
31-August-2025 |
| GLYCOMANTRA, INC. |
Targeting galectin-3 to overcome insulin resistance in type 2 diabetes |
AHMED, HAFIZ |
NIDDK |
LEESBURG |
VA |
31-August-2025 |
| SERENTRIX, LLC |
Validating SER-014, a TRPV1 antagonist, to treat endometriosis |
BHARGAVA, KUMARIL |
NICHD |
EXTON |
PA |
31-August-2025 |
| GLYCOMIRA, LLC |
Development of a Diagnostic Test for Eosinophilic Chronic Rhinosinusitis |
PULSIPHER, ABIGAIL |
NIAID |
SALT LAKE CITY |
UT |
31-August-2025 |
| 3P BIOTECHNOLOGIES, INC. |
Targeted Exosomal Delivery of siRNA Therapeutics for Neuroinflammatory Diseases |
GUPTA, RAMESH C |
NIA |
PROSPECT |
KY |
31-August-2025 |
| BIOSENSICS, LLC |
StrokeWear: A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Home Daily Life. |
VAZIRI, ASHKAN |
NICHD |
Newton |
MA |
31-August-2025 |
| GEL4MED, INC. |
Antimicrobial dermal matrices to promote infection free wound closure in DTU-DFUs. |
MEHTA, MANAV |
NIDDK |
BRIGHTON |
MA |
31-August-2025 |
| DOLOR THERAPEUTICS, LLC |
Optimizing Dual Therapy for Chronic Prostatitis/Chronic Pelvic Pain Syndrome |
SARGENT, WILLIAM Q |
NIDDK |
CHICAGO |
IL |
31-August-2025 |
| PRE-CANCER DIAGNOSIS, LLC |
Development of a highly sensitive DNA hypermethylation-based kit to identify Barrett's esophagus patients at high risk of progressing to esophageal adenocarcinoma |
ZHOU, ZHONGREN |
NCI |
BELLE MEAD |
NJ |
31-August-2025 |
| O2M TECHNOLOGIES, LLC |
Multifunctional EPRI Instrument to Advance Therapies in Biomedical Sciences |
KOTECHA, MRIGNAYANI |
NCI |
CHICAGO |
IL |
31-August-2025 |
| CHEMIA BIOSCIENCES, INC. |
Discovering novel natural products from fungal species |
BEHSAZ, BAHAR |
NIGMS |
PITTSBURGH |
PA |
31-August-2025 |
| IMETABOLIC BIOPHARMA CORPORATION |
Therapeutic Approach to Clear sdLDL from Circulation |
KIERNAN, URBAN A |
NHLBI |
TEMPE |
AZ |
31-August-2025 |
| UP ONCOLYTICS, INC. |
Validation of a novel treatment for glioblastoma using oncolytic Zika virus |
AKHTAR, PARVEZ |
NINDS |
MILWAUKEE |
WI |
31-August-2025 |
| SKYWAY BIOSCIENCES |
Optimization and Validation of Minimally-Invasive and Low-Cost Blood Collection Device for Lead Testing |
AHUJA, PUNKAJ |
NIEHS |
EVANSTON |
IL |
31-August-2025 |
| BOLD TYPE LLC |
An intravaginal, wearable device for treating women with pelvic floor myofascial pain |
BOHORQUEZ, JOSE LUIS |
NICHD |
ORLANDO |
FL |
31-August-2025 |
| ABLELINK SMART LIVING TECHNOLOGIES LLC |
Development and Evaluation of Technology and Safety Supports for Individuals with Intellectual and Developmental Disabilities to Independently Use Driverless and Driver Supported Ridehailing Services |
DAVIES, DANIEL K |
NICHD |
COLORADO SPRINGS |
CO |
31-August-2025 |
| GALATEA BIO INC |
Development and application of machine learning-based approaches for estimating disease risk in diverse and admixed populations. |
WALL, JEFFREY D |
NHGRI |
HIALEAH |
FL |
31-August-2025 |
| THER-AI LLC |
iLIGN - Artificial Intelligence Driven Strabismus Pre-Screening System |
SHAIKH, SAAD |
NEI |
Kissimmee |
FL |
31-August-2025 |
| LUMINARY THERAPEUTICS, INC. |
An allogeneic gamma/delta armored Dual-Targeting CAR with Split Costimulatory Domains to Target Epithelial Ovarian Carcinoma |
LEWIS, ANDREW KYLE |
NCI |
MINNEAPOLIS |
MN |
31-August-2025 |
| AXONIS THERAPEUTICS, INC. |
Development of Oral KCC2 Potentiator AXN-027 as a Novel Anti-Epileptic Drug for Mesial Temporal Lobe Epilepsy |
KADAM, SHILPA DATTATRAY |
NINDS |
BOSTON |
MA |
31-August-2025 |
| REBEL MEDICINE INC |
Extending duration of an injectable long-acting local anesthetic formulation using novel salts |
DAVIS, BRETT |
NIDA |
Salt Lake City |
UT |
31-August-2025 |
| SYNTRIX BIOSYSTEMS, INC. |
A Dose Expansion Study of SX-682 Alone and in Combination with Decitabine in MDS Patients |
SCHULER, AARON D |
NCI |
AUBURN |
WA |
31-August-2025 |
| NORTHWEST PREVENTION SCIENCE INC |
Cultural Adaptation of Family Check-Up to Reduce Health Disparities and Improve MentalHealth among Hispanic Families |
REITER, LISA ANN |
NIMHD |
EUGENE |
OR |
31-August-2025 |
| EQUITI FOODS, LLC |
Achieving health equity through food as medicine and medically tailored meals: local economic opportunity |
AMMERMAN, ALICE S |
NIMHD |
CHAPEL HILL |
NC |
31-August-2025 |
| ACTOPROBE, LLC |
Novel Optical Scanning Probe Microscope for Biomedical Chemical Imaging with Ultra-High Spatial Resolution and Chemical Sensitivity |
UKHANOV, ALEXANDER A |
NIBIB |
ALBUQUERQUE |
NM |
31-August-2025 |
| SANARIA, INC. |
Modularizing manufacture of PfSPZ vaccines: ookinete production for PfSPZ manufacture in mosquitoes and in vitro |
HOFFMAN, STEPHEN LEV |
NIAID |
ROCKVILLE |
MD |
31-August-2025 |
| GENERAL BIOPHYSICS, LLC |
Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects |
ILIN, ILYA |
NIA |
WAYLAND |
MA |
31-August-2025 |
| AFASCI, INC. |
Clinical Phase I trials on an IND single molecule dual inhibitor of Cav3 channels and soluble epoxide hydrolase for treatment of neuropathic pain |
XIE, XINMIN SIMON |
NINDS |
REDWOOD CITY |
CA |
31-August-2025 |
| QENTOROS, LLC |
A novel therapeutic for the treatment of biofilms in periprosthetic joint infections |
GILBERTIE, JESSICA |
NIAID |
BLACKSBURG |
VA |
31-August-2025 |
| SANAHEAL, INC. |
Strain-Programmed Bioadhesive Patch for Enhanced Diabetic Wound Healing |
YUK, HYUNWOO |
NIDDK |
Cambridge |
MA |
31-August-2025 |
| QUADRIDOX, INC. |
Development and evaluation of a combined X-ray transmission and diffraction imaging system for pathology |
GREENBERG, JOEL |
NIBIB |
DURHAM |
NC |
31-August-2025 |
| VIRTUOSO SURGICAL, INC. |
A Robotic System to Remove Bladder Tumors Intact: The Key to Making Lifesaving Treatment Decisions |
HENDRICK, RICHARD JOSEPH |
NIBIB |
NASHVILLE |
TN |
31-August-2025 |
| RADIATION MONITORING DEVICES, INC. |
Semiconductor detector for low-dose, high-resolution dental DR imaging |
CHRISTIAN, JAMES F |
NIDCR |
WATERTOWN |
MA |
31-August-2025 |
| KLEIN BUENDEL, INC. |
An Interactive Education Program to Reduce High Risk Behavior in Adolescents |
HOUCK, CHRISTOPHER D. |
NICHD |
GOLDEN |
CO |
31-August-2025 |
| VIRTUS THERAPEUTICS CORPORATION |
PANK Activators for the treatment of pantothenate kinase-associated neurodegeneration |
REGAN, JESSICA |
NINDS |
Groton |
CT |
31-August-2025 |
| MINNESOTA HEALTHSOLUTIONS CORPORATION |
Automated Long-Term Oxygen Therapy Control System |
RYDBERG, NICK |
NHLBI |
SAINT PAUL |
MN |
31-August-2025 |
| LUCIOLE PHARMACEUTICALS, INC. |
Discovery and development of OGG1 activators as precision drugs for modification of Alzheimer's disease progression. |
RUMSEY, WILLIAM L |
NIA |
Sherborn |
MA |
31-August-2025 |
| MODULO BIO, INC. |
Implementing a coupled system of integrative ML modeling and data validation for elucidating microglial therapeutic targets in neurodegenerative disease |
SACHS, KAREN |
NIMH |
San Diego |
CA |
31-August-2025 |
| FLUIDITY SOFTWARE, INC. |
MTG: Math Team Games |
CARNEY, DONALD P |
NIGMS |
SOMERVILLE |
MA |
31-August-2025 |
| SILOAM VISION, INC. |
Validation of artificial intelligence (AI) based software as medical device (SaMD) for retinopathy of prematurity (ROP) |
JONAS, KARYN |
NEI |
LAKE OSWEGO |
OR |
31-August-2025 |
| 7 HILLS PHARMA, LLC |
7HP349, an Integrin Activator to Treat Patients With anti-PD-1 Resistant Solid Tumors |
MARATHI, UPENDRA |
NCI |
HOUSTON |
TX |
31-August-2025 |
| LIBERATING TECHNOLOGIES, INC. |
The Development of a Bimodal Walking-Running Prosthetic Foot |
JOHANSSON, JENNIFER LYNNE |
NICHD |
HOLLISTON |
MA |
31-August-2025 |
| ATLASXOMICS INC. |
A democratized platform for mapping the spatial epigenome in tissue |
SABINA, JEFFREY |
NCI |
NEW HAVEN |
CT |
31-August-2025 |
| PHARMAIN CORPORATION |
Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and human |
ALFARO, JOSHUA |
NCI |
BOTHELL |
WA |
31-August-2025 |
| VINCERE BIOSCIENCES, INC. |
In vivo Evaluation of USP30 Inhibitors in Models Relevant to Parkinson's Disease |
BEHROUZ, BAHAREH |
NINDS |
Cambridge |
MA |
31-August-2025 |
| DIOPTER TECHNOLOGIES, INC. |
Sustained cysteamine delivery by nanobarrier contact lenses to replace 8xdaily drops with a daily disposable lens |
ADAMS, CHRIS |
NEI |
SOMERVILLE |
MA |
31-August-2025 |
| BIOLOGICAL MIMETICS, INC. |
Development of a Staph Aureus Vaccine |
DOLLERY, STEPHEN JEFFREY |
NIAID |
FREDERICK |
MD |
31-August-2025 |
| ANELLEO, INC. |
Innovative 3D Printed Intravaginal Ring AnelleO-PRO, the first Single Administration of Progesterone for Infertility |
JANUSZIEWICZ, RIMA |
NICHD |
CHAPEL HILL |
NC |
31-August-2025 |
| AUTONOMOUS HEALTHCARE, INC. |
Using Machine Learning and Blockchain Technology to Reduce Drug Diversion in Hospitals |
GHOLAMI, BEHNOOD |
NIDA |
Santa Clara |
CA |
31-August-2025 |
| CAMINO PHARMA, LLC |
Preclinical validation of mGlu2 PAMs in alcohol use disorder |
GADIENT, RETO ANDREAS |
NIAAA |
SAN DIEGO |
CA |
31-August-2025 |
| STEMSYNERGY THERAPEUTICS, INC. |
Small Molecule MYC Degraders as Novel Cancer Therapeutic Agents |
FEI, DENNIS LIANG |
NCI |
MIAMI |
FL |
31-August-2025 |
| NASONI LLC |
Access-H20: Sensor driven smart faucet to enable and empower independent drinking and grooming for individuals impacted by spinal cord injury |
WADDELL, JOHN STEVEN |
NICHD |
SUFFOLK |
VA |
31-August-2025 |
| AEGISCN, LLC |
CN-105 Improves Functional Outcome After Intracranial Hemorrhage |
BENNETT, ELLEN |
NINDS |
DURHAM |
NC |
31-August-2025 |
| IMMUNOBLUE, LLC |
Engineered Glioblastoma-specific T cells using Immunostimulatory Photothermal Nanoparticles |
SWEENEY, ELIZABETH E |
NCI |
BETHESDA |
MD |
31-August-2025 |
| FORESIGHTCARES INC. |
AVA_ AI Video-Based Mobile Application for Reliable, Accessible, and Low-Cost Fall Risk Assessments of Older Adults |
TABKHI, HAMED |
NIA |
MATTHEWS |
NC |
31-August-2025 |
| FESARIUSTHERAPEUTICS, INC. |
An advanced dermal regeneration scaffold for skin loss due to burn wounds |
SAPIR LEKHOVITSER, YULIA |
NIGMS |
NEW YORK |
NY |
31-August-2025 |
| SYNTIS BIO INC |
Development of an Oral Pill to Mimic the Effects of Gastric Bypass Surgery |
YU, ANTHONY |
NIDDK |
Boston |
MA |
31-August-2025 |
| BARRON ASSOCIATES, INC. |
A system to enhance prevention of diabetic foot ulcers and their recurrence |
CLARK, BRIAN R |
NIDDK |
CHARLOTTESVILLE |
VA |
31-August-2025 |
| MIRA MEDICAL, LLC |
AI Enabled App for Fracture Reduction Prediction in Pediatrics |
CLEARY, KEVIN R. |
NIAMS |
POTOMAC |
MD |
31-August-2025 |
| ELECTRONIC BIOSCIENCES, INC. |
Fourth-Generation Nanopore-Assisted Sequencing for Advanced Oncological Analyses |
PETERSON, ERIC MAYO |
NCI |
SAN DIEGO |
CA |
31-August-2025 |
| ADAPTIVE TESTING TECHNOLOGIES |
Development and Validation of a Computerized Adaptive Test of Fatigability |
COHEN, YEHUDA |
NIA |
CHICAGO |
IL |
31-August-2025 |
| MATERIALS NOVA LIMITED LIABILITY COMPANY |
Innovative Point-of-Use Water Purification System: Portable, Scalable, Efficient, Easy-Use |
LI, HUIFENG |
NIEHS |
AUSTIN |
TX |
31-August-2025 |
| STARLIGHT CARDIOVASCULAR, INC. |
Commercialization Readiness for Ductus Arteriosus Stent to Improve Congenital Heart Defect Mortality |
TANG, BEVERLY |
NHLBI |
San Diego |
CA |
31-August-2025 |
| ONCOBLAZE LLC |
Laser-guided drug delivery to prevent tumor recurrences |
HAEMMERICH, DIETER |
NIBIB |
CHARLESTON |
SC |
31-August-2025 |
| ORA BIOMEDICAL, INC. |
EleGantry: a software and hardware infrastructure to improve rigor and reproducibility within invertebrate research |
LEE, MITCHELL BRENDON |
OD |
TUKWILA |
WA |
31-August-2025 |
| CREATIVE BIOTHERAPEUTICS, LLC |
Developing a Novel Biologic Therapy to Eradicate Brain Cancer and Brain Metastasis |
DAVIDSON, DONALD |
NCI |
GURNEE |
IL |
31-August-2025 |
| PENDAR TECHNOLOGIES, LLC |
Monitoring of Oxygen Delivery and Tissue Oxygenation Deprivation in Critically Ill Neonates Using Resonance Raman Spectroscopy |
VAKHSHOORI, DARYOOSH |
NICHD |
CAMBRIDGE |
MA |
31-August-2025 |
| RECOMBINETICS, INC. |
Gene Therapy for MPS IV A in a Novel Porcine Model of the Disease |
CAMPBELL, JARRYD MATTHEW |
NIAMS |
Eagan |
MN |
31-August-2025 |
| EVIMERO, LLC |
Targeted Immunotherapeutics In Dysbiotic Microbiomes - A Feasibility and Proof-of-Concept Study |
GOEPP, JULIUS G |
NCATS |
TUSCALOOSA |
AL |
31-August-2025 |
| INTEGURX THERAPEUTICS LLC |
Development of an Ondansetron Transdermal Patch for Pregnancy-Induced Nausea and Vomiting |
SHANGOLD, GARY |
NICHD |
CALIFON |
NJ |
31-August-2025 |
| CEIBA BIO INC. |
Developing blood-based exercise mimetic as a treatment for Alzheimer's disease and related dementias |
DING, ZHAOQING |
NIA |
SAN DIEGO |
CA |
31-August-2025 |
| XYLYX BIO, INC. |
Liver fibrosis cell-based assay platform: integrating patient-derived fibrotic liver ECM with primary stellate cells, Kupffer cells, and hepatocytes to accelerate anti-fibrotic drug development |
O'NEILL, JOHN DAVID |
NIDDK |
BROOKLYN |
NY |
31-August-2025 |
| RENERVA, LLC |
Restoration of Neuromuscular Function Following Critical Nerve Gap Injuries |
SOLETTI, LORENZO |
NINDS |
PITTSBURGH |
PA |
31-August-2025 |
| ASSISTIVE TECHNOLOGY DEVELOPMENT, INC. |
A lightweight robotic telerehabilitation device with integrated blood flow restriction for patients with musculoskeletal conditions |
WILKINSON, DAVID |
NIBIB |
TIMNATH |
CO |
31-August-2025 |
| AMISSA, INC. |
Augmented Preclinical Alzheimer's Disease Detection Through Wearable Health and Driving Behavior Data. |
FORD, COLBY T. |
NIA |
Charlotte |
NC |
31-August-2025 |
| SPOTTED TECH LLC |
CD4-LINK: Improving access to HIV care in underserves areas with a home-based, mail-in CD4 count test |
FAHLBERG, MARISSA |
NIMH |
NEW ORLEANS |
LA |
31-August-2025 |
| KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT |
Interactive Gaming Platform to Facilitate Cognitive Interventions for Dementia |
RIEHLE, TIMOTHY H. |
NIA |
Minneapolis |
MN |
31-August-2025 |
| SHASQI, INC. |
Antibody-guided localized activation of bioorthogonal protodrugs via click chemistry |
MEJIA ONETO, JOSE M |
NCI |
SAN FRANCISCO |
CA |
31-August-2025 |
| LABSYS, LLC |
Wearable Continuous Drug Monitoring Device for Personal Medications in Opioid Use Disorders (CDM-MOUD) |
HUANG, YUE |
NIDA |
EAST LANSING |
MI |
31-August-2025 |
| PACDNA LLC |
Molecular brush-conjugated antisense oligonucleotide as a pan-KRAS depletion agent |
ZHANG, KE |
NCI |
NATICK |
MA |
31-August-2025 |
| ENZYME BY DESIGN, INC. |
A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy |
SCHALK, AMANDA M |
NCI |
CHICAGO |
IL |
31-August-2025 |
| LARIX BIOSCIENCE, LLC |
Advancing a novel therapy for preeclampsia |
YU, BO |
NICHD |
SUNNYVALE |
CA |
31-August-2025 |
| VIBRATO MEDICAL, INC. |
Non-invasive therapeutic ultrasound device for treatment of peripheral arterial disease in elderly population |
ELSTAD, JULIANA |
NIA |
NEWPORT COAST |
CA |
31-August-2025 |
| GINER, INC. |
Rapid, Multiplexed Biosensor for Non-Invasive Detection of Gene Mutations and Personalization of Therapy in Non-Small Cell Lung Cancer |
ARGUN, AVNI A |
NCI |
NEWTON |
MA |
31-August-2025 |
| BENTEN TECHNOLOGIES, INC. |
OC-DETECT,A mHealth for CHWs can facilitate the task-shifting of intake, provide on-demand training, improve communication between CHWs and their supervisors, and support digital-enhanced referral |
MA, TONY XUYEN |
NCI |
MANASSAS |
VA |
31-August-2025 |
| WAYPATH PHARMA LLC |
New anti-glioblastoma metabolic compounds with high potential for Blood Brain Barrier penetration |
REISS, KRZYSZTOF |
NCI |
METAIRIE |
LA |
31-August-2025 |
| CONQUERAB, INC. |
DISPOSABLE DEVICE FOR RAPID POINT-OF-CARE DETECTION AND COMPARISON OF ANTIBODY RESPONSES AGAINST THERAPEUTIC PROTEINS IN RHEUMATOID ARTHRITIS PATIENTS |
BARBOSA, MARIA D. F. S. |
NIAMS |
GAINESVILLE |
FL |
31-August-2025 |
| PRETEL, INC. |
Labor Status Monitor for diagnosing True versus False Labor in preterm patients |
YOUNG, ROGER C. |
NICHD |
Chattanooga |
TN |
31-August-2025 |
| NATGLYCAN, LLC |
A Human Salivary Glycome Discovery Platform for Interrogating Glycan Function in Oral Innate Immunity |
SMITH, DAVID FLETCHER |
NIDCR |
Tucker |
GA |
31-August-2025 |
| VISO THERAPEUTICS INC. |
Development of a Peptide Therapy for Corneal Wound Healing |
FLAVIN, MICHAEL |
NEI |
CHICAGO |
IL |
31-August-2025 |
| MIYAZAKI ENTERPRISES, LLC |
Effect of Validated Skills Simulation with the Miya Model on Operating Room Performance of Vaginal Hysterectomy |
MIYAZAKI, DOUGLAS W. |
NICHD |
WINSTON-SALEM |
NC |
31-August-2025 |
| VERAVANTI, INC. |
Endoscope development for the clinical use of near infrared fluorescence molecular probes in the GI tract |
MCMORROW, GERALD |
NCI |
REDMOND |
WA |
31-August-2025 |
| CHOSEN DIAGNOSTICS, INC. |
Noninvasive biomarkers for gastrointestinal disease in preterm infants |
BUCKLEY, REBECCA S |
NICHD |
NEW ORLEANS |
LA |
31-August-2025 |
| RISSANA, LLC |
A digital intervention to decrease self-stigma among pregnant and postpartum women with opioid use disorder |
GOODMAN, MICAH |
NIDA |
Saint Louis |
MO |
31-August-2025 |
| BENTEN TECHNOLOGIES, INC. |
PRECARE is an innovative and integrated platform designed to improve the developmental surveillance of the baby. |
MA, TONY XUYEN |
NICHD |
MANASSAS |
VA |
31-August-2025 |
| PILLTRAX SYSTEMS LLC |
Enhanced Medication Management to Control ADRD Risk Factors Among African Americans and Latinos |
RAMSEY, ALVIN |
NIA |
Brighton |
MA |
31-August-2025 |
| CELDARA MEDICAL, LLC |
Kv2.1-Targeted First in Class Neuroprotective Therapeutic for Acute Ischemic Stroke |
COLEMAN, JULIE H |
NINDS |
LEBANON |
NH |
31-August-2025 |
| TRESTLE OPTICS LLC |
Rapid and high-contrast photothermal microscopy with a novel tunable ZGP source |
HANNINEN, ADAM M |
NIGMS |
IRVINE |
CA |
31-August-2025 |
| N8 MEDICAL, INC. |
Ceragenin-based antimicrobial coating to tackle hemodialysis catheter-related infections. |
BRUNNER, GLENN |
NIDDK |
Dublin |
OH |
31-August-2025 |
| DAXOR CORPORATION |
Precision Guidance of Resuscitation and Deresuscitation in Sepsis |
FELDSCHUH, JONATHAN |
NIGMS |
OAK RIDGE |
TN |
31-August-2025 |
| LEAFLABS, LLC |
High channel count electrophysiology and data processing for freely-moving animals |
SHERWOOD, JOHN L |
NIMH |
CAMBRIDGE |
MA |
31-August-2025 |
| MYOSIN THERAPEUTICS INC. |
Development of a first-in-class nonmuscle myosin II inhibitor to prevent substance use disorder relapse |
YOUNG, ERICA J |
NIDA |
JUPITER |
FL |
31-August-2025 |
| MOAI TECHNOLOGIES, LLC |
Covering Care: Long-term care planning and education tool for AD/ADRD caregivers |
OLOFINBOBA, OLU |
NIA |
MAPLE GROVE |
MN |
31-August-2025 |
| ADVANCED MRI TECHNOLOGY, LLC |
Highly Efficient MRI Pulse Sequences for High Resolution Physiological and Functional Brain Imaging |
FEINBERG, DAVID ALAN |
NIMH |
SEBASTOPOL |
CA |
31-August-2025 |
| 4E THERAPEUTICS INC. |
Development and Optimization of MNK Inhibitors for the Treatment of Neuropathic Pain |
SAHN, JAMES JEFFREY |
NINDS |
AUSTIN |
TX |
31-August-2025 |
| APT THERAPEUTICS, INC. |
Immunomodulatory Therapy for Neuropathic Pain |
CHEN, RIDONG |
NINDS |
Naperville |
IL |
31-August-2025 |
| EPICYPHER, INC. |
Multiomic genomic mapping with long read sequencing |
BURG, JONATHAN MICHAEL |
NIGMS |
Research Triangle Park |
NC |
31-August-2025 |
| ADECTO PHARMACEUTICALS, INC. |
Development of a Companion Diagnostic Assay for Detection of ADAM8-Positive Cancers |
SONENSHEIN, GAIL E. |
NCI |
BROOKLINE |
MA |
31-August-2025 |
| TETRAIMAGING, LLC |
Novel tetrahedron beam CT for point-of-care imaging in ear, nose and throat imaging |
TOKER, EMRE |
NIBIB |
SAINT LOUIS |
MO |
31-August-2025 |
| RIVANNA MEDICAL, INC. |
Real-time three-dimensional spinal navigation system for bedside lumbar puncture placement |
MAULDIN, FRANK WILLIAM |
NINDS |
CHARLOTTESVILLE |
VA |
31-August-2025 |
| IFIT PROSTHETICS, LLC |
Adjustable prosthetic sockets for children and adolescents with lower limb loss to accommodate growth |
DILLINGHAM, TIMOTHY R |
NICHD |
PEWAUKEE |
WI |
31-August-2025 |
| QUANTITATIVE IMAGING SYSTEMS, LLC |
Ultra-high content analyses of circulating and solid tumor cells: A diagnostic reference system for disease burden |
NEDERLOF, MICHEL |
NCI |
MONROEVILLE |
PA |
31-August-2025 |
| WR BIOTECH, LLC |
Protection of transplanted heart function by regulation of Na/K pump activity |
LIU, RUISHENG |
NHLBI |
TAMPA |
FL |
31-August-2025 |
| CYTONUS THERAPEUTICS, INC. |
Development of CA-IL-12 for Triple Negative Breast Cancer |
FILARDO, EDWARD J |
NCI |
COLUMBUS |
OH |
31-August-2025 |
| FORTISCIENCE, INC. |
Development of a Small Molecule Inhibitor of Fortilin for Atherosclerosis Treatment and Prevention |
FUJISE, KEN |
NHLBI |
Dover |
DE |
31-August-2025 |
| SPRINGBOK, INC. |
Clinical evaluation of a commercially viable machine learning algorithm to automatically detect shoulder muscle pathology |
RIEM, LARA ISABELLA |
NIAMS |
Charlottesville |
VA |
31-August-2025 |
| BLUE IRIS LABS, INC. |
A light exposure tracker designed to improve the circadian entrainment for Alzheimer Disease patients |
PAGE, ERIK |
NIA |
FAIRFAX |
CA |
31-August-2025 |
| NEWOMICS, INC |
Picoelectrospray Ionization Mass Spectrometry for Top-down Proteomics |
WANG, DAOJING |
NIGMS |
Berkeley |
CA |
31-August-2025 |
| INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. |
Affordable sialoglycans and associated reagents for expanded chemoenzymatic production |
LEE, LIM ANDREW |
NIGMS |
IRMO |
SC |
31-August-2025 |
| CLARIA MEDICAL, INC. |
A Safe, Fast, and Cost-Effective System for Tissue Removal in Laparoscopic Hysterectomy and Other Minimally Invasive Surgery |
FRANCIS, DANIEL |
NICHD |
Mountain View |
CA |
31-August-2025 |
| EXQOR TECHNOLOGIES, INC. |
New BDNF Nanoparticles for Early Treatment of Alzheimer's Disease |
VITALIANO, FRANCO |
NIA |
BOSTON |
MA |
31-August-2025 |
| LUCERNA, INC. |
Fluorescent IRE sensor for synucleinopathy drug discovery |
SHEN, WEN |
NINDS |
Brooklyn |
NY |
31-August-2025 |
| TOTAL CHILD HEALTH, INC. |
Validation of the online Toddler Autism and Development Adaptive Screener (TADAS) at 18 months |
HOWARD, BARBARA JO |
NICHD |
BALTIMORE |
MD |
31-August-2025 |
| INFRATRAC, INC. |
Design and Engineering of Biodegradable 3D Nanoprinted Microcarriers for HIV Drug Delivery |
FLANK, SHARON |
NIAID |
SILVER SPRING |
MD |
31-August-2025 |
| GEN-9, INC. |
Auracle: An AI-Enabled Telecare System to Support the Independence and Safety of Individuals with AD/ADRD and Other Dementias |
FAUCI, MARK A |
NIA |
MOUNTAIN VIEW |
CA |
31-August-2025 |
| BIOTHERAPEUTICS, INC. |
Development of Novel Topical Therapeutics for Psoriasis |
TUBAU JUNI, NURIA |
NIAMS |
BLACKSBURG |
VA |
31-August-2025 |
| TINY CARGO COMPANY, THE |
Novel Drug Delivery Platform as Medical Countermeasure for treatment of Gastrointestinal Radiation Damage |
MARSH, SPENCER REID |
NCI |
ROANOKE |
VA |
31-August-2025 |
| COURAGE THERAPEUTICS, INC. |
Development of Novel Melanocortin-4 Receptor Peptide Agonists for the Treatment ofMC4R Haploinsufficiency |
SAWYER, TOMI K |
NIDDK |
NEWTON |
MA |
31-August-2025 |
| ADVAC THERAPEUTIC, LLC |
Targeted delivery of novel miRNA-based therapeutics for pneumonia-induced acute lung injury |
AKERLEY, BRIAN |
NIAID |
Phoenixville |
PA |
31-August-2025 |
| OGB4 INC |
Rho GTPase inhibitor for refrigerated platelet storage |
DE KOUCHKOVSKY, BRITTANY |
NHLBI |
CINCINNATI |
OH |
31-August-2025 |
| VIVONICS, INC. |
Near InfraRed Layered Imaging of Tissue Hemodynamics (NIR-LITH) |
PIERRO, MICHELE |
NIDDK |
Bedford |
MA |
31-August-2025 |
| WAVED MEDICAL LLC |
Image-based risk assessment to identify women at high-risk for breast cancer |
BATCHELDER, KENDRA |
NCI |
ORONO |
ME |
31-August-2025 |
| RISE THERAPEUTICS, LLC |
R-5280, A Novel Modified Superior Resistant Starch Therapy for Type 1 Diabetes |
FURLAN FREGUIA, CHRISTIAN |
NIDDK |
Rockville |
MD |
31-August-2025 |
| LUCIOLE PHARMACEUTICALS, INC. |
Discovery and development of OGG1 activators as precision drugs for modification of Alzheimer's disease progression. |
RUMSEY, WILLIAM L |
NIA |
Sherborn |
MA |
31-August-2025 |
| BLOOD CELL TECHNOLOGIES, LLC |
Development of a new class of BLVRB-targeted redox therapeutics in breast cancer |
MARCHENKO, NATALIA |
NCI |
Stony Brook |
NY |
31-August-2025 |
| VERY REAL HELP, LLC |
Cognitive Behavioral Immersion: A Randomized Control Trial of Peer-Based Coaching in the Metaverse |
ROBINSON, NOAH |
NIMH |
NASHVILLE |
TN |
31-August-2025 |
| UBITRIX INTERNATIONAL, INC. |
A Framework for mHealth App Security and Privacy Analysis |
AHAMED, SHEIKH IQBAL |
NLM |
MILWAUKEE |
WI |
31-August-2025 |
| RUSH RIVER RESEARCH CORPORATION |
Innovative Chair to Prevent Pressure Injuries in Persons Living with Alzheimer's Disease and Related Dementias |
LUNDSTROM, JULIE |
NIA |
ELLSWORTH |
WI |
31-August-2025 |
| AFASCI, INC. |
Clinical Phase I trials on an IND single molecule dual inhibitor of Cav3 channels and soluble epoxide hydrolase for treatment of neuropathic pain |
XIE, XINMIN SIMON |
NINDS |
REDWOOD CITY |
CA |
31-August-2025 |
| SILOAM VISION, INC. |
Validation of artificial intelligence (AI) based software as medical device (SaMD) for retinopathy of prematurity (ROP) |
JONAS, KARYN |
NEI |
LAKE OSWEGO |
OR |
31-August-2025 |
| VARIGEN BIOSCIENCES CORPORATION |
A Universal Fungal Transposase System for Increasing Natural Product and Protein Titers |
KNOX, BEN |
NCCIH |
Middleton |
WI |
31-August-2025 |
| ATTOGENE |
Convenient rapid and portable tool for the detection of ribonucleases |
FORD, LANCE P |
NIGMS |
AUSTIN |
TX |
31-August-2025 |
| COG ANALYTICS, LLC |
Mindfulness Based Stress Reduction App for African American Caregivers |
CARSWELL, STEVEN BERNARD |
NIA |
POTOMAC |
MD |
31-August-2025 |
| ONCOTRAP, INC. |
An Aptamer-directed IgG1-Fc Drug Conjugate (AFDC) for Treating Pancreatic Cancer |
GAO, XIANG |
NCI |
CHAPEL HILL |
NC |
31-August-2025 |
| KNOUBIS BIO, INC. |
Non-immunosuppressive rheumatoid arthritis DMARD |
STANFORD, STEPHANIE |
NIAMS |
San Diego |
CA |
31-August-2025 |
| GLYCOMIRA, LLC |
Development of a Diagnostic Test for Eosinophilic Chronic Rhinosinusitis |
PULSIPHER, ABIGAIL |
NIAID |
SALT LAKE CITY |
UT |
31-August-2025 |
| SCIOME, LLC |
Research and development of an adverse outcome pathway-focused mechanistic inference tool for 'omics data using semantic knowledge graphs |
SHAH, RUCHIR |
NIEHS |
RESEARCH TRIANGLE PARK |
NC |
31-August-2025 |
| ARMIDA LABS, INC. |
Targeting pancreatic cancer metastases with Targefrin |
BAGGIO, CARLO |
NCI |
SAN DIEGO |
CA |
31-August-2025 |
| SEQUITUR HEALTH CORP. |
Whole Blood Point of Care Metabolic Measurement |
THOMAS, MARYLAURA LIND |
NICHD |
SCOTTSDALE |
AZ |
31-August-2025 |
| ENDOMET BIOSCIENCES, INC |
Novel, Non-hormonal Therapeutic for Endometriosis |
PETROSSIAN, TANYA CHRISTINEH |
NICHD |
Irvine |
CA |
31-August-2025 |
| VIRTICI, LLC |
A Novel Antibody that Promotes Neuronal Integrity and Neurogenesis for Treating Alzheimer's Disease |
FANGER, NEIL A |
NIA |
Seattle |
WA |
31-August-2025 |
| RAFT PHARMACEUTICALS, LLC |
Novel biologic to treat chemotherapy-induced neuropathic pain |
KOGAN, YAKOV |
NCI |
SAN DIEGO |
CA |
31-August-2025 |
| OPTOSURGICAL, LLC |
hANDY-i(TM): A non-invasive, dual-sensor handheld imager for intraoperative preservation of parathyroid glands |
OH, EUGENE |
NIBIB |
WILMINGTON |
DE |
31-August-2025 |
| PERICOR, LLC |
PeriPath: A Single Incision Delivery Tool for Epicardial Pacing and Defibrillation: Phase 2 |
OPFERMANN, JUSTIN |
NHLBI |
BETHESDA |
MD |
31-August-2025 |
| AVANTI BIOSCIENCES, INC. |
Development of DYRK1A allosteric modulator for the treatment of Alzheimer's Disease |
ARALDI, GIAN LUCA |
NIA |
EAST SETAUKET |
NY |
31-August-2025 |
| KUDA THERAPEUTICS, INC. |
Development of a novel dual HIF-α inhibitor and inducer of ferroptosis for kidney cancer |
LIPPERT, ROBERT |
NCI |
Salt Lake City |
UT |
31-August-2025 |
| MASSACHUSETTS NEURO TECHNOLOGY, INC. |
Developing a virtual reality guided acupuncture imagery treatment for Chronic low back pain |
KONG, JIAN |
NCCIH |
WESTON |
MA |
31-August-2025 |
| SILVERBILLS INC. |
SilverBills: A Legal, Technical and Financial Tool for Aging LGBTQ+ Individuals with Impaired Cognition. |
LOBEL-ESRIG, MARCI |
NIA |
NEW ROCHELLE |
NY |
31-August-2025 |
| STRYKAGEN CORPORATION |
Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy |
WUEBBLES, RYAN DAVID |
OD |
RENO |
NV |
31-August-2025 |
| EYSZ, INC. |
A Mobile Health Application to Detect Absence Seizures using Hyperventilation and Eye-Movement Recordings |
KUPERMAN, RACHEL |
NINDS |
Berkeley |
CA |
31-August-2025 |
| EXHALIX, LLC |
HEALS™: An Active Hydrogen Sulfide Delivery Technique for Accelerated, Effective Wound Healing |
SHEKARRIZ, REZA |
NIGMS |
Albuquerque |
NM |
31-August-2025 |
| PHYSICAL SCIENCES, INC |
Evaluation of photoreceptors health and function in diabetic retinopathy patients using a high-resolution retinal imaging device with controlled light stimulus |
MUJAT, MIRCEA |
NEI |
ANDOVER |
MA |
31-August-2025 |
| PREVEP, INC. |
Treatment of status epilepticus and refractory status epilepticus with intravenous topiramate. |
KLEIN, PAVEL |
NINDS |
BETHESDA |
MD |
31-August-2025 |
| BRIDGESOURCE MEDICAL CORPORATION |
Medical Device Identifier to Improve Emergency Triage |
WALMSLEY, JOHN |
NIA |
AUSTIN |
TX |
31-August-2025 |
| KOLI, INC. |
Koli: A non-surgical solution for gallstone disease |
CHENG, CHRISTOPHER |
NIDDK |
PALO ALTO |
CA |
31-August-2025 |
| EVOQ THERAPEUTICS, INC. |
New approach for immune modulation against T1D |
DANIEL, WESTON |
NIDDK |
ANN ARBOR |
MI |
31-August-2025 |
| MICROSENSOR LABS, LLC |
SBIR Fast Track: Development of a High-throughput Magnetic Cytometer for Single Cell Sorting |
LIU, PENG |
NIGMS |
CHICAGO |
IL |
31-August-2025 |
| AFASCI, INC. |
Development of a Novel Medication for Alcohol Use Disorder with an Active IND Dual Inhibitor of T-Type Calcium Channel and Soluble Epoxide Hydrolase |
XIE, XINMIN SIMON |
NIAAA |
REDWOOD CITY |
CA |
31-August-2025 |
| CAPTIS DIAGNOSTICS |
A nanosized magnetic particle system for fast and efficient neuronal extracellular vesicle enrichment from plasma |
MILOSEVIC, JADRANKA |
NIA |
Pittsburgh |
PA |
31-August-2025 |
| BIOMARKER CORPORATION |
Genomic marker to distinguish aggressive and indolent prostate cancer |
DAVIS, RANDALL |
NCI |
SOUTH SAN FRANCISCO |
CA |
31-August-2025 |
| OAK RIDGE THERAPEUTIC DISCOVERY (ORRXD), LLC |
Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis. |
QUARLES, L DARRYL |
NIA |
MEMPHIS |
TN |
31-August-2025 |
| MOGLING BIO INC |
Pharmacological rejuvenation of human hematopoietic stem cells |
MULLOY, JAMES C |
NHLBI |
CINCINNATI |
OH |
31-August-2025 |
| ADVANCED MEDICAL ELECTRONICS CORPORATION |
Ring wearable sensor use for diagnosis and monitoring of Parkinson's disease in underserved rural populations |
HAVEY, GARY D |
NIMHD |
MAPLE GROVE |
MN |
31-August-2025 |
| GSNO THERAPEUTICS, INC. |
Modulation of Protein S-nitrosylation Signaling as a Potential Therapeutic Breakthrough in Rheumatoid Arthritis |
BRADLEY, MATTHEWS OGDEN |
NIAMS |
SHELTON |
WA |
31-August-2025 |
| SONOVANCE, INC. |
Low-Cost Ultrasound Imaging for In-Home, Rural, and Clinic Care Without The Need For Trained Staff |
RAGHAVAN, RAGHU |
NIBIB |
BALTIMORE |
MD |
31-August-2025 |
| SCIENTIFIC HORIZONS CONSULTING LLC |
A Novel Aerosolization and Inhalation Platform for the Pulmonary Delivery of Anti-inflammatory Agents to Distal Airways for the Enhanced Pain Management in Chronic Obstructive Pulmonary Disease (COPD) |
GAO, XIANG |
NHLBI |
Irvine |
CA |
31-August-2025 |
| SOUTH RAMPART PHARMA, LLC |
Novel non-narcotic analgesic for acute and chronic pain |
NAISMITH, ROBERT |
NINDS |
NEW ORLEANS |
LA |
31-August-2025 |
| NEUROGENECES, INC. |
A Machine Learning Algorithm to Assess Functional "Brain Age" from an In-Home EEG Sleepband |
COMERFORD, MICHAEL |
NIA |
SANTA FE |
NM |
31-August-2025 |
| TRANSCHROMIX, LLC. |
Novel brain-penetrant drugs for translation-targeting therapeutics of Alzheimer’s disease |
CHEN, XIAN |
NIA |
CHAPEL HILL |
NC |
31-August-2025 |
| ENDOMIMETICS, LLC |
Bionanomatrix coating to enhance antibacterial effects while reducing inflammation of knee joint implants |
SHERWOOD, JENNIFER |
NIAMS |
BIRMINGHAM |
AL |
31-August-2025 |
| LINK BIOSYSTEMS INC. |
EFFICIENT SCALE-UP OF IPS CELLS FOR AUTOLOGOUS CELL THERAPY WORKFLOW |
RONALDSON, KACEY |
NCI |
IRVINGTON |
NY |
31-August-2025 |
| LIPO-IMMUNO TECH, LLC |
Programming Metabolically Fit TILs for Immunotherapy |
MEHROTRA, SHIKHAR |
NCI |
MOUNT PLEASANT |
SC |
31-August-2025 |
| NEPHROGEN INC. |
CRISPR-Cas Editing as a Genetic Cure for Autosomal Dominant Polycystic Kidney Disease |
MAXIM, DEMETRIOS S |
NIDDK |
NEW YORK |
NY |
31-August-2025 |
| PHARMAIN CORPORATION |
Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and human |
ALFARO, JOSHUA |
NCI |
BOTHELL |
WA |
31-August-2025 |
| NAVEGA THERAPEUTICS, INC. |
Advancing precision pain medicines to the clinic |
MORENO, ANA MARIA |
NINDS |
SAN DIEGO |
CA |
31-August-2025 |
